Is leptin receptor gene (Gln223Arg) polymorphism associated with disease susceptibility and severity in patients of primary knee osteoarthritis?
ConclusionLeptin receptor gene (Gln223Arg) SNP might be associated with severity of KOA. There is a significant genetic association between the SNP and BMI hence, LEPR SNP might be indirectly associated with the incidence of KOA. Furthermore, the SNP is not directly associated with KOA susceptibility in the Egyptian population. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - May 7, 2019 Category: Rheumatology Source Type: research
Association of interleukin-17 with peripheral spondyloarthropathic changes detected by musculoskeletal ultrasound in psoriatic patients
ConclusionMSUS proved valuable, simple and non-invasive tool in early detection of enthesopathy and subclinical arthritis in psoriatic patients. Association of elevated serum level of IL-17 with MSUS findings clarifies its potential role in developing musculoskeletal complaints in psoriatic patients. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - May 3, 2019 Category: Rheumatology Source Type: research
Is it useful to measure serum ferritin level in systemic lupus erythematosus patients?
ConclusionSerum ferritin is elevated significantly in SLE patients especially those with severe activity. A remarkable difference in serum ferritin levels in patients with hematological manifestations was found making it a potentially useful inflammatory marker for disease activity in patients with blood dyscrasia. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 26, 2019 Category: Rheumatology Source Type: research
Primary biliary cholangitis in patients with systemic sclerosis: Unmasking the true face of Reynold's syndrome
ConclusionAutoantibodies may provide information about organ involvement in SSc. AMA, AMA-M2, and ACA may predict hepatic disease in asymptomatic SSc patients with elevated GGT levels. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 25, 2019 Category: Rheumatology Source Type: research
The incremental value of ultrasound in detection of subclinical peripheral enthesitis in patients with spondyloarthritis
ConclusionUltrasonography is superior to clinical examination in detection of enthesitis in SpA patients with good sensitivity and specificity. Enthesitis is common in upper limbs as it is in lower limbs; pathological findings and predictive values of calcifications and erosions were high at entheses of upper limbs especially supraspinatus. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 24, 2019 Category: Rheumatology Source Type: research
Editorial Board
Publication date: April 2019Source: The Egyptian Rheumatologist, Volume 41, Issue 2Author(s): (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 23, 2019 Category: Rheumatology Source Type: research
Diagnostic value and clinical significance of anti-carbamylated protein (anti-CarP) antibodies in Egyptian patients with rheumatoid arthritis
ConclusionThe sensitivity of anti-CarP antibodies was low in comparison to both RF and anti-CCP; however, they showed high specificity and were detected in anti-CCP negative patients, so they could be useful to test beside anti-CCP and RF. Anti-CarP antibodies may reflect disease radiological damage. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 23, 2019 Category: Rheumatology Source Type: research
Juvenile-onset mixed connective tissue disease associated with macrophage activation syndrome: A case with refractory Raynaud’s phenomenon
ConclusionMCTD may present with a myriad of rheumatic manifestations and in association with MAS the diagnosis and management may be challenging. Refractory Raynauds’ phenomenon may remarkably improve on transthoracic sympathectomy. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 16, 2019 Category: Rheumatology Source Type: research
Anti-neutrophil cytoplasmic antibody (ANCA)-associated scleritis: A diagnostic challenge and outcome
ConclusionANCA-associated vasculitis can have atypical ocular presentation and can be clinically misdiagnosed as conjunctivitis. Long term visual and systemic complications can be prevented with early detection and prompt immunosuppressive treatment. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 14, 2019 Category: Rheumatology Source Type: research
Lymphopenia in systemic lupus erythematosus patients: Is it more than a laboratory finding?
ConclusionLymphopenia is a common finding in SLE patients and was significantly associated with lupus nephritis, complement consumption, higher steroid doses and cyclophosphamide administration. Lymphopenia might be a promising marker for renal involvement in SLE. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 14, 2019 Category: Rheumatology Source Type: research
Nail fold capillaroscopic changes in Egyptian patients with psoriatic arthritis in comparison to rheumatoid arthritis
ConclusionThe nailfold capillaroscopy in RA patients had no specific changes, While in PsA patients showed low density, dilated, tortuous and disorganized capillaries and hemorrhages. So, Nailfold capillaroscopy can be used in the differentiation between both diseases. NFC abnormalities may be related to the disease activity. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 9, 2019 Category: Rheumatology Source Type: research
Elevated Cytomegalovirus and Epstein-Barr virus burden in rheumatoid arthritis: A true pathogenic role or just a coincidence
ConclusionsA high incidence of CMV and EBV was detected in RA patients with increased viral load than described previously. Frequencies of RA disease manifestations are significantly higher in CMV infected patients compared to those infected with EBV. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - April 3, 2019 Category: Rheumatology Source Type: research
Does the use of electronic devices provoke the carpal tunnel syndrome (CTS) symptoms and functional impairment? A cross-sectional study
ConclusionThere was no significant association between the patterns of electronic devices use and CTS symptoms. The high prevalence of CTS symptoms necessitates awareness programs, especially among the young population. Although this work did not prove the association, further studies with confirmatory clinical testing are recommended. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - March 19, 2019 Category: Rheumatology Source Type: research
Editorial Board
Publication date: January 2019Source: The Egyptian Rheumatologist, Volume 41, Issue 1Author(s): (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - March 17, 2019 Category: Rheumatology Source Type: research
Calcaneal intraosseous lipoma: A rare cause of heel pain
ConclusionCalcaneal lipoma should be mentioned as a forerunner among the differential diagnoses of persistent heel pain and promptly dealt with for a promising outcome. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - February 7, 2019 Category: Rheumatology Source Type: research
