Vascular cell adhesion molecule-1 (VCAM-1), flow mediated dilatation (FMD) and carotid intima media thickness (IMT) in children with juvenile idiopathic arthritis: Relation to disease activity, functional status and fatigue
ConclusionJIA patients had impaired endothelial function and increased cIMT with increased sVCAM-1, impaired lipid profile, decreased physical activity and increased fatigue with a potentially higher cardiovascular risk in this pediatric population. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Role of musculoskeletal ultrasonography in the detection of subclinical synovitis in oligo and polyarticular juvenile idiopathic arthritis children
ConclusionMSUS is superior to clinical examination in early detection of synovitis. It is a reliable method for disease activity assessment in JIA patients, so it can be used in association with standard clinical examination for better classification, diagnosis, treatment strategy and prognosis of JIA subtypes. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Serum ferritin, transferrin and metabolic syndrome are risk factors for subclinical atherosclerosis in Egyptian women with systemic lupus erythematosus (SLE)
ConclusionMetS in SLE is a associated with accelerated atherosclerosis while serum ferritin and transferrin are strong indicators of SLE activity and damage. Considering the association with MetS and measuring the cIMT in SLE patients is recommended and provides a useful marker for detecting subclinical cases and predicting future cardiovascular events. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Peptidyl-arginine deiminase-type IV as a diagnostic and prognostic marker in rheumatoid arthritis patients
ConclusionSerum PADI4 was diagnostic for RA and comparable with anti-CCP. It correlated with disease activity and could be a promising follow up marker of remission. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Performance of serum adenosine deaminase in measuring disease activity in rheumatoid arthritis patients
ConclusionIntegration of sADA in the DAS28 index can be a useful marker that reflects RA activity. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Critically ill systemic lupus erythematosus patients referred to the intensive care unit of Fayoum University Hospital: Frequency, complications and outcome
ConclusionSLE patients admitted to the ICU are at an increased risk of mortality especially those with high disease activity. The main causes of mortality were infection, respiratory, cardiac and neurological complications. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Unusual CD4+CD28− T lymphocyte subset is implicated in the pathogenesis of early atherosclerosis in patients with rheumatoid arthritis
ConclusionCD4+CD28− cells may contribute to the development of premature atherosclerosis in RA patients. Further studies are recommended to evaluate the benefit of CD4+CD28− T-cell modulation on the future development of atherosclerosis in these patients. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Ultrasound-guided injection of platelet rich plasma versus corticosteroid for treatment of rotator cuff tendinopathy: Effect on shoulder pain, disability, range of motion and ultrasonographic findings
ConclusionsBoth PRP and corticosteroid injections were effective in the treatment of RCT. PRP is a safe and good alternative to corticosteroid injection that promotes healing and decreases inflammation. Ultrasound-guided injection may increase the efficacy. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Clinical characteristics and health related quality of life (HRQoL) in Egyptian patients with systemic lupus erythematosus
ConclusionsSLE is a condition associated with high unmet need and considerable burden to patients. To our knowledge, no previous study has systematically examined the clinical features as well as HRQoL of SLE patients in Sharkia Governorate, Eastern Egypt. HRQoL is a multidimensional concept that encompasses physical, emotional and social components associated with SLE manifestations. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 10, 2018 Category: Rheumatology Source Type: research
Factors leading to work absenteeism in Tunisian ankylosing spondylitis patients
ConclusionAbsenteeism is high amongst Tunisian AS patients. Work conditions were important factors of absenteeism in Tunisian AS patients that directly influence productivity. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 5, 2018 Category: Rheumatology Source Type: research
Acute severe cutaneous methotrexate toxicity in a patient with rheumatoid arthritis: Report of a rare side effect
Conclusion: Although MTX is an option of great therapeutic value for RA. Rheumatologists and Dermatologists need to be alert to the possibility of cutaneous adverse events associated with MTX therapy. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 5, 2018 Category: Rheumatology Source Type: research
Diagnostic value of salivary gland ultrasonography for Sjӧgren's syndrome in patients with sicca symptoms
ConclusionSGUS is a noninvasive method with high diagnostic value for diagnosis of primary and secondary SS. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 5, 2018 Category: Rheumatology Source Type: research
The effectiveness of etanercept and adalimumab on anemia of chronic disease and serum hepcidin in patients with rheumatoid arthritis, a comparative study
ConclusionsTreatment with etanercept or adalimumab plus MTX significantly improved ACD in RA patients without significant differences between them. Serum hepcidin is a potential indicator for anemia of chronic disease and disease activity in RA patients. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 5, 2018 Category: Rheumatology Source Type: research
Serum serotonin in rheumatoid arthritis patients: Relation to rheumatoid factor positivity, clinical manifestations and fibromyalgia
ConclusionSerum serotonin level was high in RA, especially in seropositive patients. It demonstrated central antidepressant and peripheral pro-inflammatory role. The SSRI could be of benefit only in RA with FMS. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 5, 2018 Category: Rheumatology Source Type: research
Ultrasonographic evaluation of haemodynamic flow changes to the hip in systemic lupus erythematosus patients: Correlation with risk factors for osteonecrosis
ConclusionThe presence of associated risk factors for ON contributes to haemodynamic flow changes. Color Doppler ultrasound represents a useful tool for the assessment and follow-up for haemodynamic deterioration of hip vascularity in both hip joints. (Source: The Egyptian Rheumatologist)
Source: The Egyptian Rheumatologist - July 5, 2018 Category: Rheumatology Source Type: research
