Issue Information
(Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 30, 2017 Category: Allergy & Immunology Tags: Issue Information Source Type: research
In Response to ‘Chemokine Patterns in Children with Acute Bacterial Infections’
(Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 22, 2017 Category: Allergy & Immunology Authors: A. K. Vyas, Nirupma Trehanpati Tags: Letter to the Editor Source Type: research
Association Between TNF ‐α Promoter −308 A/G Polymorphism and Systemic Lupus Erythematosus Susceptibility: A Case–Control Study and Meta‐Analysis
Abstract
The tumour necrosis factor‐α (TNF‐α) promoter −308 A/G polymorphism plays an important role in the aetiology of systemic lupus erythematosus (SLE). Several studies have estimated the association between TNF‐α −308 A/G and SLE risk. However, results were inconsistent. A case–control study was carried out to explore the association between TNF‐α −308 A/G and the SLE risk in a Chinese Han population. Meta‐analysis combining present with previous studies was conducted to further explore the association. Our case–control study included 556 patients with SLE along with 570 matched healthy control...
Source: Scandinavian Journal of Immunology - March 22, 2017 Category: Allergy & Immunology Authors: Z. ‐C. Yang, F. Xu, M. Tang, X. Xiong Tags: Human Immunology Source Type: research
Experimental Arthritis in the Rat Induced by the Superantigen Staphylococcal Enterotoxin A
Abstract
The pathogenesis of rheumatoid arthritis (RA) is incompletely understood. Human endogenous retroviruses (HERVs) and their superantigenic envelope protein (env) have been implicated in the pathogenesis of RA. In the present investigation, the arthritogenic potential of the superantigen staphylococcal enterotoxin A (SEA) has been investigated. In the present investigation, the bacterial superantigen staphylococcal enterotoxin A (SEA) was injected into the right knee joint of 15 Lewis rats. Further nine animals received saline. Animals were sacrificed one, five and 10 days after the injection, respectively. The anti...
Source: Scandinavian Journal of Immunology - March 22, 2017 Category: Allergy & Immunology Authors: K. Gerlach, C. Tomuschat, R. Finke, M. S. Staege, C. Br ütting, J. Brandt, B. Jordan, R. Schwesig, A. Rosemeier, K.‐S. Delank, M. E. Kornhuber, A. Emmer Tags: Experimental Immunology Source Type: research
Immune Regulation by T Regulatory Cells in Hepatitis B Virus ‐Related Inflammation and Cancer
Abstract
Hepatocellular carcinoma (HCC) is the leading cause of cancer death, and hepatitis B virus (HBV) infection is one of the commonest causes in Asian countries. India has the second largest pool after China for hepatitis B‐infected subjects. HBV clearance is T cell dependent, and one of the reasons for T cells hyporesponsiveness is due to mass production of regulatory T cells (Tregs) through activation of Notch signalling, which suppress CD4/CD8 T cells. Tregs are important to maintain cellular homoeostasis; however, during viral infection increase of Tregs is inversely proportional to HBV DNA titres. Tregs exert t...
Source: Scandinavian Journal of Immunology - March 22, 2017 Category: Allergy & Immunology Authors: N. Trehanpati, A. K. Vyas Tags: Review Source Type: research
Announcement
(Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 22, 2017 Category: Allergy & Immunology Tags: Announcement Source Type: research
Issue Information
(Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 22, 2017 Category: Allergy & Immunology Tags: Issue Information Source Type: research
PTEN/PI3k/AKT regulates macrophage polarization in emphysematous mice
In conclusion, we confirmed that macrophage M2 polarization was induced in emphysematous mice generated by CS exposure combined with intraperitoneal injection of CSE. We also showed that M2 polarization was mediated through PTEN/PI3k/AKT pathway activation.
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 7, 2017 Category: Allergy & Immunology Authors: JunJuan Lu, LiHua Xie, Chun Liu, Qiang Zhang, ShengHua Sun Tags: Regular Article Source Type: research
Computational prediction of Usutu virus E protein B ‐cell and T‐cell epitopes for potential vaccine development
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 7, 2017 Category: Allergy & Immunology Authors: Navaneethan Palanisamy, Johan Lennerstrand Tags: Regular Article Source Type: research
The 44th Annual Meeting of the Scandinavian Society of Immunology
(Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 1, 2017 Category: Allergy & Immunology Tags: Announcement Source Type: research
Evaluation of Oxidative Stress and Antioxidant Status in Chronic Obstructive Pulmonary Disease
This study suggests that oxidant and antioxidant imbalance plays an important role in various stages of severity of COPD. These results revealed the presence of an oxidative stress in subjects with COPD, and it is proportionate to the severity of disease. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 1, 2017 Category: Allergy & Immunology Authors: S. Singh, S. K. Verma, S. Kumar, M. K. Ahmad, A. Nischal, S. K. Singh, R. K. Dixit Tags: Human Immunology Source Type: research
Analysis of miR ‐146a and miR‐142‐3p as Potential Markers of Freshly Isolated or In Vitro‐Expanded Human Treg cells
Abstract
Regulatory CD4+ T cells (Tregs) are pivotal for prevention of autoimmunity. The use of Tregs is therefore of increasing interest in in vitro drug screening assays as well as for a cytotherapy per se against autoimmune disorders. For both purposes, in vitro expansion of peripheral blood Tregs is necessary and there is an increasing need to identify novel markers that can discriminate natural thymic‐derived Tregs (tTregs) from other T cell subsets, and ideally, such markers should be stably expressed during in vitro expansion procedures. We screened for novel miRNAs differentially expressed in tTregs and identi...
Source: Scandinavian Journal of Immunology - March 1, 2017 Category: Allergy & Immunology Authors: K. Holmstr øm, A. E. Pedersen, M. Gad Tags: Experimental Immunology Source Type: research
CD6 and Linker of Activated T Cells are Potential Interaction Partners for T Cell ‐Specific Adaptor Protein
Abstract
The T cell‐specific adaptor protein (TSAd) contains several protein interaction domains, and is merging as a modulator of T cell activation. Several interaction partners for the TSAd proline‐rich region and phosphotyrosines have been identified, including the Src and Tec family kinases lymphocyte‐specific protein tyrosine kinase and interleukin 2‐inducible T cell kinase. Via its Src homology 2 (SH2) domain, TSAd may thus function as a link between these enzymes and other signalling molecules. However, few binding partners to the TSAd SH2 domain in T cells are hitherto known. Through the use of in silico li...
Source: Scandinavian Journal of Immunology - March 1, 2017 Category: Allergy & Immunology Authors: C. D. Hem, M. Ekornhol, S. Granum, V. Sundvold ‐Gjerstad, A. Spurkland Tags: Experimental Immunology Source Type: research
Issue Information ‐ TOC
(Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 1, 2017 Category: Allergy & Immunology Tags: Issue Information Source Type: research
Issue Information
(Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - March 1, 2017 Category: Allergy & Immunology Tags: Issue Information Source Type: research
