Recent trends in the treatment of unresectable stage III non-small-cell lung cancer
Publication date: Available online 15 April 2019Source: Respiratory InvestigationAuthor(s): Go Makimoto, Katsuyuki Hotta, Katsuyuki KiuraAbstractApproximately 20–25% of non-small-cell lung cancer (NSCLC) is diagnosed when the disease has progressed to clinical stage III. At this stage, and even if the cancer is considered unresectable, the treatment strategy should aim to achieve a cure. At the time of the initial diagnosis, it is necessary for medical oncologists to devise the best treatment strategy for each patient by composing a multidisciplinary treatment team including thoracic surgeons and radiation oncologists. I...
Source: Respiratory Investigation - April 16, 2019 Category: Respiratory Medicine Source Type: research
Microdeletion in Xq28 with a polymorphic inversion in a patient with FLNA-associated progressive lung disease
We report the first Japanese case of FLNA-associated progressive lung disease caused by a microdeletion in Xq28 encompassing the FLNA gene with a polymorphic inversion. (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 14, 2019 Category: Respiratory Medicine Source Type: research
Criteria for the diagnosis of idiopathic pleuroparenchymal fibroelastosis: A proposal
ConclusionsWe have proposed diagnostic criteria for IPPFE in patients with and without SLB. Both imaging criteria and physiological criteria using RV/TLC and BMI successfully discriminate IPPFE from chronic IIPs when SLB cannot be performed. (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 11, 2019 Category: Respiratory Medicine Source Type: research
Our obligation to find treatable and untreatable traits in patients with chronic airway diseases
Publication date: Available online 6 April 2019Source: Respiratory InvestigationAuthor(s): Hisako Matsumoto (Source: Respiratory Investigation)
Source: Respiratory Investigation - April 6, 2019 Category: Respiratory Medicine Source Type: research
A difference in the effects of a comorbidity of allergic rhinitis on asthma symptoms between obese and non-obese patients
Publication date: Available online 27 March 2019Source: Respiratory InvestigationAuthor(s): Masako To, Ryuta Tsuzuki, Otohiro Katsube, Satoshi Yamawaki, Seiko Soeda, Yuta Kono, Natsue Honda, Ichino Kano, Kosuke Haruki, Yasuo To (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 28, 2019 Category: Respiratory Medicine Source Type: research
Meteorological effects on severe hemoptysis: A hospital-based observational study
ConclusionsLower relative humidity was a significant risk factor for the development of hemoptysis. Clinicians should be aware of the potential for increases in hemoptysis events on days with low ambient humidity. (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 21, 2019 Category: Respiratory Medicine Source Type: research
Treatment outcome of patients with unresectable stage III non-small cell lung cancer and interstitial pneumonia
ConclusionsCRT was the only predictive factor for longer survival in LC patients; however, no LC-IP patients received CRT, possibly because of the underlying IP. (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 19, 2019 Category: Respiratory Medicine Source Type: research
Evaluation and management of Idiopathic Pulmonary Fibrosis
Publication date: Available online 8 March 2019Source: Respiratory InvestigationAuthor(s): Tomoo KishabaAbstractIdiopathic Pulmonary Fibrosis (IPF) is a most common progressive interstitial lung disease (ILD) of unknown etiology, although majority of patients are elderly male smokers. The main pathogenesis is aberrant recovery of epithelial injury and collagen deposition. Fibrotic nonspecific interstitial pneumonia, connective tissue disease (CTD) especially rheumatoid arthritis (RA) associated ILD, and chronic hypersensitivity pneumonia(CHP) are important differential diagnosis. Main symptoms are non-productive cough and ...
Source: Respiratory Investigation - March 8, 2019 Category: Respiratory Medicine Source Type: research
Editorial Board
Publication date: March 2019Source: Respiratory Investigation, Volume 57, Issue 2Author(s): (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 7, 2019 Category: Respiratory Medicine Source Type: research
Appreciation to Reviewers
Publication date: March 2019Source: Respiratory Investigation, Volume 57, Issue 2Author(s): (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 7, 2019 Category: Respiratory Medicine Source Type: research
Asthma mortality based on death certificates: A demographic survey in Kagawa, Japan
ConclusionRe-examination of the death certificate revealed that asthma deaths were reported incorrectly on the death certificates of elderly patients who died outside the hospital. (Source: Respiratory Investigation)
Source: Respiratory Investigation - March 4, 2019 Category: Respiratory Medicine Source Type: research
Prevalence of sleep disturbances: Sleep disordered breathing, short sleep duration, and non-restorative sleep
Publication date: Available online 1 March 2019Source: Respiratory InvestigationAuthor(s): Takeshi Matsumoto, Kazuo ChinAbstractRecently, interest in sleep disturbances, such as sleep disordered breathing (SDB), short sleep duration, and non-restorative sleep (NRS), has been increasing. The potentially large public health implications of sleep disturbances indicate a need to determine their prevalence in a general population. This review describes the characteristics of population-based sleep cohorts from past to present. Unavoidable methodological and baseline characteristic heterogeneity was found between studies. The pr...
Source: Respiratory Investigation - March 1, 2019 Category: Respiratory Medicine Source Type: research
Pneumocystis pneumonia in HIV-1-infected patients
Publication date: Available online 26 February 2019Source: Respiratory InvestigationAuthor(s): Satoshi Shibata, Toshiaki KikuchiAbstractPneumocystis pneumonia (PCP) is an opportunistic disease that mainly affects patients with a deficiency of cell-mediated immunity, especially acquired immunodeficiency syndrome (AIDS). The incidence of PCP in these patients has declined substantially owing to the widespread use of antiretroviral therapy and PCP prophylaxis. However, PCP is still a major AIDS-related opportunistic infection, particularly in patients with advanced immunosuppression in whom human immunodeficiency virus type 1...
Source: Respiratory Investigation - February 27, 2019 Category: Respiratory Medicine Source Type: research
Serial KL-6 analysis in patients with idiopathic pulmonary fibrosis treated with nintedanib
Publication date: Available online 21 February 2019Source: Respiratory InvestigationAuthor(s): Laura Bergantini, Elena Bargagli, Paolo Cameli, Behar Cekorja, Nicola Lanzarone, Lucrezia Pianigiani, Lucia Vietri, David Bennett, Piersante Sestini, Paola Rottoli (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 22, 2019 Category: Respiratory Medicine Source Type: research
Ten-year experience of smoking cessation in a single center in Japan
ConclusionsBaseline exhaled CO level and mental disorders were significantly associated with either success or failure of smoking cessation. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 20, 2019 Category: Respiratory Medicine Source Type: research
