Revista Brasileira de Farmacognosia 
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This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.Phytochemical study of Pilosocereus pachycladus and antibiotic-resistance modifying activity of syringaldehyde
ABSTRACT Pilosocereus pachycladus F. Ritter, Cactaceae, popularly known as "facheiro", is used as food and traditional medicine in Brazilian caatinga ecoregion. The plant is used to treat prostate inflammation and urinary infection. The present work reports the first secondary metabolites isolated from P. pachycladus. Therefore, the isolated compound 4-hydroxy-3,5-dimethoxy benzaldehyde (syringaldehyde) was evaluated as modulator of Staphylococcus aureus pump efflux-mediated antibiotic resistance. The isolation of compounds was performed using chromatographic techniques and the structural elucidation was carried out by spe...
Source: Revista Brasileira de Farmacognosia - September 4, 2017 Category: Drugs & Pharmacology Source Type: research
Schinus terebinthifolius: phenolic constituents and in vitro antioxidant, antiproliferative and in vivo anti-inflammatory activities
This study reports that the crude extract and isolated compounds of S. terebinthifolius (leaves) have in vitro antioxidant, antiproliferative, and in vivo anti-inflammatory activities. The samples were evaluated for antioxidant activity using 2, 2-diphenyl-1-picrylhydrazyl, β -carotene/linoleic acid and 2,2 ′ -azino-bis-(3-ethylbenzothiazoline)-6-sulphonic acid reagents. The anti-inflammatory effects were assayed against a carrageenan-induced paw oedema model in mice to test doses of 10, 100 and 300 mg/kg at different time points in addition to myeloperoxidase activity analysis. The antiproliferative activity was evalua...
Source: Revista Brasileira de Farmacognosia - September 4, 2017 Category: Drugs & Pharmacology Source Type: research
Chemical composition and antibacterial activity of essential oil from leaves of Croton heliotropiifolius in different seasons of the year
ABSTRACT This paper reports the first study of the variation of the chemical composition and abundance of the essential oil of Croton heliotropiifolius, in four seasons, and the evaluation of its antibacterial activity. Essential oil obtained from leaves of C. heliotropiifolius were analyzed by GC/MS and evaluated against eight bacteria strains by broth microdilution method. The chemical constituents identified were the same in all samples, but with different proportions. The total percentages identified were 96.58% in summer, 92.08% in autumn, 98.44% in winter and 90.78% in spring. The majors constituents are β -caryophy...
Source: Revista Brasileira de Farmacognosia - September 4, 2017 Category: Drugs & Pharmacology Source Type: research
HPLC-MS profiling of the multidrug-resistance modifying resin glycoside content of Ipomoea alba seeds
ABSTRACT High performance liquid chromatography profiling with mass spectrometry detection was applicable to identify known and novel multidrug-resistance glycolipid inhibitors from the complex resin glycosides mixture of Ipomoea alba L., Convolvulaceae, seeds. Albinosides X and XI were purified by recycling liquid chromatography and their structural elucidation was accomplished by nuclear magnetic resonance. Albinoside XI exerted a strong potentiation of vinblastine susceptibility in multidrug-resistant human breast carcinoma cells. (Source: Revista Brasileira de Farmacognosia)
Source: Revista Brasileira de Farmacognosia - September 4, 2017 Category: Drugs & Pharmacology Source Type: research
Qualitative and quantitative analysis of the phenolic content of Connarus var. angustifolius, Cecropia obtusa, Cecropia palmata and Mansoa alliacea based on HPLC-DAD and UHPLC-ESI-MS/MS
ABSTRACT The phenolic content of the medicinal species Connarus perrottetti var. angustifolius Radlk., Connaraceae, Cecropia obtuse Tr écul, Cecropia palmata Willd., Urticaceae; and Mansoa alliacea (Lam.) A.H.Gentry, Bignoniaceae, collected in three different years was evaluated. Plant infusions and hydroalcoholic, butanol and ethyl acetate extracts were analyzed by high-performance liquid chromatography with diode array detection . In order to endorse these results, analysis by electrospray mass spectrometry was also performed. Were identified: gallic acid, catechin, caffeic acid, ferulic acid, rutin, quercitrin and resv...
Source: Revista Brasileira de Farmacognosia - September 4, 2017 Category: Drugs & Pharmacology Source Type: research
Chemical composition and seasonal variation of the volatile oils from Trembleya phlogiformis leaves
ABSTRACT Trembleya phlogiformis DC., Melastomataceae, is a shrub whose leaves are used as a dye for dyeing wool and cotton. The present article aimed to carry out the morphological description of the species, to study the chemical composition of volatile oils from the leaves and flowers and the seasonal variability from the leaves during a year. Macroscopic characterization was carried out with the naked eye and with a stereoscopic microscope. Volatile oils were isolated by hydrodistillation in Clevenger apparatus and analyzed by gas chromatography/mass spectrometry. The major components of the volatile oil of T. phlogifor...
Source: Revista Brasileira de Farmacognosia - September 4, 2017 Category: Drugs & Pharmacology Source Type: research
Chemical composition of the leaf oil of Artabotrys jollyanus from Côte d’Ivoire
ABSTRACT One oil sample isolated from leaves of Artabotrys jollyanus Pierre, Annonaceae, from C ôte d ’ Ivoire has been analyzed by GC(RI), GC-MS and 13C NMR. In total, thirty-seven compounds accounting for 96.9% of the relative composition have been identified. The composition of the essential oil was dominated by trans-calamenene (15.7%), α -copaene (14.8%), α -cubebene (10.4%), cadina-3,5-diene (10.3%), (E)- β -caryophyllene (6.3%) and cadina-1,4-diene (6.1%). 13C NMR spectroscopy was very useful in the identification of trans-calamenene, 7-hydroxycalamenene, cadina-3,5-diene and cadina-1,4-diene. Moreover, monito...
Source: Revista Brasileira de Farmacognosia - September 4, 2017 Category: Drugs & Pharmacology Source Type: research
Leaf morphology and venation of Psidium species from the Brazilian Savanna
ABSTRACT The Brazilian Savanna biome has the largest plant diversity among savannas worldwide and is the predominant biome in Goi ás state, Brazil. Among plant species previously catalogued in the Brazilian Savanna, the Myrtaceae family has received attention, as these plants show great economic potential for its medicinal properties, food and ecological importance, highlighting in this context the Psidium genus. In order to contribute to the differentiation of problematic taxonomic groups, such as Myrtaceae, and to quality control of its plant material, morphological and venation leaf studies of four species of Psidium w...
Source: Revista Brasileira de Farmacognosia - September 4, 2017 Category: Drugs & Pharmacology Source Type: research
Utilization of dynamic light scattering to evaluate Pterodon emarginatus oleoresin-based nanoemulsion formation by non-heating and solvent-free method
This study opens new perspectives for bioactive evaluation of this novel nano-product. (Source: Revista Brasileira de Farmacognosia)
Source: Revista Brasileira de Farmacognosia - June 26, 2017 Category: Drugs & Pharmacology Source Type: research
Plants from the Brazilian Traditional Medicine: species from the books of the Polish physician Piotr Czerniewicz (Pedro Luiz Napoleão Chernoviz, 1812–1881)
Abstract The Brazilian flora is very rich in medicinal plants, and much information about the traditional use of the Brazilian plants is only available from early literature and we are facing a rapid process of loss of biodiversity. To retrieve data about useful plants registered in the books of the Polish physicist P.L.N. Chernoviz, who lived in Brazil for 15 years in the 19th century. The aim is to improve our knowledge about Brazilian plants, and to ensure the benefits of sharing it with potential users. Data about Brazilian plants were obtained from six editions of the book Formulary and Medical Guide (Formul ário e G...
Source: Revista Brasileira de Farmacognosia - June 26, 2017 Category: Drugs & Pharmacology Source Type: research
Ecuadorian honey types described by Kichwa community in Rio Chico, Pastaza province, Ecuador using Free-Choice Profiling
In this study sensory characteristics of Ecuadorian false and genuine honeys with diverse entomological origin: Apis mellifera – light amber and amber, Geotrigona leucogastra, Melipona grandis and Scaptotrigona sp. (S. ederi np Schwarz) were investigated with Kichwa assessors (four female and four male, aged 18 – 62 years old). The panel was asked to taste and to identify sensory attributes of honey (appearance, taste, smell, aroma, mouthfeel, other tactile sensations), and to score their intensities in 10 cm unstructured line scales anchored with the words weak and strong, using the Free-Choice Profile methodology Th...
Source: Revista Brasileira de Farmacognosia - June 26, 2017 Category: Drugs & Pharmacology Source Type: research
Pterodon pubescens oil nanoemulsions: physiochemical and microbiological characterization and in vivo anti-inflammatory efficacy studies
Abstract Pterodon pubescens (Benth.) Benth., Fabaceae, fruits have been investigated for their anti-inflammatory and antinociceptive activities, and have demonstrated effectiveness in inflammatory conditions. A physiochemical and microbiological stability study was conducted to investigate two nanoemulsion-based delivery systems of two different hydrophilic surfactants (polyethylene glycol-40H castor oil or polyethylene glycol-40 castor oil). The nanoemulsions, containing P. pubescens oil, lecithin, hydrophilic surfactant and water, were analyzed for droplet size distribution, polydispersity index, pH, consistency index, s...
Source: Revista Brasileira de Farmacognosia - June 26, 2017 Category: Drugs & Pharmacology Source Type: research
Anti-inflammatory activity and chemical composition of dichloromethane extract from Piper nigrum and P. longum on permanent focal cerebral ischemia injury in rats
Abstract White pepper (Piper nigrum L.) and long pepper (Piper longum L.) belong to family Piperaceae and are commonly used as household spices and traditional medicine worldwide, specifically in China and Southeast Asia. In Traditional Chinese Hui Medicine, these herbs are widely used for treatment of stroke. Our present study investigated effects of these herbs on inflammation in rat model with cerebral ischemia. After subjecting the rats to permanent middle cerebral artery occlusion (pMCAO) for 6 h, at doses of 100 and 200 mg/kg, dichloromethane fraction from white pepper and long pepper, respectively, was intragastrica...
Source: Revista Brasileira de Farmacognosia - June 26, 2017 Category: Drugs & Pharmacology Source Type: research
Rats treated with Hypericum perforatum during pregnancy generate offspring with behavioral changes in adulthood
Abstract Drugs used in the treatment of depression can cross the placenta giving rise to questions regarding the effects these drugs exert on the fetus. Hypericum perforatum L., Hypericaceae, is a natural product used to treat depression. However, information about its toxicity and the occurrence of alterations in the central nervous system development of the offspring is scarce. This work assessed the behavior of adult male rats born from mothers treated with Hypericum extract during gestation and analyzed the fluorescence of the extract in different organs of mothers and fetuses. Male pups were divided into three treated...
Source: Revista Brasileira de Farmacognosia - June 26, 2017 Category: Drugs & Pharmacology Source Type: research
Reproductive effects of the psychoactive beverage ayahuasca in male Wistar rats after chronic exposure
This study aimed to investigate the reproductive effects of this beverage in male Wistar rats after chronic exposure. The rats were treated by gavage every other day for 70 days at 0 (control), 1 ×, 2×, 4× and 8× the dose used in a religious ritual (12 animals per group), and animals euthanized on the 71st day. Compared to controls, there was a significant decrease in food consumption and body weight gain in rats from the 4× and 8× groups, and a significant increase in the brain and st omach relative weight at the 8× group. There was a significant increase in total serum testosterone, and a decrease in spermatic tra...
Source: Revista Brasileira de Farmacognosia - June 26, 2017 Category: Drugs & Pharmacology Source Type: research
