High expression of apoptosis-inducing factor, mitochondrion-associated 3 (AIFM3) in human cholangiocarcinoma
In conclusion, AIFM3 was aberrantly expressed only in the mitochondria of CCA tissues. This finding suggests that AIFM3 could be a potential target molecule for CCA chemotherapy. < /p > (Source: Tumor Biology)
Source: Tumor Biology - July 28, 2016 Category: Cancer & Oncology Source Type: research
Prognostic value of mixed lineage kinase domain-like protein expression in the survival of patients with gastric caner
In conclusion, our findings provide evidence that MLKL might serve as a candidate tumor suppressor and a potential prognostic biomarker for GC. < /p > (Source: Tumor Biology)
Source: Tumor Biology - July 28, 2016 Category: Cancer & Oncology Source Type: research
Erratum to: Secretome of tumor-associated leukocytes augment epithelial-mesenchymal transition in positive lymph node breast cancer patients via activation of EGFR/Tyr845 and NF-kB/p65 signaling pathway
(Source: Tumor Biology)
Source: Tumor Biology - July 28, 2016 Category: Cancer & Oncology Source Type: research
Association of variants in BAFF (rs9514828 and rs1041569) and BAFF-R (rs61756766) genes with the risk of chronic lymphocytic leukemia
In conclusion, our results indicate that SNPs in < em class= " a-plus-plus " > BAFF < /em > and < em class= " a-plus-plus " > BAFF-R < /em > genes may be considered as potential CLL risk factors. < /p > (Source: Tumor Biology)
Source: Tumor Biology - July 28, 2016 Category: Cancer & Oncology Source Type: research
Biomarkers of genome instability and cancer epigenetics
< h3 class= " a-plus-plus " > Abstract < /h3 > < p class= " a-plus-plus " > Tumorigenesis is a multistep process involving genetic and epigenetic alterations that drive somatic evolution from normal human cells to malignant derivatives. Collectively, genetic and epigenetic alterations might be combined into biomarkers for the assessment of risk, the detection of early stage tumors, and accurate tumor characterization before and after treatment. Recent efforts have provided systematic approaches to cancer genomics through the application of massive sequencing of specific tumor types. Here, we review biomarkers of genome ins...
Source: Tumor Biology - July 27, 2016 Category: Cancer & Oncology Source Type: research
