Comparative biochemical and pathological changes in some laboratory animals experimentally infected with Trypanosoma brucei and their responses to diminazene diaceturate (Veriben®) therapy

Conclusions Diminazene diaceturate was able to ameliorate the various biochemical and pathological changes which were suggestive of severe liver and kidney dysfunctions with greater intensity occurring among mice and rats as compared to rabbits. Therefore, it suggested that mice and rats could be better animal models for studying the disease than rabbits.
Source: Asian Pacific Journal of Tropical Disease - Category: Tropical Medicine Source Type: research