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Ebola virus disease: How can African pharmacists respond to future outbreaks?
Publication date: May 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 5 Author(s): Peter Bai James, Shazia Qasim Jamshed, Isha Patel In its forty years history (1976–2016), the West African region has recorded the most devastating form of the Ebola virus disease. The sparse knowledge of healthcare professionals and general public combined with lesser responses from international community are major factors for the dissemination of the disease. In the context of this outbreak, there is a need to highlight the roles and responsibilities of pharmacists, especially in the African healthcare s...
Source: Asian Pacific Journal of Tropical Disease - May 25, 2016 Category: Tropical Medicine Source Type: research

Green tea phytocompounds as anticancer: A review
Publication date: April 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 4 Author(s): Najeeb Ullah, Mahboob Ahmad, Hasnain Aslam, Muhammad Asad Tahir, Muhammad Aftab, Noreen Bibi, Sohail Ahmad Green tea is universally considered significant and its benefits have been experimentally explored by researchers and scientists. Anticancer potential of green tea has been completely recognized now. Green tea contains anti-cancerous constituents and nutrients that have powerful remedial effects. By using electronic data base (1998–2015), different compounds in green tea possessing anticancer...
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Acute fulminant myocarditis in a case of dengue fever: A case report
We reported a 5-year-old boy who presented with fulminant viral myocarditis due to dengue infection and died within 24 h. Biopsy of heart revealed lymphocytic infiltration. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Genotoxic effect of the tricyclic antidepressant drug clomipramine hydrochloride in somatic and germ cells of male mice
Conclusions It is concluded that CH has genotoxic effect in somatic and germ cells of mice as well as damaging effect on liver tissue after treatment with the medium and the high doses. However, the usage of low dose (especially for short time, 5 days) can be utilized as a safe therapeutic dose. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Pharmacognostic standardization and HPTLC analysis of the leaves of Hiptage benghalensis (L.) Kurz
Conclusions Results of the present study can serve as a marker for authentic identification and authentication of the plant of this taxon. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Novel synthesis of silver nanoparticles using melon aqueous extract and evaluation of their feeding deterrent activity against housefly Musca domestica
Conclusions Fresh melon extract resulted in a simple one-step formation of AgNPs with better control over the size of the material and the noteworthy insecticidal activity was displayed. This study proved the insecticidal potential of AgNPs against Musca domestica and its candidacy for replacing commercially available insecticides (organic/inorganic) which are synthesized in nature. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Phytochemical, organoleptic and ferric reducing properties of essential oil and ethanolic extract from Pistacia lentiscus (L.)
Conclusions The present study reveals the presence of various phytochemical classes in P. lentiscus, and the antioxidant experiment shows a good bioactivity of the aerial parts of the Algerian P. lentiscus. The literature review of the essential oil composition shows also important variations due to geographic and environmental conditions. This preliminary investigation will help explore the bioactive compounds of P. lentiscus, and will bring data for a better physicochemical and organoleptic classification of the Algerian variety. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

In vivo antidiabetic and antioxidant activities of Coccinia grandis leaf extract against streptozotocin induced diabetes in experimental rats
Conclusions The results suggest that Coccinia grandis ethanolic leaf extract has strong antidiabetic activity and can be meaningfully utilized in the management of diabetes. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Effects of Calophyllum inophyllum fruit extract on the proliferation and morphological characteristics of human breast cancer cells MCF-7
Conclusions This study clearly proved that the proliferation of human breast cancer cell MCF-7 was inhibited by C. inophyllum fruit extract resulted from the induction of apoptosis in MCF-7 cells. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Toxic effect of chemicals dumped in premises of UCIL, Bhopal leading to environmental pollution: An in silico approach
Conclusions In summary, findings suggested that toxic exposure of carbaryl and alpha-naphthol as compared to butylated hydroxytoluene generated immunotoxicity and disrupted the functioning of immune system thus it may have caused an increase in susceptibility to Mycobacterium tuberculosis infection. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Investigation on prevalence of Escherichia coli strains carrying virulence genes ipaH, estA, eaeA and bfpA isolated from different water sources
Conclusions Our finding showed that the prevalence rates of virulence genes ipaH and estA were very high among E. coli strains isolated from different surface water sources in Alborz Province. Considering their plasmid-borne nature, the risk of transmission of these genes between other bacterial species could pose a high threat to public health. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Life table analysis of Cimex hemipterus F. (Hemiptera: Cimicidae) reared on different types of human blood
Conclusions Different blood sources may have different effects on the development time and life characteristics of bed bugs. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Longer lead time of tuberculosis laboratory commodities in Amhara region, Ethiopia
Conclusions One fourth of health centers had longer lead time of TB laboratory commodities as a result of transportation delay. Thus, decentralization of transportation with dedicated vehicles is recommended to shorten lead times. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

The levels of Toxoplasma gondii profilin and adiponectin in obese patients complicated with or without metabolic syndrome as compared to non-obese patients
Conclusions The level of T. gondii profilin in obese patients was higher than that in the non-obese, whereas the level of adiponectin in obese patients complicated with metabolic syndrome was lower than that in the obese without metabolic syndrome and non-obese patients. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research

Do we need to screen Egyptian voluntary blood donors for toxoplasmosis?
Conclusions It might be appropriate to include the screening of blood and blood products for T. gondii in the pre-transfusion blood testing schedule in Egypt. Also, molecular screening should be carried out on the blood being transfused to immunocompromised patients. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - April 29, 2016 Category: Tropical Medicine Source Type: research