Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Retinal Arteriovenous Malformation Assessment Using Swept-Source OCT Angiography
Wyburn Mason syndrome, also known as Bonnet-Dechaumme-Blanc syndrome, was first described in 1943.1 This syndrome is sporadic in nature with the involvement of brain in 30% of cases followed by skin, kidney, bone, and the muscles. These malformations are due to an embryonic vascular mesoderm abnormality extending from the retina to the mesencephalon. The diagnosis is mainly based on clinical findings revealing dilated tortuous retinal vessels extending from the optic disc to the retinal periphery. Spectral-domain optical coherence tomography (SD-OCT) and other modalities are able to delineate (Source: Ophthalmic Surgery, L...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - March 21, 2018 Category: Opthalmology Authors: Rohan Chawla, MD, FRCS (Glasg) Source Type: research

Swept-Source OCT Angiography of Multiple Evanescent White Dot Syndrome With Inflammatory Retinal Pigment Epithelial Detachment
Multiple evanescent white dot syndrome (MEWDS) is an acute inflammatory condition that is commonly associated with young women complaining of photopsias. Initially described by Jampol et al. in 19841, MEWDS presents with transient white dots on funduscopic exam, disruption of the photoreceptor-retinal pigment epithelium (RPE) layers on ophthalmic coherence tomography (OCT), and a wreath-like distribution of hyperfluorescent spots on fluorescein angiography (FA). Ordinarily, the RPE and choriocapillaris appear normal and normal choriocapillaris architecture has been confirmed on swept-source (Source: Ophthalmic Surgery, Las...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Swarup S. Swaminathan, MD Source Type: research

Outcomes of Intravitreal Bevacizumab and Diode Laser Photocoagulation for Treatment-Warranted Retinopathy of Prematurity
Retinopathy of prematurity (ROP) is a leading cause of preventable childhood blindness among low gestational age and low birth weight infants in the United States and is caused by the interruption of normal retinal angiogenesis.1 The landmark Cryotherapy for Retinopathy of Prematurity (CRYO-ROP) and Early Treatment of Retinopathy of Prematurity (ETROP) clinical trials showed that vision loss and other adverse outcomes could be prevented with early detection and intervention.2,3 Currently, the gold standard of treatment for ROP is diode laser photocoagulation (DLP), which halts the continued (Source: Ophthalmic Surgery, Las...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Tiffany A. Chen, BS Source Type: research

Low-Energy Stereotactic Radiotherapy for Treatment of Exudative Age-Related Macular Degeneration in a Treat-and-Extend Regimen
Age-related macular degeneration (AMD) is the leading cause of blindness in developed countries in people aged older than 50 years.1 Increased life expectancy, combined with the impact of risk factors such as arteriosclerosis, obesity, and smoking, means that the expected incidence will increase around two-fold by the year 2020.2 About one-tenth of those with AMD have the neovascular or “wet” form of the disease.3 The standard of care for wet AMD involves intravitreal injections of drugs that target vascular endothelial growth factor (VEGF), and the introduction of these therapies (Source: Ophthalmic Surgery, Lasers an...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Katja Hatz, MD Source Type: research

Swept-Source OCT Angiography of Full-Thickness Macular Holes: Appearance and Artifacts
Swept-source optical coherence tomography angiography (SS-OCTA) is a novel diagnostic tool enabling the presentation of en face images of retinal vessels at different retinal and choroidal layers. In this technique, the OCT signal is transformed to visualize flow. As in every imaging technique, artifacts may appear. Several of these were already described (eg, false-negative flow, false-positive flow, quilting defect, etc.)1 Their exact identification might improve our ability to correctly interpret the images we receive. The aim of the current study is to describe image artifacts that may (Source: Ophthalmic Surgery, Lase...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Zofia Michalewska, MD, PhD Source Type: research

Validity of the Red Reflex Exam in the Newborn Eye Screening Test Cohort
Early detection of neonatal ocular pathology is critical to avoid permanent preventable vision loss. The 2016 American Academy of Pediatrics (AAP) policy statement and clinical report recommend red reflex testing in addition to external inspection of lids and eyes for all newborns.1,2 Pupil examination and visual acuity fix-and-follow response are recommended prior to 6 months of age, whereas photoscreening and handheld autorefraction for amblyogenic refractive error are recommended in children 6 months to 3 years of age.1 –3 This policy replaced the 2008 AAP policy statement solely (Source: Ophthalmic Surgery, Lasers an...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Cassie A. Ludwig, MD, MS Source Type: research

Sheets Glide-Assisted Intraocular Placement of the Argus II Retinal Prosthesis
We present a technique to deal with difficult intraocular placement of the electrode array through a sclerotomy in a patient with retinitis (Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye)
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Avni P. Finn, MD, MBA Source Type: research

Use of Optical Coherence Tomography Angiography in Masqueraders of Wet Age-Related Macular Degeneration and Choroidal Neovascularization
Seenu M. Hariprasad Practical Retina Co-EditorThe role of optical coherence tomography angiography (OCTA) in the evaluation of the retinal and choroidal vasculature is much better understood today compared to its introduction in our clinics several years ago. Since 2015, we have seen numerous papers published comparing OCTA to conventional fluorescein angiography to evaluate various retinal disease states. Retina specialists are finally starting to process this flood of data.I asked Dimitra Skondra, MD, PhD, Sidney Schechet, MD, and Asadolah Movahedan, MD, to provide us with an overview of (Source: Ophthalmic Surgery, Lase...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Sidney Schechet, MD Source Type: research

Paradoxical Anatomic Response to Topical Carbonic Anhydrase Inhibitor in X-linked Retinoschisis
Juvenile, or X-linked, retinoschisis (XLRS) is a relatively uncommon cause of macular degeneration in young men.1 This condition is caused by mutations in the RS1 gene, which encodes for the protein retinoschisin.1,2 The schisis, or splitting, typically occurs within the inner retinal layers, leading to visual deterioration. There is characteristically a spoke-wheel pattern of folds radiating from the fovea and peripheral bullous retinal elevations, usually in the inferotemporal quadrant.1,2 The clinical presentation of X-linked retinoschisis is greatly variable, even among patients with the (Source: Ophthalmic Surgery, La...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Brandon Menke, MD Source Type: research

Optical Coherence Tomography Microangiography Imaging of Circumscribed Choroidal Hemangioma
Choroidal hemangioma is a smooth, red-orange, typically unilateral, benign vascular tumor that occurs in either a circumscribed or a diffuse form, the latter of which is associated with Sturge-Weber syndrome.1 The lesions have been suggested to be congenital; however, the pathogenesis and incidence is unknown.2 Although the tumor may be asymptomatic and undetected by cursory fundus examination, submacular or juxtapapillary lesions often result in decreased visual acuity due to macular edema, serous retinal detachments, or subretinal fibrosis during the second to fifth decades of life.2 –4 (Source: Ophthalmic Surgery, Las...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Adam R. Sweeney, MD Source Type: research

Microscope-Integrated Intraoperative Ultrahigh-Speed Swept-Source Optical Coherence Tomography for Widefield Retinal and Anterior Segment Imaging
Optical coherence tomography (OCT) is a noninvasive imaging method that has become critical for diagnosis and management of ocular pathology due to its ability to generate high-resolution, depth-resolved images of the retina, optic nerve, and anterior segment.1 Intraoperative OCT enables high-resolution visualization of intraocular details that cannot be visualized through the microscope alone and may be useful to plan surgery, track surgical maneuvers, assess outcomes, and potentially impact surgical decision-making.2Researchers from Duke University were the first to demonstrate a (Source: Ophthalmic Surgery, Lasers and I...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Chen D. Lu, MS Source Type: research

Optical Coherence Tomography Angiography of the Macula in Adults With a History of Preterm Birth
The acute phase of retinopathy of prematurity (ROP) occurs in infancy; however, sequelae of ROP is lifelong. The incidence of ocular diseases, including high refractive error, strabismus, cataracts, glaucoma, and retinal detachment, is higher in children with a history of ROP, even after proper treatment.1 –3 Optical coherence tomography (OCT) studies have shown that eyes with ROP may have several structural changes, including retention of inner retinal layers at the foveal center, absence of foveal pit, and cystoid changes.4,5Optical coherence tomography angiography (OCTA) is a noninvasive (Source: Ophthalmic Surgery, L...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Khalil Ghasemi Falavarjani, MD Source Type: research

Detection of Choriocapillaris Loss in Alport Syndrome With Swept-Source OCT Angiography
Alport Syndrome (AS) is a genetic condition caused by mutations in Collagen IV, specifically in the COL4A3, COL4A4, and COL4A5 genes. Collagen IV is expressed within basement membranes as three different heterotrimers: α1α1α2, α3α4α5, α5α5α6.1 The α3α4α5 heterotrimer is present in the adult glomerulus, cochlea, cornea, lens capsule, and retina,2 whereas the α5α5α6 isoform is highly expressed in vascular connective tissue.3 Anterior segment ocular manifestations of AS include recurrent corneal erosio ns,2 posterior polymorphous corneal dystrophy, anterior lenticonus, and anterior polar (Source: Ophthalmic Sur...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Swarup S. Swaminathan, MD Source Type: research

Active Cone Regeneration Following Autologous Internal Limiting Membrane ‘Chunk’ Transplantation in Optic Disc Pit-Associated Maculopathy
Congenital optic nerve head pits affect fewer than one person in a population of 10,0001 and are found to be bilateral in 10% to 15% of cases, whereas 25% to 75% of cases with optic disc pit develop serous macular detachment2 –3 and retinoschisis within the second to fourth decades of life. There is no consensus regarding the indications for surgical intervention or the methods and techniques of surgery. Multiple surgical techniques have been described for persisting optic disc pit maculopathy (ODPM),4–7 but not one of the techniques has been proven to be better than the others. Moreover, (Source: Ophthalmic Surgery, L...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - February 15, 2018 Category: Opthalmology Authors: Aditya Modi, DNB, FRVS Source Type: research

A New OCT Finding in Purtscher-Like Retinopathy
Purtscher retinopathy (PR) is a rare condition first described in 1910 by Otmar Purtscher in a middle-aged man with severe head trauma who presented with visual loss in both eyes. Purtscher observed multiple areas of retinal whitening (Purtscher flecken) and intraretinal hemorrhages in the posterior pole of both eyes.1After its original description, similar fundus appearance was observed in patients with numerous diseases including acute pancreatitis, fat embolization, childbirth, renal failure, and connective tissue disorders.2 –8 Since PR's original description involved trauma, primarily (Source: Ophthalmic Surgery, La...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Sevil Ari Yaylali, MD, FEBO, FICO Source Type: research