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Physical, chemical and biological studies of gelatin/chitosan based transdermal films with embedded silver nanoparticles
Conclusions Based on these observations, in vitro performances against various characteristics of transdermal film, would be utilized as a distinct dressing material and patches accessible in market. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

Evaluation of phytochemical constituents by GC-MS and antidepressant activity of Peganum harmala L. seeds extract
Conclusions This indicates that the seeds extract can correct the depression and reach the normal state of the treated animals. The results demonstrated that seeds represented a source of indole alkaloids (harmaline, harmine and tetrahydroharmine). (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

In vitro study on the inhibitory effect of ketamine to LPS-induced apoptosis in HUVEC culture
Conclusions At least in part, ketamine was suggested to have inhibitory effect in apoptosis mechanism. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

A hospital-based study of hepatic dysfunction in children with dengue fever
Conclusions Tender hepatomegaly and elevated liver enzymes were seen more frequently in severe dengue. There was significant derangement between liver function and tender hepatomegaly. Altered liver function may be evident even in the absence of hepatomegaly. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

Alternations in parasitological, biochemical and molecular parameters of Biomphalaria alexandrina snails, intermediate host of Schistosoma mansoni, induced post exposure to the proposed snail biocontrol agent Phasmarhabditis hermaphrodita nematode
Conclusions It is concluded that exposure of B. alexandrina snails to P. hermaphrodita nematode deteriorates their biological, parasitological, biochemical and molecular parameters, rendering them to be unsuitable for schistosomiasis transmission. However, comprehensive tests are needed to determine efficacy of P. hermaphrodita as a schistosomiasis biocontrol agent aiming to incorporate in control program of this parasite. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

In vitro antiplasmodial efficacy of mangrove plant, Ipomoea pes-caprae against Plasmodium falciparum (3D7 strain)
Conclusions This is the first report of antimalarial activity of I. pes-caprae and it is concluded that the methanolic extract of root is potent for the development of new antimalarial drugs. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

Comparative biochemical and pathological changes in some laboratory animals experimentally infected with Trypanosoma brucei and their responses to diminazene diaceturate (Veriben®) therapy
Conclusions Diminazene diaceturate was able to ameliorate the various biochemical and pathological changes which were suggestive of severe liver and kidney dysfunctions with greater intensity occurring among mice and rats as compared to rabbits. Therefore, it suggested that mice and rats could be better animal models for studying the disease than rabbits. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

Studies on antigenic cross-reactivity of Trichuris ovis with host mucosal antigens in goat
Conclusions The antigenic cross-reactivity was thought to result from shared antigens. The existence of paracloacal papillae found in the anterior part of the male was not a unique feature for species differentiation. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

Laboratory rearing of Cimex hemipterus F. (Hemiptera: Cimicidae) feeding on different types of human blood compositions by using modified artificial feeding system
Conclusions The components in the blood sources may be the key to their different effects on the growth dynamics of C. hemipterus. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

A systematic review of the effects of Iranian pharmaceutical plant extracts on Giardia lamblia
This study aimed to provide a systematic review regarding anti-Giardia effect of different Iranian plant extracts used in vivo and in vitro on cysts and trophozoites. Many reports indicated that most of plant extracts used as anti-Giardia were obtained from Liliaceae, Apiaceae, Asteraceae, and Myrtaceae. These extracts included different fractions such as aqueous, alcoholic and chloroform extracts as well as Soxhlet extraction of juice or essence. The findings of this review showed that hydroalcoholic extract of asafoetida, Chenopodium botrys, and chloroformic extract of feverfew (Tanacetum parthenium) have the maximum eff...
Source: Asian Pacific Journal of Tropical Disease - December 19, 2015 Category: Tropical Medicine Source Type: research

Significance of correct identification of larval trematodes in molluscs
Publication date: November 2015 Source:Asian Pacific Journal of Tropical Disease, Volume 5, Issue 11 Author(s): Hudson Alves Pinto, Alan Lane de Melo (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 10, 2015 Category: Tropical Medicine Source Type: research

Evaluation of in vitro antioxidant and anti-inflammatory activities of Ximenia americana extracts
Conclusions The present study revealed that different solvent extracts of Ximenia americana leaves contain broad spectrum of bioactive compounds. Results confirm that aqueous extract exhibited high antioxidant activity and methanol extract exhibited high anti-inflammatory activity. Further study requires purification, characterization and structural elucidation of phenolic compounds in both extracts that may help in the development of new phytopharmaceuticals. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 10, 2015 Category: Tropical Medicine Source Type: research

In vitro evaluation of antioxidant and antidiabetic activities of Syzygium densiflorum fruits
Conclusions In vitro evaluations confirmed the antioxidant and antidiabetic potential of S. densiflorum fruits. Ethanol extract of S. densiflorum fruits showed higher activity with statistical significance vs. ethyl acetate and n-hexane extracts. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 10, 2015 Category: Tropical Medicine Source Type: research

Correlation between climate variations and rotavirus diarrhea in under-five children in Bandung
Conclusions Our study showed that rotavirus is found year-round, and has a negative correlation to temperature, a moderate correlation only to humidity, but no significant correlation at all to either rainfall or wind speed. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 10, 2015 Category: Tropical Medicine Source Type: research

Comparative study of in vitro antibacterial activity of leaves, bark, heart wood and seed extracts of Caesalpinia sappan L.
Conclusions The heart wood extracts showed the highest antibacterial activity having a minimal inhibition concentration of 2 mg/mL in all three solvents against the four bacterial strains, except petroleum ether where MIC was 5 mg/mL against E. coli and B. subtilis. The aqueous and methanolic extracts of bark showed minimal inhibition concentrations of 5 mg/mL and 2 mg/mL against K. pneumoniae respectively whereas aqueous extract of bark showed a minimal inhibition concentration of 5 mg/mL against E. coli. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - December 10, 2015 Category: Tropical Medicine Source Type: research