Continued persistence of ECSA genotype with replacement of K211E in E1 gene of Chikungunya virus in Delhi from 2010 to 2014
Publication date: July 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 7 Author(s): Priyanka Singh, Pankaj Sharma, Sachin Kumar, Mala Chhabra, Moshahid Alam Rizvi, Veena Mittal, Dipesh Bhattacharya, Srinivas Venkatesh, Arvind Rai Chikungunya is a viral disease caused by arthropod-borne Chikungunya virus (CHIKV) and transmitted by Aedes mosquitoes. In 2006, CHIKV re-emerged in Indian Ocean islands, Southeast Asia and India. Delhi witnessed the continued occurrence of CHIKV after its first outbreak in 2010. The constant monitoring of the circulating strains of CHIKV is important f...
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Phytochemical screening, antioxidant and antimicrobial potential of stem barks of Coula edulis Baill. Pseudospondias longifolia Engl. and Carapa klaineana Pierre. from Gabon
Conclusions Our results suggest that C. edulis extracts contain greater antioxidant and antimicrobial properties than P. longifolia and C. klaineana extracts. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Biological application of green silver nanoparticle synthesized from leaf extract of Rauvolfia serpentina Benth
Conclusions Synthesized spherical shaped AgNPs from the leaf extract of Rauvolfia serpentina Benth have antimicrobial and larvicidal activities as well as cytotoxicity against HeLa and MCF-7 cell lines. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Induction of apoptosis in HepG2 by Vitex agnus-castus L. leaves extracts and identification of their active chemical constituents by LC-ESI-MS
Conclusions The butanolic fraction has higher contents of secondary metabolites than the defatted methanolic extract. The cytotoxic activities, apoptotic changes, and caspase-3 activation may be due to the presence of these bioactive secondary metabolites (iridoids, flavonoid, and phenolic acids) in these extracts. These results would suggest V. agnus-castus to be used as an adjuvant in cancer therapy. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Slow release formulations of Bacillus thuringiensis israelensis (AM 65-52) and spinosyns: effectiveness against the West Nile vector Culex pipiens in Saudi Arabia
Conclusions Our results highlighted the effectiveness of B. thuringiensis israelensis and spinosyns against an important West Nile vector, providing baseline data to develop eco-friendly mosquito control programs in Saudi Arabia. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Comparative parasitaemia and haematology of mice, rats and rabbits experimentally infected with Trypanosoma brucei brucei and their responses to diminazene diaceturate (VeribenĀ®) therapy
Conclusions Mice and rats are better animal models for studying the progression of the disease than rabbits and diminazene diaceturate (VeribenĀ®) is capable of eliminating parasitaemia and modulating haematological changes in mice, rats and rabbits. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Lymphatic filariasis: Surveillance action among immigrants from endemic areas, Acre State, Brazilian Amazon
Conclusions This surveillance action reveals, in a pioneering and unequivocal manner, that Brazil is an influx of immigrants carrying lymphatic filariasis and there is an urgent need to step up surveillance at the main entry point for immigrants. Active surveillance may prevent the reintroduction of lymphatic filariasis in areas under control, or prevent its introduction into other states of Brazil. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Genetic diversity of rotavirus strains in children with diarrhea in Lagos, Nigeria
Conclusions The study highlights the wide diversity of rotavirus strains and the potential emergence of unusual rotavirus in this region. It is therefore important to continue the epidemiological studies to monitor rotavirus strains associated with gastroenteritis in hospitals before and after the introduction of rotavirus vaccine. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Evaluation of HBV resistance to tenofovir in patients with chronic hepatitis B using ZNA probe assay in Kerman, southeast of Iran
Conclusions HBeAg had a correlation with A194T mutation (P = 0.02) and tenofovir resistance was seen in 13 patients. Real-time PCR with zip nucleic acid probes is a rapid method to detect mutations in the polymerase region of HBV with high sensitivity and specifity. This method could be used for mutation detection in nt-194 position of polymerase gene for tenofovir resistance and other mutations in drug resistance researches. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Serological markers of Epstein-Barr virus in renal transplant recipients
Conclusions Finally we concluded that most Sudanese renal transplants recipient studied were previously infected with Epstein-Barr virus, while few of them were recently infected. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

Visceral leishmaniasis: an update of laboratory diagnosis
Publication date: July 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 7 Author(s): Zineb Tlamcani Visceral leishmaniasis, is an infection due to obligate intracellular protozoa of the genus Leishmania. There exist two varieties of visceral leishmaniasis, that vary in their transmission aspects: zoonotic visceral leishmaniasis and anthroponotic visceral leishmaniasis. Their clinical features are comparable with sevral differences. Laboratory diagnosis of visceral leishmaniasis consists of microscopic observation of parasite, culture from appropriate samples, detection of antigen, serological te...
Source: Asian Pacific Journal of Tropical Disease - July 9, 2016 Category: Tropical Medicine Source Type: research

A probe into biochemical potential of Aconitum violaceum: A medicinal plant from Himalaya
Publication date: June 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 6 Author(s): Sidra Sabir, Muhammad Arshad, Mubashir Hussain, Huma Mehreen Sadaf, Sohail, Muhammad Imran, Farhat Yasmeen, Saboon, Sunbal Khalil Chaudhari Aconitum violaceum Jacq. ex Stapf belonging to family Ranunculaceae is an important medicinal plant of Himalaya regions. Its medicinal potential is due to the presence of pharmacologically active compounds such as At, aconitine, benzoic acid, aconine and flavanoids. This plant has notable antioxidant, anti-inflammatory and analgesic properties. Traditional...
Source: Asian Pacific Journal of Tropical Disease - June 29, 2016 Category: Tropical Medicine Source Type: research

Phytochemistry, biological activities and economical uses of the genus Sterculia and the related genera: A reveiw
Publication date: June 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 6 Author(s): Moshera Mohamed El-Sherei, Alia Yassin Ragheb, Mona El Said Kassem, Mona Mohamed Marzouk, Salwa Ali Mosharrafa, Nabiel Abdel Megied Saleh The genus Sterculia is represented by 200 species which are widespread mainly in tropical and subtropical regions. Some of the Sterculia species are classified under different genera based on special morphological features. These are Pterygota Schott & Endl., Firmiana Marsili, Brachychiton Schott & Endl., Hildegardia Schott & Endl., Pterocymbi...
Source: Asian Pacific Journal of Tropical Disease - June 29, 2016 Category: Tropical Medicine Source Type: research

Cryptococcosis infection among HIV patients
Publication date: June 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 6 Author(s): Zineb Tlamcani Cryptococcosis is commonly known as a central nervous system infection due to Cryptococcus neoformans. It is one of the most frequent infections in AIDS patients. Disseminated cryptococcosis appears in almost one third of these patients. In this review, we will discuss the clinical presentation of cryptococcal infections among HIV patients and various methods of diagnosis, such as India ink, latex agglutination test and culture. (Source: Asian Pacific Journal of Tropical Disease)
Source: Asian Pacific Journal of Tropical Disease - June 29, 2016 Category: Tropical Medicine Source Type: research

Nephritic syndrome and anasarca in a case of lymphatic filariasis: A rare association
Publication date: June 2016 Source:Asian Pacific Journal of Tropical Disease, Volume 6, Issue 6 Author(s): Ayan Basu, Menal Wali, Bisakh Bhattacharya, Mehebubar Rahman, Yogiraj Ray, Rama Prosad Goswami Lymphatic filariasis is caused by a nematode, namely, Wuchereria bancrofti, Brugia malayi and Brugia timori. Lymphatic filariasis is a spectrum of illness and can manifest as, asymptomatic microfilaria, acute lymphatic filariasis, chronic lymphatic filariasis, tropical pulmonary eosinophilia and some systemic manifestations which involves joint, heart, kidney, nerve etc. Here, we present a case of anasarca wi...
Source: Asian Pacific Journal of Tropical Disease - June 29, 2016 Category: Tropical Medicine Source Type: research