Improving periodontal outcomes: merging clinical and behavioral science
Abstract New data indicate that periodontal diseases are much more prevalent than previously thought, which means that there are large numbers of patients who will need to be diagnosed and treated for periodontal disease in a general dental practice. Oral hygiene procedures performed by patients between office visits are important for gingival health. No particular type of toothbrush has consistently been shown to have superior plaque‐removal ability over another. Although studies on powered brushes have shown evidence for efficacy of biofilm removal and increased patient compliance, they are of short duration, making ev...
Source: Periodontology 2000 - April 3, 2016 Category: Dentistry Authors: Rebecca S. Wilder, Kimberly S. Bray Tags: Review Article Source Type: research

The tobacco‐using periodontal patient: role of the dental practitioner in tobacco cessation and periodontal disease management
Abstract Although the prevalence of tobacco use has declined in some parts of the world, tobacco use remains a persistent and, in some cases, growing problem that will continue to be a fundamental challenge facing dental practitioners in the decades ahead. Dental practitioners have a unique opportunity and professional obligation to be a positive influence in reducing the economic and social burden inflicted by tobacco use on dental and general health. In this article, the current noninvasive, evidence‐based approaches are presented for dental practitioners to help patients avoid initiating tobacco use, to encourage and ...
Source: Periodontology 2000 - April 3, 2016 Category: Dentistry Authors: Benjamin W. Chaffee, Elizabeth T. Couch, Mark I. Ryder Tags: Review Article Source Type: research

Risk factors that may modify the innate and adaptive immune responses in periodontal diseases
Abstract Plaque‐induced periodontal diseases occur in response to the accumulation of dental plaque. Disease manifestation and progression is determined by the nature of the immune response to the bacterial complexes in plaque. In general, predisposing factors for these periodontal diseases can be defined as those factors which retain or hinder the removal of plaque and, depending upon the nature of the immune response to this plaque, the disease will either remain stable and not progress or it may progress and result in chronic periodontitis. In contrast, modifying factors can be defined as those factors that alter the ...
Source: Periodontology 2000 - April 3, 2016 Category: Dentistry Authors: Ellie T. Knight, Jenny Liu, Gregory J. Seymour, Clovis M. Faggion, Mary P. Cullinan Tags: Review Article Source Type: research

Risk assessment and periodontal prevention in primary care
Abstract The role of risk factors and risk assessment in the prediction of clinical periodontal outcomes, and thus in patient management, continues to be a subject of high professional interest and clinical relevance globally. Advances in our understanding of periodontal disease causality and the role of risk factors as predictors of future disease risk have led to the development of various quantitative tools to calculate risk and inform clinical decision‐making. We review the conceptual basis for periodontal risk calculation and frame its potential, as well as its limitations, in the context of similar advances in medi...
Source: Periodontology 2000 - April 3, 2016 Category: Dentistry Authors: Raul I. Garcia, Robert Compton, Thomas Dietrich Tags: Review Article Source Type: research

Minimally invasive periodontal therapy for general practitioners
Abstract There remains a high prevalence of mild‐to‐moderate forms of periodontal diseases in both developed and developing countries. Although many periodontal specialty practices currently place strong emphasis on implant surgery, periodontal plastic surgery and esthetics, general dentists and hygienists have often assumed more responsibility than periodontal specialty practices for the diagnosis, treatment, assessment and maintenance, and possible referral, of their patients. To address these current trends and challenges, this volume of Periodontology 2000 presents a series of topics on the basic biological princip...
Source: Periodontology 2000 - April 3, 2016 Category: Dentistry Authors: Mark I. Ryder, Gary C. Armitage Tags: Review Article Source Type: research

Issue information ‐ Contributors List
(Source: Periodontology 2000)
Source: Periodontology 2000 - April 3, 2016 Category: Dentistry Tags: Issue Information Source Type: research

Issue information ‐ TOC
(Source: Periodontology 2000)
Source: Periodontology 2000 - April 3, 2016 Category: Dentistry Tags: Issue Information Source Type: research

Issue information ‐ Contributors
(Source: Periodontology 2000)
Source: Periodontology 2000 - February 16, 2016 Category: Dentistry Tags: Issue Information Source Type: research

Issue information ‐ TOC
(Source: Periodontology 2000)
Source: Periodontology 2000 - February 16, 2016 Category: Dentistry Tags: Issue Information Source Type: research

Issue information ‐ Title Page
(Source: Periodontology 2000)
Source: Periodontology 2000 - February 1, 2016 Category: Dentistry Tags: Issue Information Source Type: research

Gingival crevicular fluid and saliva
Abstract Understanding the structure and function of the mouth, its tissues and secretions is of great interest to physiologists, cell biologists, immunologists and microbiologists but is also of fundamental interest to the dental professional interested in comprehending the aberrant processes associated with oral disease and in the application of effective clinical interventions. The field of periodontology, which has a truly multidisciplinary perspective cutting across leading edge molecular and cellular biology, clinical dentistry, epidemiology and behavioural science, exemplifies this. A paradigm shift in recent years ...
Source: Periodontology 2000 - December 11, 2015 Category: Dentistry Authors: John J. Taylor, Philip M. Preshaw Tags: Review Article Source Type: research

Analysis of matrix metalloproteinases, especially MMP‐8, in gingival crevicular fluid, mouthrinse and saliva for monitoring periodontal diseases
Abstract Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of‐care diagnostics to predict, diagnose and determine the progressive phases of episodic periodontitis and peri‐implantitis, as well as to monitor the treatments and medications. Matrix metalloproteinase‐8 can be used alone or together with interleukin‐1beta and Porphyromonas gingivalis to calculate cumulative risk score at the subject level as a successful diagnostic tool, especially in large‐scale public health surveys,...
Source: Periodontology 2000 - December 10, 2015 Category: Dentistry Authors: Timo Sorsa, Ulvi K. Gursoy, Solomon Nwhator, Marcela Hernandez, Taina Tervahartiala, Jussi Leppilahti, Mervi Gursoy, Eija Könönen, Gulnur Emingil, Pirkko J. Pussinen, Päivi Mäntylä Tags: Review Article Source Type: research

Saliva in studies of epidemiology of human disease: the UK Biobank project
Abstract There has been immense interest in the uses of saliva in the diagnosis of systemic disease over the past decade and longer because it is recognized that saliva possesses great potential as a diagnostic fluid. In spite of this, the usefulness of saliva in studies of the epidemiology of human disease has still to be properly evaluated. This review describes the UK Biobank project and explores the scope to use this and other such cohort studies to gain important insights into the epidemiological aspects of systemic disease. The Biobank holds around 85,000 well‐characterized saliva samples, together with blood and u...
Source: Periodontology 2000 - December 10, 2015 Category: Dentistry Authors: John W. Galloway, Bart J. F. Keijser, David M. Williams Tags: Review Article Source Type: research

Salivary cytokines as biomarkers of periodontal diseases
Abstract Research into biomarkers of periodontitis is driven by mainly three targets: to identify ‘at risk’ patients before periodontal tissue destruction occurs; to determine disease activity and progression; and to build up our understanding of this complex disease with the purpose of finding new therapeutic targets. Whilst blood and gingival crevicular fluid were previously the biological samples of choice, saliva has recently gained more attention as a readily accessible oral fluid which has a mediator profile similar to that of serum and gingival crevicular fluid. The aim of this paper was to give a comprehensive ...
Source: Periodontology 2000 - December 10, 2015 Category: Dentistry Authors: Katrin M. Jaedicke, Philip M. Preshaw, John J. Taylor Tags: Review Article Source Type: research

Analysis of matrix metalloproteinases, especially MMP‐8, in gingival creviclular fluid, mouthrinse and saliva for monitoring periodontal diseases
Abstract Matrix metalloproteinase‐8 is a promising candidate biomarker for oral fluid (gingival crevicular fluid, peri‐implant sulcular fluid and saliva) and mouthrinse chair‐side/point‐of‐care diagnostics to predict, diagnose and determine the progressive phases of episodic periodontitis and peri‐implantitis, as well as to monitor the treatments and medications. Matrix metalloproteinase‐8 can be used alone or together with interleukin‐1beta and Porphyromonas gingivalis to calculate cumulative risk score at the subject level as a successful diagnostic tool, especially in large‐scale public health surveys,...
Source: Periodontology 2000 - December 10, 2015 Category: Dentistry Authors: Timo Sorsa, Ulvi K. Gursoy, Solomon Nwhator, Marcela Hernandez, Taina Tervahartiala, Jussi Leppilahti, Mervi Gursoy, Eija Könönen, Gulnur Emingil, Pirkko J. Pussinen, Päivi Mäntylä Tags: Review Article Source Type: research