Choreoathetosis: a result of uncontrolled diabetes
(Source: Practical Diabetes International)
Source: Practical Diabetes International - September 8, 2014 Category: Endocrinology Authors: Nadia Zarif, Andrea Norris Tags: Diabetes vignette Source Type: research

Profound weight reduction with GLP‐1 agonist therapy: a delayed hyper‐response
(Source: Practical Diabetes International)
Source: Practical Diabetes International - September 8, 2014 Category: Endocrinology Authors: Andrew P McGovern, Neil Munro, Kenneth Watters, Michael Feher Tags: Diabetes vignette Source Type: research

Review of clinical use of glucagon‐like peptide‐1 in the management of type 2 diabetes
This study confirms GLP‐1 agents provide clinically useful reductions in HbA1c and weight. Further work is required to assess their effect if used earlier. A practical and pragmatic approach to assessment of the effectiveness of GLP‐1 has been proposed. Copyright © 2014 John Wiley & Sons, Ltd. (Source: Practical Diabetes International)
Source: Practical Diabetes International - September 8, 2014 Category: Endocrinology Authors: Gordon F Rushworth, Jennifer Connelly, Wendy Laing, Benjamin H Maskrey, Fiona Nicholas, Sandra M MacRury Tags: Original Article Source Type: research

Prevalence of metabolic risk factors and associated 10‐year prediction of cardiovascular disease and diabetes in female employees
This study examined the prevalence of undiagnosed risk factors associated with these two conditions and predicted 10‐year risk. Female local health board employees (n = 371) with no prior diagnosis of CVD or T2DM accepted an invitation for a workplace‐based health assessment. Demographic, anthropometric, systolic and diastolic blood pressure, family and medical histories were all recorded and capillary blood samples obtained for analysis of total and HDL cholesterol and HbA1c. Ten‐year CVD and T2DM risk were predicted using the QRISK2 and QDiabetes algorithms, respectively. A significant proportion of females were ei...
Source: Practical Diabetes International - September 8, 2014 Category: Endocrinology Authors: Benjamin J Gray, Richard M Bracken, Daniel Turner, Kerry Morgan, Stephen D Mellalieu, Michael Thomas, Sally P Williams, Meurig Williams, Sam Rice, Jeffrey W Stephens, Tags: Original Article Source Type: research

New technologies and drugs in the management of diabetic retinopathy
Abstract Diabetic retinopathy remains one of the most common and most feared causes of blindness and visual impairment in adults of working age despite the availability of effective treatment for more than 30 years. Sight‐threatening diabetic retinopathy consists of two distinct clinical entities: proliferative diabetic retinopathy (PDR) and diabetic macular oedema (DMO or maculopathy) which may coexist, both of which can be detected by clinical or photographic screening before vision is affected, thereby allowing treatment to be offered before visual impairment has developed. Laser photocoagulation has been the mainstay...
Source: Practical Diabetes International - September 8, 2014 Category: Endocrinology Authors: Hamish MA Towler Tags: Review Source Type: research

Psychosocial risk screening for children and adolescents at diabetes onset
(Source: Practical Diabetes International)
Source: Practical Diabetes International - September 8, 2014 Category: Endocrinology Authors: Anna Lindholm Olinder, Janeth Leksell Tags: Leader Source Type: research

Taste and smell in diabetes
(Source: Practical Diabetes International)
Source: Practical Diabetes International - September 1, 2014 Category: Endocrinology Authors: Rowan Hillson Tags: Leader Source Type: research

Apixaban
(Source: Practical Diabetes International)
Source: Practical Diabetes International - August 12, 2014 Category: Endocrinology Authors: Rachel Livingstone, Miles Fisher, Gerry McKay Tags: Drug notes Source Type: research

The National Paediatric Diabetes Audit
(Source: Practical Diabetes International)
Source: Practical Diabetes International - August 12, 2014 Category: Endocrinology Authors: Justin Warner, Siôn Morris Tags: Short Report Source Type: research

Using motivational interviewing to engage adolescents and young adults with diabetes
Abstract For young people trying to keep diabetes under control the behaviours can appear simple; e.g. following a healthy diet, regular self‐monitoring and exercise. However, clinicians and parents are often frustrated by the gap between the ‘ideal’ and ‘reality’. Young people have conflicting motivations and pressures; a change in behaviour feels too big, the rewards too distant, the personal or financial costs too high, or maybe it was never their idea to change in the first place. Attention has turned to the potential of motivational interviewing in the paediatric setting, particularly with the adolescent age...
Source: Practical Diabetes International - August 12, 2014 Category: Endocrinology Authors: Deborah Christie, Sue Channon Tags: Practice point Source Type: research

Diabetes in the young: technology, engagement and context
Abstract Over the last three decades, while insulin replacement in type 1 diabetes in the young remains fundamental, the methods of delivering this therapy have changed dramatically. ‘Intensive insulin’ therapy offers the best outcome, in terms of glycaemia and long‐term health, and a shift to multiple injection therapy and pumps has become the approach promoted early after diagnosis. A recent recognition is the sustained effect of near‐normal glycaemia from diagnosis (‘metabolic memory’), achieved through strict glucose targets and dose adjustment of insulin for carbohydrate. To use the developing technology o...
Source: Practical Diabetes International - August 12, 2014 Category: Endocrinology Authors: Stephen Greene Tags: State of the art lecture Source Type: research

Transitional care for young people with diabetes: a national registry is urgently needed
Abstract Young people with diabetes require specialised and personalised care as they make the transition from children's services to adult services. Getting the right care at this stage of their lives gives them the best chance of avoiding longer‐term complications and remaining within the health service. Many policy documents and guidelines have been issued highlighting the importance of diabetes care during these years but little evidence exists as to what should constitute that care and how it should be provided. Few interventions have been evaluated and there are no national data comparing the effectiveness of trans...
Source: Practical Diabetes International - August 12, 2014 Category: Endocrinology Authors: Rustam Rea Tags: Review Source Type: research

Children and youth with type 1 diabetes developing concomitant autoimmune disease do not exhibit worsening metabolic control or growth impairment
This study aimed to evaluate the effect of type 1 diabetes mellitus (T1DM) and concurrent autoimmune condition (AI) on glycaemic control and growth in children. Twenty‐eight children with T1DM and associated autoimmune condition were matched by sex and age at onset with two controls each. HbA1c, height standard deviation scores (SDS), weight SDS and BMI SDS were measured between six months and five years after developing T1DM. We included 28 children with T1DM and AI (10 males) and 56 (20 males) age and sex matched controls with T1DM. Out of the 28 patients with AI conditions, 21 (75%) had coeliac disease (CD), eight (28...
Source: Practical Diabetes International - August 12, 2014 Category: Endocrinology Authors: Astha Soni, Emily Jayne Shaw, Anuja Natarajan, Sze May Ng Tags: Original Article Source Type: research

Physical activity and sedentary behaviour in Scottish youth with type 1 diabetes
Abstract The purpose of this study was to objectively measure physical activity and sedentary behaviour, across week and weekend days, in Scottish children and adolescents with type 1 diabetes mellitus. Forty patients aged 7–9 years (n = 20) or 12–14 years (n = 20) wore accelerometers for seven days. Validated cut‐points categorised sedentary behaviour, <100cpm, and moderate to vigorous physical activity (MVPA), ≥3200cpm. Differences in behaviour based on age, gender, and diabetes treatment therapy, and patterns in behaviour were explored. The average sedentary time was 10.2 ± 1.7 hours/day and MVPA...
Source: Practical Diabetes International - August 12, 2014 Category: Endocrinology Authors: Freya MacMillan, Alison Kirk, Nanette Mutrie, Kenneth Robertson Tags: Original Article Source Type: research

The role of sedentary behaviour in type 1 diabetes
F MacMillan, et al. Physical activity and sedentary behaviour in Scottish youth with type 1 diabetes. Pages 228–233. (Source: Practical Diabetes International)
Source: Practical Diabetes International - August 12, 2014 Category: Endocrinology Authors: Emma Wilmot Tags: Commentary Source Type: research