Chikungunya Virus Arthritis: Implications of Acute and Chronic Inflammation Mechanisms on Patient Management
This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 29, 2017 Category: Rheumatology Authors: Ali Zaid, Patrick G érardin, Adam Taylor, Helen Mostafavi, Denis Malvy, Suresh Mahalingam Tags: Review Article Source Type: research
Hypomethylation of CYP2E1 and DUSP22 promoters associated with disease activity and erosive disease among rheumatoid arthritis patients
ConclusionMethylation signatures specific to RA clinical outcomes may have utility as biomarkers or predictors of exposure, disease progression and severity.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 29, 2017 Category: Rheumatology Authors: Amanda Mok, Brooke Rhead, Calliope Holingue, Xiaorong Shao, Hong L. Quach, Diana Quach, Elizabeth Sinclair, Jonathan Graf, John Imboden, Thomas Link, Ruby Harrison, Vladimir Chernitskiy, Lisa F. Barcellos, Lindsey A. Criswell Tags: Full Length Source Type: research
ACR Announcements
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 27, 2017 Category: Rheumatology Tags: ACR Announcements Source Type: research
Clinical Connections
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 27, 2017 Category: Rheumatology Tags: Clinical Connections Source Type: research
In This Issue
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 27, 2017 Category: Rheumatology Tags: In This Issue Source Type: research
Issue Information
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 27, 2017 Category: Rheumatology Tags: Issue Information Source Type: research
Brief Report: Loss of Muscle Strength Prior to Knee Replacement: A Question of Anatomic Cross ‐Sectional Area or Specific Strength?
ConclusionPrior to knee replacement, a significant reduction in knee extensor strength appears to occur in women through 2 mechanisms: one driven by pain (loss of specific strength) and one independent of pain (loss of muscle anatomic cross‐sectional area). Men who underwent knee replacement showed significantly reduced levels of extensor anatomic cross‐sectional area, but not significantly lower strength or specific strength. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 20, 2017 Category: Rheumatology Authors: Adam G. Culvenor, Felix C. Hamler, Jana Kemnitz, Wolfgang Wirth, Felix Eckstein Tags: Brief Report Source Type: research
Brief Report: A Phase IIb Trial of a Novel Extended ‐Release Microsphere Formulation of Triamcinolone Acetonide for Intraarticular Injection in Knee Osteoarthritis
ConclusionAlthough the primary end point was not met, our findings indicate a prolonged reduction in symptoms with FX006 with an evident dose response and a safety profile similar to saline placebo. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 20, 2017 Category: Rheumatology Authors: Philip G. Conaghan, Stanley B. Cohen, Francis Berenbaum, Joelle Lufkin, James R. Johnson, Neil Bodick Tags: Brief Report Source Type: research
Loss of Muscle Strength Prior to Knee Replacement: A Question of Anatomic Cross ‐Sectional Area or Specific Strength?
ConclusionPrior to knee replacement, a significant reduction in knee extensor strength appears to occur in women through 2 mechanisms: one driven by pain (loss of specific strength) and one independent of pain (loss of muscle anatomic cross‐sectional area). Men who underwent knee replacement showed significantly reduced levels of extensor anatomic cross‐sectional area, but not significantly lower strength or specific strength. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 20, 2017 Category: Rheumatology Authors: Adam G. Culvenor, Felix C. Hamler, Jana Kemnitz, Wolfgang Wirth, Felix Eckstein Tags: Brief Report Source Type: research
Varicella zoster virus –specific T cell responses in untreated giant cell arteritis: comment on the article by England et al
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 20, 2017 Category: Rheumatology Authors: Marc B. Bigler, Julia R. Hirsiger, Mike Recher, Matthias Mehling, Thomas Daikeler, Christoph T. Berger Tags: Letters Source Type: research
A Phase IIb Trial of a Novel Extended ‐Release Microsphere Formulation of Triamcinolone Acetonide for Intraarticular Injection in Knee Osteoarthritis
ConclusionAlthough the primary end point was not met, our findings indicate a prolonged reduction in symptoms with FX006 with an evident dose response and a safety profile similar to saline placebo. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 20, 2017 Category: Rheumatology Authors: Philip G. Conaghan, Stanley B. Cohen, Francis Berenbaum, Joelle Lufkin, James R. Johnson, Neil Bodick Tags: Brief Report Source Type: research
Reply
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 20, 2017 Category: Rheumatology Authors: Bryant R. England, Ted R. Mikuls, Jeffrey R. Curtis Tags: Reply Source Type: research
Differences in Safety of Non ‐Steroidal Anti‐Inflammatory Drugs in Patients with Osteoarthritis and Rheumatoid Arthritis: A Randomized Clinical Trial
ConclusionsCelecoxib at approved dosages produced similar or lower cardiovascular, gastrointestinal, and renal risk for adverse events compared with ibuprofen and naproxen in OA and RA.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 20, 2017 Category: Rheumatology Authors: Daniel H. Solomon, M. Elaine Husni, Katherine E. Wolski, Lisa M. Wisniewski, Jeffrey S. Borer, David Y. Graham, Peter Libby, A. Michael Lincoff, Thomas F. L üscher, Venu Menon, Neville D. Yeomans, Qiuqing Wang, Weihang Bao, Manuela F. Berger, Steven E. N Tags: Full Length Source Type: research
A cross ‐sectional analysis of chikungunya arthritis patients 22‐months post‐infection demonstrate no detectable viral persistence in synovial fluid
ConclusionsThis is one of the largest observational studies involving synovial fluid analysis of chikungunya arthritis patients. Synovial fluid analysis revealed no detectable CHIKV. This finding suggests that CHIKV may cause arthritis through induction of potential host autoimmunity suggesting a role for immunomodulating medications in the treatment of CHIKV arthritis or that low‐level viral persistence exists in synovial tissue only that is undetectable in synovial fluid.This article is protected by copyright. All rights reserved. (Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 20, 2017 Category: Rheumatology Authors: Aileen Y. Chang, Karen A.O. Martins, Liliana Encinales, St. Patrick Reid, Marlon Acu ña, Carlos Encinales, Christian B. Matranga, Nelly Pacheco, Carlos Cure, Bhavarth Shukla, Teofilo Ruiz Arteta, Richard Amdur, Lisa H. Cazares, Melissa Gregory, Michael D Tags: Full Length Source Type: research
Reply
(Source: Arthritis and Rheumatism)
Source: Arthritis and Rheumatism - December 15, 2017 Category: Rheumatology Authors: Eric Marietta, Ashutosh Mangalam, Joseph Murray, Veena Taneja Tags: Reply Source Type: research
