Gingival crevicular fluid and its immune mediators in the proteomic era
Abstract
The discovery of biomarkers for periodontal disease requires an in‐depth understanding of the molecular basis of the initiation and progression of the disease. The gingival crevicular fluid is a biological medium suitable for identifying and measuring such biomarkers because it can be easily and noninvasively sampled from the immediate vicinity of the affected tissues. An ever‐expanding pool of gingival crevicular fluid proteins associated with periodontal health or disease has been catalogued over the years, particularly with the recent implementation of proteomic technologies. ‘Proteomics’ refers to the ...
Source: Periodontology 2000 - November 30, 2017 Category: Dentistry Authors: Nagihan Bostanci, Georgios N. Belibasakis Tags: Review Article Source Type: research
The periodontal pocket: pathogenesis, histopathology and consequences
Abstract
The conversion of junctional epithelium to pocket epithelium is regarded as a hallmark in the development of periodontitis. Knowledge of factors contributing to the initiation and progression of pocket formation is important and may result in the development of better preventive measures and improve healing outcomes after therapeutic interventions. The periodontal pocket is a pathologically deepened gingival sulcus. In healthy periodontal conditions, the defense mechanisms are generally sufficient to control the constant microbiological challenge through a normally functioning junctional epithelium and the concent...
Source: Periodontology 2000 - November 30, 2017 Category: Dentistry Authors: Dieter D. Bosshardt Tags: Review Article Source Type: research
Treatment of pathologic peri ‐implant pockets
Periodontology 2000,Volume 76, Issue 1, Page 180-190, February 2018. (Source: Periodontology 2000)
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Source Type: research
Host modulation therapy with anti ‐inflammatory agents
Periodontology 2000,Volume 76, Issue 1, Page 131-149, February 2018. (Source: Periodontology 2000)
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Source Type: research
Molecular basis for immunohistochemical and inflammatory changes during progression of gingivitis to periodontitis
Periodontology 2000,Volume 76, Issue 1, Page 51-67, February 2018. (Source: Periodontology 2000)
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Source Type: research
Surgical treatment of the residual periodontal pocket
Periodontology 2000,Volume 76, Issue 1, Page 150-163, February 2018. (Source: Periodontology 2000)
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Source Type: research
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Periodontology 2000,Volume 76, Issue 1, Page 180-190, February 2018. (Source: Periodontology 2000)
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Source Type: research
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Periodontology 2000,Volume 76, Issue 1, Page 131-149, February 2018. (Source: Periodontology 2000)
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Source Type: research
---
Periodontology 2000,Volume 76, Issue 1, Page 51-67, February 2018. (Source: Periodontology 2000)
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Source Type: research
---
Periodontology 2000,Volume 76, Issue 1, Page 150-163, February 2018. (Source: Periodontology 2000)
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Source Type: research
Molecular basis for immunohistochemical and inflammatory changes during progression of gingivitis to periodontitis
Abstract
Two common diseases – gingivitis and periodontitis – affect the periodontium. Symptoms of disease entities are used for distinguishing various forms of gingivitis and periodontitis. Gingivitis follows a linear and progressive course when a healthy individual stops oral care, as shown by the experimental gingivitis model. It is not known if and when gingivitis transforms into periodontitis. A very limited number of studies present direct evidence regarding the histological changes over time and how they correlate to the clinical transition from gingivitis to periodontitis. This review focuses on the pathologica...
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Authors: Sivge Kurgan, Alpdogan Kantarci Tags: Original Article Source Type: research
Treatment of pathologic peri ‐implant pockets
Abstract
Peri‐implant and periodontal pockets share a number of anatomical features but also have distinct differences. These differences make peri‐implant pockets more susceptible to trauma and infection than periodontal pockets. Inadequate maintenance can lead to infections (defined as peri‐implant mucositis and peri‐implantitis) within peri‐implant pockets. These infections are recognized as inflammatory diseases, which ultimately lead to the loss of supporting bone. Diagnostic and treatment methods conventionally used in periodontics have been adopted to assess and treat these diseases. Controlling infection ...
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Authors: Stefan Renvert, Ioannis Polyzois Tags: Review Article Source Type: research
Surgical treatment of the residual periodontal pocket
Abstract
The ultimate goal of periodontal therapy is to prevent further disease progression in order to reduce the risk of tooth loss. This objective can be achieved through a number of therapeutic modalities comprising both the nonsurgical and surgical phases of periodontal therapy. Nonsurgical periodontal treatment has been shown to control periodontal infection and to arrest progression of the disease in a significant number of cases. However, despite completion of nonsurgical treatment, a number of periodontal pockets, defined as ‘residual’, often remain. The presence of residual pockets may jeopardize tooth surviv...
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Authors: Filippo Graziani, Dimitra Karapetsa, Nikolaos Mardas, Natalie Leow, Nikolaos Donos Tags: Review Article Source Type: research
Host modulation therapy with anti ‐inflammatory agents
Abstract
Host modulation therapy refers to a treatment concept in which drug therapies are used as an adjunct to conventional periodontal treatment to ameliorate destructive aspects of the host inflammatory response. This strategy is not new in the treatment of periodontitis. Previously, nonsteroidal anti‐inflammatory drugs have been investigated in this regard, with evidence of reductions in alveolar bone resorption when these drugs are used for prolonged periods of time. However, the risk of significant unwanted effects precludes the use of both nonselective nonsteroidal anti‐inflammatory drugs and the selective cycl...
Source: Periodontology 2000 - November 29, 2017 Category: Dentistry Authors: Philip M. Preshaw Tags: Review Article Source Type: research
Patient self ‐care of periodontal pocket infections
Abstract
Treatment of periodontitis aims to control the infection caused by the periodontal pathogenic flora and includes mechanical debridement of root surfaces to disrupt the supragingival and subgingival biofilm. As periodontal pockets of ≤ 5 mm can be perform in a stable condition and may not need additional therapy, the ability and the willingness of the patient to perform good oral hygiene on a long‐term basis are of utmost importance for ensuring long‐term success of periodontal treatment. In this context, the aim of all home‐care measures must be the optimal control of plaque biofilm in order to prevent or ...
Source: Periodontology 2000 - October 1, 2017 Category: Dentistry Authors: Nicole Birgit Arweiler, Thorsten M. Auschill, Anton Sculean Tags: Review Article Source Type: research
