Editorial Board
Publication date: March 2018Source: Arab Journal of Gastroenterology, Volume 19, Issue 1Author(s): (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
A note from the Editor’s desk
Publication date: March 2018Source: Arab Journal of Gastroenterology, Volume 19, Issue 1Author(s): (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Globular amyloidosis of the colon
Publication date: Available online 24 May 2018Source: Arab Journal of GastroenterologyAuthor(s): C. Díaz del Arco, M.J. Fernández AceñeroAbstractGastrointestinal involvement is frequent in systemic amyloidosis. However, amyloidosis can rarely be confined to the gastrointestinal tract or appear as a tumour mass. There have been few reports describing amyloid globular deposits in a variety of locations, as opposed to the usual linear ones. We herein report a rare case of globular amyloidosis involving the large bowel, which to the best of our knowledge is the second reported in the world literature.A 74-year-old man consu...
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Oxidative stress is bane in chronic liver diseases: Clinical and experimental perspective
Publication date: Available online 28 May 2018Source: Arab Journal of GastroenterologyAuthor(s): Devaraj EzhilarasanAbstractOxidative stress plays an important role in the pathogenesis of various chronic liver diseases (CLD) and increasing evidence have confirmed the contributory role of oxidative stress in the pathogenesis of drugs and chemical-induced CLD. Chronic liver injury is manifested as necrosis, cholestasis, fibrosis, and cirrhosis. Chronic administration of anti-tubercular, anti-retroviral, immunosuppressive drugs is reported to induce free radical generation during their biotransformation in the liver. Further,...
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Impact of Franseen needle on rapid onsite evaluation and histological examination following endoscopic ultrasonography-guided tissue acquisition in patients with splenic malignant lymphoma
Publication date: Available online 30 May 2018Source: Arab Journal of GastroenterologyAuthor(s): Tesshin Ban, Hiroshi Kawakami, Yoshimasa Kubota, Yuichiro SatoAbstractRapid onsite evaluation (ROSE) following endoscopic ultrasonography (EUS)-guided fine-needle aspiration contributes to the establishment of a diagnosis for various organs. Newly designed three-plane symmetric needles for EUS-guided fine-needle biopsy (EUS-FNB), such as the Franseen needle, have been developed to enable histological core tissue acquisition. However, EUS-guided tissue acquisition for hypervascular splenic lesions remains challenging. Tissue acq...
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Successful conservative treatment of type 3 injury (ductal injury) developing after ERCP
We present a case with successful conservative treatment of rare injury (type 3) developing after ERCP. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Acute lower gastrointestinal bleeding in Sudanese patients: a study on 301 patients in a specialized centre
ConclusionAcute lower gastrointestinal bleeding is common among elderly patients and the commonest cause is diverticular disease. Colonoscopy plays an important role in the diagnosis. Most patients respond to conservative therapy. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Treatment of PPI-resistant gastro-oesophageal reflux: A systematic review
ConclusionsA personalised choice of the best treatment for PPI-resistant GORD should be based on the results of an upper endoscopy and pH/MII monitoring. For patients in situations where the first line of treatment fails, we encourage the execution of trials for testing double doses of PPIs against alternative medicaments. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Psychiatric and functional neuroimaging abnormalities in chronic hepatitis C virus patients: Is vasculitis a contributing factor?
ConclusionsVasculitis may contribute to the development of neuropsychiatric involvement in HCV patients. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Rifaximin versus metronidazole in management of acute episode of hepatic encephalopathy: An open labeled randomized clinical trial
ConclusionRifaximin and metronidazole are equally effective in management of acute episode of overt HE, therefore, re-auditing of treatment protocols of HE are warranted especially in limited resource settings. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
The gut microbiome and irritable bowel syndrome: State of art review
Publication date: Available online 20 June 2018Source: Arab Journal of GastroenterologyAuthor(s): Ahmed E. Salem, Rajdeep Singh, Younan K. Ayoub, Ahmed M. Khairy, Gerard E. MullinAbstractIrritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal tract, the physiology of which is not very well understood. There are multiple factors and pathways involved in pathogenesis of this entity. Among all, dysmotility, dysregulation of the brain-gut axis, altered intestinal microbiota and visceral hypersensitivity play a major role. Over the last years, research has shown that the type of gut microbiome present in...
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Hepatitis C virus antibodies are absent among high risk group of health care workers in Damascus Hospital
ConclusionHCV is not a main issue regarding its prevalence among HCWs in Damascus Hospital. Nevertheless, it is still necessary to develop a mandatory well-organized program to increase the awareness among HCWs and develop stricter prevention policies especially about bloodborne diseases transmitted occupationally. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
In vivo identification of novel TGIF2LX target genes in colorectal adenocarcinoma using the cDNA-AFLP method
ConclusionDownregulation of Nir1 and upregulation of Nir2 and FHIT genes due to the overexpression of TGIF2LX suggests that the gene plays an important role as a suppressor in colorectal adenocarcinoma. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
In vivo identification of novel TGIF2LX target genes in colorectal adenocarcinoma using the cDNA-AFLP method
Conclusion Downregulation of Nir1 and upregulation of Nir2 and FHIT genes due to the overexpression of TGIF2LX suggests that the gene plays an important role as a suppressor in colorectal adenocarcinoma. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - June 29, 2018 Category: Gastroenterology Source Type: research
Treatment of PPI-resistant gastro-oesophageal reflux: A systematic review
Conclusions A personalised choice of the best treatment for PPI-resistant GORD should be based on the results of an upper endoscopy and pH/MII monitoring. For patients in situations where the first line of treatment fails, we encourage the execution of trials for testing double doses of PPIs against alternative medicaments. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - June 21, 2018 Category: Gastroenterology Source Type: research
