Plasma temperature during methylene blue/light treatment influences virus inactivation capacity and product quality
ConclusionsTemperature conditions for THERAFLEX MB‐Plasma treatment must be carefully controlled to assure uniform quality of pathogen‐reduced plasma in routine production. Inactivation of cooled plasma is not recommended. (Source: Vox Sanguinis)
Source: Vox Sanguinis - February 1, 2018 Category: Hematology Authors: U. Gravemann, W. Handke, C. Sumian, I. Alvarez, S. Reichenberg, T. H. M üller, A. Seltsam Tags: Original Paper Source Type: research
Variation in red cell transfusion decisions in the intensive care unit – a nationwide survey in the Netherlands
ConclusionsPhysicians decided differently on red‐blood‐cell transfusion given the clinical scenarios and weighed clinical characteristics differently in their transfusion decisions. These findings suggest there still is substantial variation in critical care transfusion practice. (Source: Vox Sanguinis)
Source: Vox Sanguinis - February 1, 2018 Category: Hematology Authors: F. J. Kranenburg, S. A. Willems, S. Le Cessie, P. J. Marang ‐van de Mheen, J. G. Bom, M. S. Arbous Tags: Original Paper Source Type: research
Transfusion ‐transmitted hepatitis B virus (HBV) infection from an individual‐donation nucleic acid (ID‐NAT) non‐reactive donor
Lookback was initiated upon notification of an acute HBV infection in a repeat Irish donor, 108 days post‐donation. The donation screened non‐reactive by individual‐donation nucleic acid testing (ID‐NAT) using the Procleix Ultrio Elite multiplex assay and again when the archived sample was retested, but the discriminatory assay for HBV was reactive. The immunocompromised recipient of the implicated red cell component was tested 110 days post‐transfusion, revealing a HBV DNA viral load of 470 IU/ml. Genotype C2 sequences identical across two regions of the HBV genome were found in samples from the donor and rec...
Source: Vox Sanguinis - February 1, 2018 Category: Hematology Authors: N. O'Flaherty, I. Ushiro ‐Lumb, L. Pomeroy, S. Ijaz, F. Boland, C. De Gascun, J. Fitzgerald, J. O'Riordan Tags: Case Report Source Type: research
Targeted recruitment of male donors for allogeneic haematopoietic cell transplantation: A review of the evidence
Vox Sanguinis, EarlyView. (Source: Vox Sanguinis)
Source: Vox Sanguinis - January 22, 2018 Category: Hematology Source Type: research
Creutzfeldt ‐Jakob disease and blood transfusion safety
Vox Sanguinis, EarlyView. (Source: Vox Sanguinis)
Source: Vox Sanguinis - January 22, 2018 Category: Hematology Source Type: research
A high plasma: red blood cell transfusion ratio during liver transplantation is associated with decreased blood utilization
Vox Sanguinis, EarlyView. (Source: Vox Sanguinis)
Source: Vox Sanguinis - January 22, 2018 Category: Hematology Source Type: research
Investigation of antibody to severe fever with thrombocytopenia syndrome virus (SFTSV) in blood samples donated in a SFTS ‐endemic area in Japan
Vox Sanguinis, EarlyView. (Source: Vox Sanguinis)
Source: Vox Sanguinis - January 22, 2018 Category: Hematology Source Type: research
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Vox Sanguinis, Ahead of Print. (Source: Vox Sanguinis)
Source: Vox Sanguinis - January 22, 2018 Category: Hematology Source Type: research
Investigation of antibody to severe fever with thrombocytopenia syndrome virus (SFTSV) in blood samples donated in a SFTS ‐endemic area in Japan
The risk of transfusion‐transmitted infection (TTI) for severe fever with thrombocytopenia syndrome virus (SFTSV) is a concern because person‐to‐person transmission resulting from contact with SFTSV‐contaminated blood has been reported. To obtain information regarding the risk of TTI‐SFTSV, antibody testing was performed for blood samples donated in an severe fever with thrombocytopenia syndrome‐endemic area in Japan. No antibody‐positive samples were detected among 3990 samples. This finding suggested that there were few cases of SFTSV infection among donors and that the risk of TTI‐SFTSV was also estimate...
Source: Vox Sanguinis - January 22, 2018 Category: Hematology Authors: C. Matsumoto, N. Shinohara, R. A. Furuta, N. Tanishige, M. Shimojima, K. Matsubayashi, T. Nagai, K. Tsubaki, M. Satake Tags: Short Report Source Type: research
Creutzfeldt ‐Jakob disease and blood transfusion safety
Transmissible spongiform encephalopathies (TSEs) are untreatable, fatal neurologic diseases affecting mammals. Human disease forms include sporadic, familial and acquired Creutzfeldt‐Jakob disease (CJD). While sporadic CJD (sCJD) has been recognized for near on 100 years, variant CJD (vCJD) was first reported in 1996 and is the result of food‐borne transmission of the prion of bovine spongiform encephalopathy (BSE, ‘mad cow disease’). Currently, 230 vCJD cases have been reported in 12 countries, the majority in the UK (178) and France (27). Animal studies demonstrated highly efficient transmission of natural scrap...
Source: Vox Sanguinis - January 22, 2018 Category: Hematology Authors: C. R. Seed, P. E. Hewitt, R. Y. Dodd, F. Houston, L. Cervenakova Tags: Review Article Source Type: research
Targeted recruitment of male donors for allogeneic haematopoietic cell transplantation: A review of the evidence
Many patients in need of a haematopoietic cell transplant cannot find a suitable HLA‐compatible donor within their families and rely on volunteers who have registered as haematopoietic stem cell donors with a stem cell donor registry. Transplant physicians mostly prefer male donors for their patients when multiple donor options exist, and organizations recruiting donors are actively targeting males in their recruitment efforts. However, significant recruitment of female donors continues worldwide and appears to be increasing. In this review, the evidence underlying transplant physician preference for male donor selection...
Source: Vox Sanguinis - January 22, 2018 Category: Hematology Authors: W. Fingrut, K. Rikhraj, D. Allan Tags: Review Article Source Type: research
Diary of Events
(Source: Vox Sanguinis)
Source: Vox Sanguinis - January 19, 2018 Category: Hematology Tags: Diary of Events Source Type: research
