Time ‐dependent distinct roles of Toll‐like receptor 4 in a house dust mite‐induced asthma mouse model
Abstract
House dust mites (HDMs) are a common source of allergens that trigger both allergen‐specific and innate immune responses in humans. Here, we examined the effect of allergen concentration and the involvement of Toll‐like receptor 4 (TLR4) in the process of sensitization to house dust mite allergens in an HDM extract‐induced asthma mouse model. Intranasal administration of HDM extract induced an immunoglobulin E response and eosinophilic inflammation in a dose‐dependent manner from 2.5 to 30 μg/dose. In TLR4‐knockout mice, the infiltration of eosinophils and neutrophils into the lung was decreased comp...
Source: Scandinavian Journal of Immunology - February 6, 2018 Category: Allergy & Immunology Authors: T. Ishii, Y. Niikura, K. Kurata, M. Muroi, K. Tanamoto, T. Nagase, M. Sakaguchi, N. Yamashita Tags: EXPERIMENTAL IMMUNOLOGY Source Type: research
Hypoxia induces production of citrullinated proteins in human fibroblast ‐like synoviocytes through regulating HIF1α
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Ruohan Yu, Changhong Li, Lin Sun, Leilei Jian, Zhenzhen Ma, Jinxia Zhao, Xiangyuan Liu Tags: Regular Article Source Type: research
Immune activation by nucleic acids: a role in pregnancy complications
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Barbora Kone čná, Lucia Lauková, Barbora Vlková Tags: Review Source Type: research
Medawar's “Actively Acquired Tolerance” and the Danger Model: Setting the Record Straight
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Ghassan Al ‐Yassin Tags: Regular Article Source Type: research
Alternative Th17 and CD4+CD25+FoxP3+ cells frequency increase and correlate with worse cardiac function in Chagas cardiomyopathy
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Mariana S. Almeida, Virginia M.B. Lorena, Carolina de Ara újo Medeiros, Wilson Oliveira Junior, Maria da Glória A. M. Cavalcanti, Silvia M. Martins, Clarice N.L. de Morais Tags: Regular Article Source Type: research
Endothelial extracellular vesicles modulate the macrophage phenotype: Potential implications in atherosclerosis
ConclusionsIn summary, the present study provides novel insights into the pathophysiological effects of altered EV secretion and/or microRNA content and their influence on modulating monocyte activation depending on the environment surrounding EVs‐releasing ECs.This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Shaolin He, Chun Wu, Junhui Xiao, Dazhu Li, Ziyan Sun, Ming Li Tags: Regular Article Source Type: research
Interleukin ‐17A participates in podocyte injury by inducing IL‐1β secretion through ROS‐NLRP3 inflammasome‐caspase‐1 pathway
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Junli Yan, Yao Li, Haiping Yang, Li Zhang, Baohui Yang, Mo Wang, Qiu Li Tags: Regular Article Source Type: research
BLIMP ‐1 is insufficient to induce antibody secretion in the absence of IRF4 in DT40 cells
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Paulina M. Budzy ńska, Minna K. Kyläniemi, Olli Lassila, Kalle‐Pekka Nera, Jukka Alinikula Tags: Regular Manuscript Source Type: research
Clinical and Genetic Features of the Patients with X ‐Linked Agammaglobulinemia from Turkey: Single Center Experience
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Saliha Esenboga, Deniz Çagdas, Tuba T. Ozgur, Pınar Gur Çetinkaya, Lutfiye M. Turkdemir, Ozden Sanal, Mirjam VanDer Burg, İlhan Tezcan Tags: Regular Manuscript Source Type: research
Soluble MHC Class II ‐driven Therapy for a Systemic Lupus Erythematosus Murine Experimental in vitro and in vivo Model
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - February 1, 2018 Category: Allergy & Immunology Authors: Katerina Bakela, Myrsini Dimakopoulou, Panagiota Batsou, Nikos Manidakis, Irene Athanassakis Tags: Regular Article Source Type: research
T cell cross ‐reactivity may explain the large variation in how patients respond to checkpoint inhibitors
This article is protected by copyright. All rights reserved. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - January 31, 2018 Category: Allergy & Immunology Authors: Mouldy Sioud Tags: Review Source Type: research
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Scandinavian Journal of Immunology,Volume 87, Issue 3, March 2018. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - January 30, 2018 Category: Allergy & Immunology Source Type: research
MUC1 ‐ and Survivin‐based DNA Vaccine Combining Immunoadjuvants CpG and interleukin‐2 in a Bicistronic Expression Plasmid Generates Specific Immune Responses and Antitumour Effects in a Murine Colorectal Carcinoma Model
In conclusion, the DNA vaccine containing a CpG motif in bicistronic form showed good effects on colorectal cancer by inhibiting both tumour growth and metastasis, and combination with oxaliplatin could improve its antitumour effects. (Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - January 25, 2018 Category: Allergy & Immunology Authors: C. Liu, Y. Xie, B. Sun, F. Geng, F. Zhang, Q. Guo, H. Wu, B. Yu, J. Wu, X. Yu, W. Kong, H. Zhang Tags: Experimental Immunology Source Type: research
Issue Information
(Source: Scandinavian Journal of Immunology)
Source: Scandinavian Journal of Immunology - January 25, 2018 Category: Allergy & Immunology Tags: Issue Information Source Type: research
