Psychiatric and functional neuroimaging abnormalities in chronic hepatitis C virus patients: Is vasculitis a contributing factor?
ConclusionsVasculitis may contribute to the development of neuropsychiatric involvement in HCV patients. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Rifaximin versus metronidazole in management of acute episode of hepatic encephalopathy: An open labeled randomized clinical trial
ConclusionRifaximin and metronidazole are equally effective in management of acute episode of overt HE, therefore, re-auditing of treatment protocols of HE are warranted especially in limited resource settings. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
The gut microbiome and irritable bowel syndrome: State of art review
Publication date: Available online 20 June 2018Source: Arab Journal of GastroenterologyAuthor(s): Ahmed E. Salem, Rajdeep Singh, Younan K. Ayoub, Ahmed M. Khairy, Gerard E. MullinAbstractIrritable bowel syndrome (IBS) is a functional disorder of the gastrointestinal tract, the physiology of which is not very well understood. There are multiple factors and pathways involved in pathogenesis of this entity. Among all, dysmotility, dysregulation of the brain-gut axis, altered intestinal microbiota and visceral hypersensitivity play a major role. Over the last years, research has shown that the type of gut microbiome present in...
Source: Arab Journal of Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
Hepatitis C virus antibodies are absent among high risk group of health care workers in Damascus Hospital
ConclusionHCV is not a main issue regarding its prevalence among HCWs in Damascus Hospital. Nevertheless, it is still necessary to develop a mandatory well-organized program to increase the awareness among HCWs and develop stricter prevention policies especially about bloodborne diseases transmitted occupationally. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
In vivo identification of novel TGIF2LX target genes in colorectal adenocarcinoma using the cDNA-AFLP method
ConclusionDownregulation of Nir1 and upregulation of Nir2 and FHIT genes due to the overexpression of TGIF2LX suggests that the gene plays an important role as a suppressor in colorectal adenocarcinoma. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 10, 2018 Category: Gastroenterology Source Type: research
The effect of premedication with peppermint oil capsules (Colpermin) prior to colonoscopy: A double blind randomized placebo-controlled trial
ConclusionThis randomized controlled trial does not support the routine use of peppermint oil capsules prior to colonoscopy as a tool for procedure optimization, and patients’ and endoscopist’s satisfaction. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
A difficult diagnosis of coeliac disease: Repeat duodenal histology increases diagnostic yield in patients with concomitant causes of villous atrophy
We report a case of a woman with anaemia, weight loss and diarrhoea with an initial diagnosis of seronegative CD and a histological documented villous atrophy who did not improve on gluten-free diet due to the concomitant presence of common variable immunodeficiency (CVID) and Giardia lamblia infection. This case report confirms that CD diagnosis in CVID patients is difficult; the combination of anti-endomysial antibodies (EmA-IgA), anti-tissue transglutaminase antibodies (tTG-IgAb) antibodies and total IgA is obligatory in basic diagnostic of CD but in CVID are negative. Furthermore, the typical histological aspects of th...
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Gastric submucosal haematoma caused by an amyloidoma in the setting of multiple myeloma
Publication date: December 2017Source: Arab Journal of Gastroenterology, Volume 18, Issue 4Author(s): Stella C. Pak, John-Phillip T. MarkovicAbstractThis is a case of a 67-year-old woman with a history of multiple myeloma with amyloidosis who presented with massive hematemesis. Emergent upper endoscopy revealed a mass on the greater curvature of the stomach, which measured approximately 3 cm in width and 7 cm in length. The patient underwent a wedge resection of the gastric mass without complication. Microscopic examination of the gastric mass revealed amorphous deposits that were congophilic in nature and stained posi...
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Value of water enema computed tomography in elderly symptomatic patients
ConclusionWater enema computed tomography has proven to be a valuable and non-invasive method indicated as a first-line examination in case of colonic symptoms in the elderly to diagnose supra-centimetric lesions. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Sustained improvement of psoriasis associated with HCV after virologic response to sofosbuvir/ribavirin
Publication date: December 2017Source: Arab Journal of Gastroenterology, Volume 18, Issue 4Author(s): Asem Ahmed ElfertAbstractAn 18 year old boy attended a dermatology clinic outside our hospital and diagnosed with psoriasis. His skin lesions over both ankles (Fig. 1) did not improve at all with potent local steroids twice for 3 months, then 3 times daily for another 3 months. His dermatologist talked to him about using methotrexate and asked for liver function tests before starting the systemic therapy.His ALT and AST were doubled. The patient came to our Hepatology clinic worried about his elevated liver enzymes. ...
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Double-balloon enteroscopy (DBE) in patients presenting with obscure gastrointestinal bleeding (OGIB)
ConclusionDBE is an excellent endoscopic procedure that has a relatively high diagnostic and therapeutic yield. The procedure is feasible and exhibits a high safety profile with a low complication rate when performed by an experienced endoscopist. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
A note from the Editor’s desk
Publication date: December 2017Source: Arab Journal of Gastroenterology, Volume 18, Issue 4Author(s): (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Prevalence and risk factors of hepatitis D virus infection in patients with chronic hepatitis B infection attending the three main tertiary hospitals in Libya
ConclusionAlthough the study demonstrated that Libya has low to moderate prevalence of HDV (2,5%), it is important for policy makers and health care providers to continue the preventive measures for HDV spread, and HBV prevention program including utilization of HBV vaccine. Furthermore, it is imperative to screen chronic HBV patients for HDV for close observation for early diagnosis of subsequent development of liver cirrhosis. Moreover, further epidemiologic and genetic studies are needed to explore the trend for HDV infection in Libya. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Establishing ultrasound based transient elastography cutoffs for different stages of hepatic fibrosis and cirrhosis in Egyptian chronic hepatitis C patients
ConclusionTransient elastography performs well for significant hepatic fibrosis, advanced hepatic fibrosis and cirrhosis, with validated cut-offs of 7.1, 9 and 12.2 kPa, respectively, in genotype 4 CHC patients. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
Antibacterial resistance patterns of extended spectrum β-lactamase -producing enteropathogenic Escherichia coli strains isolated from children
ConclusionsThe study revealed that 79.7% of EPEC isolates from Iranian children were ESBL-producing and were comparable with the non ESBL-producing isolates regarding susceptibility to the antibiotics. (Source: Arab Journal of Gastroenterology)
Source: Arab Journal of Gastroenterology - July 5, 2018 Category: Gastroenterology Source Type: research
