Do acid suppressive drugs (pantoprazole and ranitidine) attenuate the protective effect of alendronate in estrogen-deficient osteoporotic rats?
ConclusionRanitidine proved safer than pantoprazole for patients with high risk of osteoporosis and in alendronate-treated patients. Clinicians should carefully judge the indication of use of acid suppressing medications in osteoporotic patients. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Comparing D-dimer status in children with familial Mediterranean fever during and in between acute attacks
ConclusionD-dimer was significantly positive in FMF patients compared to control. These results raise the possibility of thrombosis in FMF patients regardless the presence or absence of acute attack. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Diagnostic value of anti-annexin A5 antibodies in seropositive versus seronegative antiphospholipid syndrome patients
Conclusion: anti-annexinA5 antibodies are promising for detecting obstetric and thrombotic morbidity in both SP- and sN-APS patients. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Quality of life in Turkish patients with Familial Mediterranean Fever: Association with fatigue, psychological status, disease severity and other clinical parameters
Conclusion: QoL is associated with fatigue, depression and disease severity in FMF patients. It should be used in routine clinical evaluation as an outcome measure in FMF. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Atlantoaxial instability: An exceptional complication of ankylosing spondylitis
ConclusionOdontoid pannus formation is rare in AS. Clinical and radiological follow-up are important to assess the impact on the cervical spine. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Osteonecrosis of the femoral head among rheumatology patients in Kara (Togo)
ConclusionONFH is frequent in northern Togo and sickle cell disease is the main risk factor. An important part of evolved forms is noted in relation with a diagnostic delay. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Complete form pachydermoperiostosis in Tunisia – A case series and literature review
ConclusionsComplete form of primary PDP is rarely present among rheumatic diseases patients in Tunisia. A multicenter larger number longitudinal study is recommended. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Antinucleosome antibodies in systemic lupus erythematosus patients: Relation to disease activity and lupus nephritis
ConclusionAnti-NSC antibodies could be a useful addition to the laboratory tests that can help in the diagnosis of SLE. Also, it has a significant association to photosensitivity but no relation to with disease activity or renal involvement. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Assessment of vascular endothelial growth factor in systemic lupus erythematosus patients with anti-phospholipid syndrome
Conclusion: Serum VEGF was remarkably increased in SLE patients with no special relation to APS and may be considered a potential marker of disease activity. Further insights on its relation with anti-ds DNA and genotypic expression in SLE are warranted. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Diagnostic potential of high resolution ultrasound and nerve conduction study in patients with idiopathic carpal tunnel syndrome
ConclusionsThere was an insignificant difference between nerve conduction study and high resolution ultrasound in diagnosis of idiopathic CTS. However, high resolution ultrasound had a superior diagnostic utility in CTS, and is valuable for exclusion of secondary CTS and anatomical variants of the median nerve. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Clinical significance of endocan in Behçet’s disease patients: A potential marker of disease activity
ConclusionSerum endocan may serve as a potential marker of disease activity in BD. Patients with genital ulcers, papulopastular lesions and arthritis showed higher serum endocan levels. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Clinical significance of serum B cell chemokine (CXCL13) in early rheumatoid arthritis patients
ConclusionCXCL13 is an important for the diagnosis of early RA with a superior diagnostic performance compared to RF and anti-CCP. It may also be considered a potential biomarker of disease activity. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Osteoarthritis knee hip quality of life questionnaire assessment in Egyptian primary knee osteoarthritis patients: Relation to clinical and radiographic parameters
Conclusion: Egyptian patients with primary KOA have relatively poor HRQoL; reflected mainly by pain component of the OAKHQoL questionnaire. Disease duration and bilaterality were predictors for lower scores of all questionnaire domains, knee stiffness for four subscales. Hypertension, knee deformity and K-L classification were good predictors for lower scores of two subscales. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Vascular endothelial growth factor and colour Doppler ultrasonography in knee osteoarthritis: Relation to pain and physical function
ConclusionSerum and synovial VEGF correlated with clinical, functional, radiographic and US severity in KOA patients. Both VEGF and musculoskeletal ultrasound may serve as promising potential tools for evaluating disease severity in KOA. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Behçet’s disease patterns and subsets in a cohort of Egyptian patients
ConclusionBD usually affects the same system throughout the disease course whether mucocutaneous, vascular, ocular or neurological and the most common pattern is the one system affection. This will help to predict the system that will be affected in each time the patient presents with a disease relapse. Also, it will help in differentiation between disease relapse and any associated other disease minimizing the need for and the cost of investigations. However, future studies on larger number of patients are recommended. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
