Cell Death, Nucleic acids and Immunity: Inflammation beyond the Grave
This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 13, 2018 Category: Rheumatology Authors: Keith B. Elkon Tags: Review Article Source Type: research
Neurobiological features of fibromyalgia are also present among rheumatoid arthritis patients
ConclusionsRA patients who have increased levels of FMness appear to share neurobiological features consistently observed in FM patients. This study is the first to provide neuroimaging evidence that RA is a mixed pain state, with many patients’ symptoms being related to CNS rather than classic inflammatory mechanisms.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 13, 2018 Category: Rheumatology Authors: Neil Basu, Chelsea M Kaplan, Eric Ichesco, Tony Larkin, Richard E Harris, Alison Murray, Gordon Waiter, Daniel J Clauw Tags: Full Length Source Type: research
Augmented Th17 Differentiation Leads to Cutaneous and Synovio ‐Entheseal Inflammation in a Novel Model of Psoriatic Arthritis
ConclusionPerturbation of the IL‐23/Th17 axis instigates Th17‐mediated inflammation in R26STAT3Cstopfl/fl CD4Cre mice, leading to cutaneous and synovio‐entheseal inflammation, and bone pathology highly reminiscent of psoriatic arthritis. Both IL‐17A and IL‐22 produced by Th17 cells play critical roles in promoting the cutaneous and musculoskeletal inflammation that characterizes psoriatic arthritis..This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 13, 2018 Category: Rheumatology Authors: Lu Yang, Melania H. Fanok, Aranzazu Mediero ‐Munoz, Laura K Fogli, Carmen Corciulo, Shahla Abdollahi, Bruce N. Cronstein, Jose U. Scher, Sergei B. Koralov Tags: Full Length Source Type: research
Necessity for interrupted time series to analyze the effects of propoxyphene withdrawal from the market and health outcome trend estimates
This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 13, 2018 Category: Rheumatology Authors: Ahl Jeffrey Caseja, Johnson Ukken, Mary Froehlich, Hamayon Babary, Yong ‐Jae Lee, Ji Won Yoo Tags: Letter to the Editor Source Type: research
“STATus of STAT3 in Psoriatic Arthritis.”
This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 13, 2018 Category: Rheumatology Authors: John D. Mountz Tags: Editorial Source Type: research
Frequency and anatomical distribution of magnetic resonance imaging features in sacroiliac joints of young athletes: Exploring “background noise” towards a data‐driven definition of sacroiliitis in early spondyloarthritis
ConclusionIn recreational and elite athletes, BME showed on average in 3‐4 SIJ quadrants, meeting the ASAS definition in 30%‐41%. The posterior lower ilium was the single most affected SIJ region. These findings in athletes help refine data‐driven thresholds for defining sacroiliitis in early SpA.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 12, 2018 Category: Rheumatology Authors: Ulrich Weber, Anne Grethe Jurik, Anna Zejden, Ejnar Larsen, Steen Hylgaard J ørgensen, Kaspar Rufibach, Christian Schioldan, Søren Schmidt‐Olsen Tags: Full Length Source Type: research
Differential points of widening and pseudo ‐widening of sacroiliac joint: Feature of image
This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 9, 2018 Category: Rheumatology Authors: Seung ‐Jin Yoo, Seunghun Lee, Jeong Ah Ryu Tags: Clinical Image Source Type: research
Screening High Resolution Computed Tomography of the Chest to Detect Interstitial Lung Disease in Systemic Sclerosis: A Global Survey of Rheumatologists
This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 9, 2018 Category: Rheumatology Authors: Elana J. Bernstein, Dinesh Khanna, David J. Lederer Tags: Concise Communication Source Type: research
The genetic profile of RF ‐positive polyarticular juvenile idiopathic arthritis (JIA) resembles adult rheumatoid arthritis (RA)
ConclusionsRF‐positive polyarticular JIA is genetically more similar to adult RA than to the most common JIA categories and thus appears to be a childhood‐onset presentation of autoantibody positive RA. These findings suggest common disease mechanisms, which could lead to novel therapeutic targets and shared treatment strategies.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 9, 2018 Category: Rheumatology Authors: Anne Hinks, Miranda C Marion, Joanna Cobb, Mary E Comeau, Marc Sudman, Hannah C Ainsworth, John Bowes, , Mara L Becker, John F Bohnsack, Johannes ‐Peter Haas, Daniel J Lovell, Elizabeth D Mellins, J Lee Nelson, Ellen Nordal, Marilynn Punaro, Ann M Reed, Tags: Brief Report Source Type: research
Editorial: The American College of Rheumatology White Paper on Biosimilars: It Isn't All White —There Is Some Gray and Black
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 7, 2018 Category: Rheumatology Authors: Roy Fleischmann Tags: Editorial Source Type: research
The Science Behind Biosimilars
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 7, 2018 Category: Rheumatology Authors: S. Louis Bridges, Douglas W. White, Angus B. Worthing, Ellen M. Gravallese, James R. O'Dell, Kamala Nola, Jonathan Kay, Stanley B. Cohen, Tags: Special Article Source Type: research
The American College of Rheumatology White Paper on Biosimilars: It Isn't All White —There Is Some Gray and Black
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 7, 2018 Category: Rheumatology Authors: Roy Fleischmann Tags: Editorial Source Type: research
The American College of Rheumatology White Paper on Biosimilars – It isn't all White ‐ there is some gray and black
This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 7, 2018 Category: Rheumatology Authors: Roy Fleischmann Tags: Editorial Source Type: research
Brief Report: Validation of a Definition of Flare in Patients With Established Gout
ConclusionThe definition of gout flare that requires fulfillment of at least 3 of 4 patient‐reported criteria is now validated to be sensitive, specific, and accurate for gout flares, as demonstrated using an independent large international patient sample. The availability of a validated gout flare definition will improve the ascertainment of an important clinical outcome in studies of gout. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 6, 2018 Category: Rheumatology Authors: Angelo L. Gaffo, Nicola Dalbeth, Kenneth G. Saag, Jasvinder A. Singh, Elizabeth J. Rahn, Amy S. Mudano, Yi ‐Hsing Chen, Ching‐Tsai Lin, Sandra Bourke, Worawit Louthrenoo, Janitzia Vazquez‐Mellado, Hansel Hernández‐Llinas, Tuhina Neogi, Ana Beatri Tags: Brief Report Source Type: research
Brief Report: Cancer Immunotherapy in Patients With Preexisting Rheumatic Disease: The Mayo Clinic Experience
ConclusionTo our knowledge, this represents the largest single‐center cohort of patients with rheumatic diseases who were exposed to modern cancer immunotherapy. Only a minority of these patients experienced a flare of their preexisting rheumatic disease or any other IRAE. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - February 6, 2018 Category: Rheumatology Authors: Michael D. Richter, Olga Pinkston, Lisa A. Kottschade, Heidi D. Finnes, Svetomir N. Markovic, Uma Thanarajasingam Tags: Brief Report Source Type: research
