Genotoxic effect of the tricyclic antidepressant drug clomipramine hydrochloride in somatic and germ cells of male mice

Conclusions It is concluded that CH has genotoxic effect in somatic and germ cells of mice as well as damaging effect on liver tissue after treatment with the medium and the high doses. However, the usage of low dose (especially for short time, 5 days) can be utilized as a safe therapeutic dose.
Source: Asian Pacific Journal of Tropical Disease - Category: Tropical Medicine Source Type: research