Mysterious link between the restrictive ventilatory impairment in spirometry and cardiovascular disease
Publication date: Available online 15 February 2019Source: Respiratory InvestigationAuthor(s): Yoko Shibata (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 16, 2019 Category: Respiratory Medicine Source Type: research
Impact of reduced pulmonary function in the Japanese general population: Lessons from the Yamagata-Takahata study
Publication date: Available online 14 February 2019Source: Respiratory InvestigationAuthor(s): Yoko Shibata, Sumito Inoue, Masafumi WatanabeAbstractRegional epidemiological studies for respiratory diseases have been rarely performed in Japan, because spirometry is not regularly conducted in the standard annual health checks. The Yamagata-Takahata Study is an epidemiological study utilizing regional characteristics based on the 21st Century Centers of Excellence (COE) Program and the Global COE Program. Spirometric examination and other specific measurements via blood sampling were performed for the study participants in an...
Source: Respiratory Investigation - February 15, 2019 Category: Respiratory Medicine Source Type: research
Low starting-dosage of nintedanib for the reduction of early termination
Publication date: Available online 13 February 2019Source: Respiratory InvestigationAuthor(s): Satoshi Ikeda, Akimasa Sekine, Tomohisa Baba, Takuma Katano, Erina Tabata, Ryota Shintani, Hideaki Yamakawa, Takashi Niwa, Tsuneyuki Oda, Ryo Okuda, Hideya Kitamura, Takashi Ogura (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 14, 2019 Category: Respiratory Medicine Source Type: research
Respiratory resistance among adults in a population-based cohort study in Northern Japan
ConclusionThe present distribution values and their relation to clinical and biological data should provide useful insights for clinical settings and serve as a helpful guide in implementing FOT.Forced oscillation technique, respiratory system resistance, respiratory system reactance, gender difference, obesity. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 13, 2019 Category: Respiratory Medicine Source Type: research
Obesity is strongly and independently associated with a higher prevalence of pulmonary embolism
ConclusionObesity has been consistently associated with pulmonary embolism over the years studied using a large inpatient database. This association has been persistent over a period of 10 years and is consistent with the negative effects of obesity on the cardiopulmonary system. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 13, 2019 Category: Respiratory Medicine Source Type: research
Management and utility of transbronchial lung cryobiopsy in Japan
ConclusionsThis is the first report from Japan analyzing the efficacy and feasibility of TBLC in daily clinical practice. TBLC was considered efficacious, safe, and feasible for Japanese patients with various lung diseases. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 11, 2019 Category: Respiratory Medicine Source Type: research
Coexistence of dementia with smear-positive pulmonary tuberculosis is associated with patient in-hospital mortality
ConclusionsThe comorbidity of dementia with pulmonary TB was associated with patient in-hospital mortality. Medical practitioners should be aware of dementia in patients with smear-positive pulmonary TB to identify high-mortality groups. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 11, 2019 Category: Respiratory Medicine Source Type: research
Current status of diagnostic and therapeutic bronchoscopy in Japan: 2016 national survey of bronchoscopy
ConclusionsThrough this survey, the advanced safety of bronchoscopic examination has been secured in many facilities. A continuous monitoring of bronchoscopic practices with respect to safety management is recommended. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 7, 2019 Category: Respiratory Medicine Source Type: research
Improved cough- and sputum-related quality of life after initiation of treatment in pulmonary tuberculosis
ConclusionsCough- and sputum-related QOL was impaired in patients with pulmonary TB before treatment but improved after initiation of treatment regardless of the clinical characteristics. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 7, 2019 Category: Respiratory Medicine Source Type: research
Safety, efficacy, and pharmacokinetics of bedaquiline in Japanese patients with pulmonary multidrug-resistant tuberculosis: An interim analysis of an open-label, phase 2 study
ConclusionsNo new safety signals in patients, including those receiving bedaquiline with BR beyond 24 weeks, and the faster culture conversion time indicate that the administration of bedaquiline as part of a multi-drug regimen for at least 24 weeks is a suitable treatment for adult Japanese patients with pMDR-TB. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 7, 2019 Category: Respiratory Medicine Source Type: research
Radiological patterns of pulmonary involvement may predict treatment response in rheumatoid arthritis: A retrospective study
ConclusionsThese results suggest that NSIP and bronchiolitis HRCT patterns may be risk factors for resistance to RA therapy. (Source: Respiratory Investigation)
Source: Respiratory Investigation - February 2, 2019 Category: Respiratory Medicine Source Type: research
Exacerbation of chronic pulmonary aspergillosis was associated with a high rebleeding rate after bronchial artery embolization
ConclusionsBronchial artery embolization was effective in controlling hemoptysis in patients with CPA, especially those who could not undergo surgical resection. However, disease control of CPA was important to prevent rebleeding over the long term and to improve survival after BAE. (Source: Respiratory Investigation)
Source: Respiratory Investigation - January 26, 2019 Category: Respiratory Medicine Source Type: research
Editorial Board
Publication date: January 2019Source: Respiratory Investigation, Volume 57, Issue 1Author(s): (Source: Respiratory Investigation)
Source: Respiratory Investigation - January 15, 2019 Category: Respiratory Medicine Source Type: research
A mini systematic review of prognostic factors in elderly patients with tuberculosis
ConclusionsThe prognostic factors of tuberculosis in elderly patients varied according to the income levels of the countries. The factors in Taiwan and Japan were mainly associated with host factors, irrespective of the cause of death, which may reflect senile deterioration due to old age. (Source: Respiratory Investigation)
Source: Respiratory Investigation - January 11, 2019 Category: Respiratory Medicine Source Type: research
Germline mutations in lung cancer
Publication date: Available online 11 January 2019Source: Respiratory InvestigationAuthor(s): Takehito Shukuya, Kazuhisa TakahashiAbstractGenetic testing for alterations in oncogenic driver genes has become essential and standard in the clinical practice of the treatment of lung cancer. Germline mutations potentially predisposing patients to lung cancer are rare; however, with the introduction of next-generation sequencing in the clinical practice of lung cancer, the identification of potentially predisposing germline abnormalities is becoming more common. In addition, liquid biopsy, which analyzes cell-free DNA in blood, ...
Source: Respiratory Investigation - January 11, 2019 Category: Respiratory Medicine Source Type: research
