Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Acute Exudative Polymorphous Paraneoplastic Vitelliform Maculopathy Managed With Intravitreal Aflibercept
In this report, we describe two patients with systemic cancer and AEPPVM who were treated with (Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye)
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Kaan G ündüz, MD Source Type: research

Aflibercept in Serous Foveal Detachment in Dome-Shaped Macula: Short-Term Results in a Retrospective Study
Dome-shaped macula (DSM) is an anterior convex elevation of the macula within a posterior myopic staphyloma as recently described by Gaucher et al.1 This particular anatomic feature can be found in 10% of highly myopic eyes. Generally, the DSM is asymptomatic, whereas vision loss and/or metamorphopsia may be complications of serous foveal detachment (SFD) or choroidal neovascularization (CNV).Some hypotheses have been postulated to explain the cause of serous detachment: many authors ascribe the convex macula to sclera thickening, which causes an alteration of the choroidal flow with (Source: Ophthalmic Surgery, Lasers and...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Giovanni Giacomelli, MD Source Type: research

The Impact of Switching Anti-Vascular Endothelial Growth Factor Therapy in the Management of Exudative Age-Related Macular Degeneration
Age-related macular degeneration (AMD) is the leading cause of blindness among elderly people older than 55 years of age in the developed world.1 Late-stage AMD consists of two types: exudative or neovascular AMD (nAMD) and AMD with geographic atrophy. Although late-stage AMD is infrequent among all reported cases of AMD, it is responsible for almost 90% of vision loss due to the disease.2 The introduction of anti-vascular endothelial growth factor (VEGF) therapy has changed the prognosis of nAMD and significantly decreased the incidence of legal blindness in some countries.3Three (Source: Ophthalmic Surgery, Lasers and Im...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Karen Jhi Wen Chia, FRCSEd Source Type: research

Treatment Burden in Neovascular AMD:Visual Acuity Outcomes are Associated With Anti-VEGF Injection Frequency
Seenu M. HariprasadPractical Retina Co-EditorIn this OSLI Retina Practical Retina column, Rehan M. Hussain, MD, and Thomas A. Ciulla, MD, MBA, discuss the association of injection frequency on visual outcome in exudative age-related macular degeneration.This topic has been studied and discussed extensively during the past 12 years. We have evolved from fixed monthly dosing regimens (not individualized) to pro re nata dosing regimens (somewhat individualized) to treat-and-extend dosing regimens (highly individualized). The American Society of Retina Specialists Preferences and Trends Survey (Source: Ophthalmic Surgery, Lase...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Rehan M. Hussain, MD Source Type: research

Acquired Nonpigmented Vitreous Cyst Associated With Lattice Degeneration
Vitreous cysts are rare ocular entities that can be pigmented or nonpigmented, free floating or fixed, asymptomatic or vision-impairing, congenital or acquired.1 They mainly occur in patients aged 10 years to 20 years (range: 5 years to 68 years), with the size ranged from 0.15 mm to 12 mm (most often, 2 mm to 5 mm).1 Treatments for the vitreous cyst depend on the subjective clinical symptoms, the cyst's location, and the patient's desire. Managements of symptomatic cysts with argon2,3 or YAG4,5 photocystotomy and pars plana vitrectomy6 –8 have been reported. Here, we report a case of a (Source: Ophthalmic Surgery, Laser...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Jing Lu, MD Source Type: research

Noninvasive, High-Resolution Functional Macular Imaging in Subjects With Retinal Vein Occlusion
Retinal vein occlusions (RVOs) are the second leading cause of blindness and common retinal morbidity occasioned by retinal vascular diseases worldwide, carrying a 15-year cumulative incidence of 1.8% and 0.5% for branch retinal vein occlusion (BRVO) and central retinal vein occlusion (CRVO), respectively.1,2 BRVO occurs more frequently with systemic hypertension,3,4 but the pathogenesis of retinal vein occlusion is still incompletely understood.5A glaring shortfall of existing modalities is quantitative blood flow measurements — a feature that may aid in understanding the (Source: Ophthalmic Surgery, Lasers and Imaging ...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Thalmon R. Campagnoli, MD Source Type: research

8 Questions with Darius Moshfeghi
Interview with R.V. Paul Chan, MD, MScDarius M. Moshfeghi, MD: Who has had the greatest influence on your career?R.V. Paul Chan, MD, MSc: Without a doubt, the people who have had the greatest influence on my career have been my parents. My father, Dr. Guy H. Chan, was Director of Resident Education at Wills Eye Hospital and then became Chairman of the Department of Ophthalmology at Temple University. He also invented the “Chan” wrist wrest that many of us use during surgery. My mother, Dr. Nongnart Romayananda Chan, is an ophthalmic pathologist, having trained with Dr. W. Richard Green at (Source: Ophthalmic Surgery, L...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: R.V. Paul Chan, MD, MSc Source Type: research

Improvement of Recalcitrant Diabetic Macular Edema After Peritoneal Dialysis
Diabetic macular edema (DME) is a leading cause of visual impairment among working-age adults globally.1 Known risk factors for DME include longer duration of diabetes, hyperglycemia, hypertension, dyslipidemia, and non-Hispanic black ethnicity.1,2 DME has also been found to be closely associated with diabetic nephropathy, since many of the pathologic processes driving microvascular sequelae in DME are likely to be similar.1 Herein, we describe a non-Hispanic white man with good blood pressure, glycemic, and lipid control who demonstrated a substantial improvement of his chronic DME, (Source: Ophthalmic Surgery, Lasers and...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Sally S. Ong, MD Source Type: research

A Modified Foveal Advancement Technique in the Treatment of Persistent Large Macular Holes
Vitrectomy was first introduced by Kelly and Wendel in 1991 to close macular holes (MHs).1 This technique is used to remove the anteroposterior vitreoretinal traction, which has been described as the primary mechanism responsible for MH formation.2,3 Many other additional surgical maneuvers have been developed to increase MH closure rate. Internal limiting membrane (ILM) peeling has been used in conjunction with vitrectomy to remove residual vitreous cortex and possible contraction of rigid ILM and to induce glial cell proliferation.4 The introduction of ILM peeling increased closure rates (Source: Ophthalmic Surgery, Lase...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: G ökhan Gurelik, MD Source Type: research

Pachychoroid Pigment Epitheliopathy Associated With Tamoxifen
Warrow et al. defined pachychoroid pigment epitheliopathy (PPE) as a new clinical entity. Its characteristic findings are reduced fundus tessellation, a variety of retinal pigment epithelium (RPE) abnormalities, absence of subretinal fluid, absence of drusen, and pachychoroid phenotype.1 Features of pachychoroid phenotype are choroidal hyperpermeability, dilated choroidal vessels (pachyvessels), and focal or diffuse increase in choroidal thickness. Dansingani et al. reported that choroidal thicknesses of eyes with pachychoroid phenotype are greater than 300 μm or they have an extrafoveal (Source: Ophthalmic Surgery, Laser...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Mehmet Giray Ersoz, MD Source Type: research

Cabbage Leaf Inverted Flap ILM Peeling for Macular Hole: A Novel Technique
Surgical treatment by vitrectomy, posterior vitreous detachment, and internal limiting membrane (ILM) peeling is the gold standard of treatment for full-thickness macular hole (FTMH), with closure rates of 90% to 98%.1 Chronic and large macular holes have the poorest surgical outcomes, with closure rates of 40% to 83%.2 In 2010, an inverted ILM flap technique was reported to increase the anatomical closure rates of large FTMH (diameter> 400 mm) to 98%.3 Since then, many studies have been reported with modifications in the original technique that help with better retention of the flap over (Source: Ophthalmic Surgery, Laser...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - October 16, 2017 Category: Opthalmology Authors: Ajay Aurora, MS Source Type: research

Venous Loop Reveals an Occult Retinoblastoma Tumor
Retinoblastoma is the most common primary malignant intraocular tumor in childhood. Clinical diagnosis and management are guided by dilated fundus examination, B-scan ultrasonography, and fluorescein angiography. Retinoblastoma tumors typically appear as elevated white or translucent masses, which may develop intratumoral calcifications, dilated feeder blood vessels, and change in reflectivity of the inner limiting membrane over the lesion. However, small tumors can be clinically “invisible” or under the detection threshold of clinical examination alone. These occult lesions have been (Source: Ophthalmic Surgery, Laser...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - September 14, 2017 Category: Opthalmology Authors: Katy C. Liu, MD, PhD Source Type: research

Terson Syndrome Associated With Acute Macular Neuropathy Type 2
Terson syndrome is demonstrated in patients following subarachnoid or intracranial hemorrhage.1 It is characterized by the presence of subretinal, intraretinal, subhyaloid, or intravitreal hemorrhages.2 These hemorrhage types may either be found in combination or in isolation. The most frequently associated cerebral abnormality in association with Terson syndrome is a ruptured intracranial aneurysm. This results in a rapid rise in intracranial pressure, forcing blood and/or cerebral fluid into the subarachnoid space encasing the optic nerves.3 The precise mechanism linking the intraocular (Source: Ophthalmic Surgery, Laser...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - September 14, 2017 Category: Opthalmology Authors: Stela Vujosevic, MD, PhD Source Type: research

Bilateral Retinal Detachments After Intravitreal Injection of Adipose-Derived ‘Stem Cells’ in a Patient With Exudative Macular Degeneration
Enthusiasm for stem cell treatment has given rise to numerous clinics in the United States offering unproven “stem cell” therapies without the oversight of the U.S. Food and Drug Administration (FDA). Though current FDA-regulated clinical trials are ongoing to evaluate the use of stem cell technology, unproven and unregulated “stem cell” therapies are already being offered to patients in hundreds o f clinics in the United States. In June 2016, the American Academy of Ophthalmology published a clinical statement warning that unproven “stem cell” therapies “require further scientific evaluation (Source: Ophthal...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - September 14, 2017 Category: Opthalmology Authors: Steven S. Saraf, MD Source Type: research

Switching Anti-VEGF Drugs in the Treatment of Diabetic Macular Edema
Anti-vascular endothelial growth factor (VEGF) therapy has become the first-line choice for center-involved diabetic macular edema (DME) treatment.1 Currently, three anti-VEGF drugs are routinely used in DME treatment: bevacizumab (Avastin; Genentech, South San Francisco, CA), ranibizumab (Lucentis; Genentech, South San Francisco, CA), and aflibercept (Eylea; Regeneron, Tarrytown, NY). Of these, only ranibizumab and aflibercept have U.S. Food and Drug Administration (FDA) approval for the treatment of DME, whereas bevacizumab is used off-label.1 –4 Despite the efficacy of these drugs in the (Source: Ophthalmic Surgery, L...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - September 14, 2017 Category: Opthalmology Authors: Touka Banaee, MD Source Type: research