The genetic profile of RF ‐positive polyarticular juvenile idiopathic arthritis (JIA) resembles adult rheumatoid arthritis (RA)

ConclusionsRF‐positive polyarticular JIA is genetically more similar to adult RA than to the most common JIA categories and thus appears to be a childhood‐onset presentation of autoantibody positive RA. These findings suggest common disease mechanisms, which could lead to novel therapeutic targets and shared treatment strategies.This article is protected by copyright. All rights reserved.

Source: Arthritis and Rheumatism - February 9, 2018 Category: Rheumatology Authors: Anne Hinks, Miranda C Marion, Joanna Cobb, Mary E Comeau, Marc Sudman, Hannah C Ainsworth, John Bowes, , Mara L Becker, John F Bohnsack, Johannes ‐Peter Haas, Daniel J Lovell, Elizabeth D Mellins, J Lee Nelson, Ellen Nordal, Marilynn Punaro, Ann M Reed, Tags: Brief Report Source Type: research