Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye RSS feedThis is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Chorioretinal Perfusion in Persistent Placoid Maculopathy
Persistent placoid maculopathy (PPM) is a rare clinical entity, first reported by Golchet et al. in 2007.1 PPM was described with the presence of well-defined, plaque-like lesions involving the macula that spared the peripapillary zone with a characteristic appearance on fluorescein angiography (FA) and indocyanine green angiography (ICGA).Although PPM has been described with clinical features resembling those of other maculopathies, including serpiginous choroiditis, relentless placoid chorioretinitis, and acute posterior multifocal placoid pigment epitheliopathy,2 –4 the etiology of this (Source: Ophthalmic Surgery, La...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Th érèse M. Sassalos, MD Source Type: research

Choroidal Thickness Change in Patients With Diabetic Macular Edema
Diabetic macular edema (DME) is a leading cause of visual impairment in individuals of working age.1 The pathogenesis of DME has long been attributed to retinal vascular hyperpermeability that is seen on fluorescein angiography. Clinical and experimental findings suggested that choroidal vasculopathy in diabetes may play a role in the pathogenesis of diabetic retinopathy.2,3Various choroidal abnormalities, including loss of the choriocapillaris, increased tortuosity, narrowing and dilation of vessels, and sinus-like structure formation between choroidal lobules, have been reported in previous (Source: Ophthalmic Surgery, L...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Tamer F. Eliwa, MD, FRCS Source Type: research

Whether to Ignore the Macular Hole in a Uveitic Patient: A Discussion of the Pros and Cons of Elective Macular Surgery in a Challenging Population
Howard F. Fine, Practical Retina Co-EditorOften, surgery in a patient with uveitis is deferred as long as possible to avoid inflammatory complications. The difficulty typically lies not in the technical aspects of the procedure, but often in the perioperative management to avoid recurrences of and complications from uveitis.However, modern vitreoretinal surgery has evolved to employ minimally invasive approaches that incur only minimal postoperative inflammation in routine cases. Because of these advances, the risk-benefit ratio has changed over time for these complex cases.The literature on (Source: Ophthalmic Surgery, La...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Shree K. Kurup, MD Source Type: research

Optical Coherence Tomography in Patients With the Subretinal Implant Retina Implant Alpha IMS
Retinal implants attempt to partially restore very low vision in legally blind patients with end-stage hereditary retinal dystrophies whose visual function is reduced to perception of light or less.1In advanced stages of hereditary retinal dystrophies, such as retinitis pigmentosa, a profound loss of photoreceptors occurs.2 The neural mechanisms proximal to the photoreceptors, specifically the bipolar cells and ganglion cells, however, may be sufficiently preserved to convey information to the brain. This condition is utilized in retinal prosthetic devices attempting to partially restore (Source: Ophthalmic Surgery, Lasers...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Laura Kuehlewein, MD Source Type: research

Non-Mydriatic Ultra-Widefield Imaging Compared With Single-Field Imaging in the Evaluation of Peripheral Retinal Pathology
Retinal imaging is an important adjunct to the diagnosis, management, and monitoring of various posterior segment conditions. Traditionally, single-field fundus photography is used to evaluate and monitor diseases primarily involving the posterior pole, such as macular degeneration, glaucoma, and optic neuropathy, among others. It effectively captures the posterior pole, including the macula and optic nerve, covering a 20 ° to 50° field of view. It is also routinely used for the diagnosis, treatment, and monitoring of posterior segment conditions that may extend beyond the posterior pole, such (Source: Ophthalmic Surgery...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Mehreen Adhi, MD Source Type: research

Valved 25-Gauge Cannula for Vitreous Tap and Injection
When infectious endophthalmitis is suspected, a vitreous tap and intravitreal injection of antibiotics are often employed to obtain a specimen for diagnosis and administer treatment. This in-office procedure normally consists of introducing a short 25- or 27-gauge needle on a 5-mL or 10-mL syringe 3 mm to 4 mm posterior to the limbus of an anesthetized eye using standard sterile technique.1 Gentle suction is manually applied to withdraw a vitreous sample to be sent to the laboratory for microbiologic analysis. Next, multiple intravitreal injections of antibiotics and/or steroid are (Source: Ophthalmic Surgery, Lasers and I...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Theodore Leng, MD, MS Source Type: research

Treatment of Ipilimumab-Induced Vogt-Koyanagi-Harada Syndrome With Oral Dexamethasone
Ipilimumab (Yervoy; Bristol-Myers Squibb, New York City, NY) is a human monoclonal antibody to cytotoxic T-lymphocyte antigen 4 (CTLA-4) and has been shown to increase median survival in patients with unresectable metastatic melanoma1 and stage 3 melanoma after surgical resection.2 The U.S. Food and Drug Administration (FDA) approved ipilimumab for the treatment of unresectable or metastatic melanoma in 2011. By inhibiting CTLA-4, which is an innate inhibitor of T-cell costimulation, ipilimumab is able to potentiate the host's immune system and promote T-cell proliferation against malignant (Source: Ophthalmic Surgery, Las...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Matthew T. Witmer, MD Source Type: research

DualTrack Technology Improves Optical Coherence Tomography Angiography Image Quality
Optical coherence tomography angiography (OCTA) allows visualization of ocular vessels by detecting motion contrast from flowing blood. Motion contrast can be detected by two different validated methods: the “speckle decorrelation,” which detects intensity changes in OCT structural image, and the “phase variance,” which assesses changes in the phase of light wave.1–7OCT samples a discrete tissue volume and generates a numerical value based on the reflectivity of the volume. This numerical value corresponds to a voxel (that is a portmanteau of “volume” and “pixel”) in the image displayed. Each (Source: Oph...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Luigi A. De Vitis, MDs Source Type: research

Navigating the Options for the Treatment of Intraocular Lens Malposition
Howard F. Fine, Practical Retina Co-EditorThere has been a wave of new and innovative techniques for vitreoretinal surgeons in the management of aphakia as well as subluxed or dislocated intraocular lenses (IOLs). Several of these techniques are quite elegant and fun to perform, but most incur a learning curve to master. Having a number of these options available is crucial to maximizing patient outcomes when presented with varying clinical scenarios.Our anterior segment colleagues are often extremely grateful for our assistance with these cases, for example when rescuing a “premium IOL” (Source: Ophthalmic Surgery, La...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Dimosthenis Mantopoulos, MD, PhD Source Type: research

Swept-Source Optical Coherence Tomography Angiography Findings in Torpedo Maculopathy
We describe features detected on OCT angiography (OCTA) in two cases of torpedo maculopathy using swept-source OCTA technology (DRI OCT Triton; Topcon Medical Systems, Oakland, NJ).A 19-year-old asymptomatic female with visual acuity (VA) of 6/7.5 in the right eye and 6/6 in the left eye was noted to have a (Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye)
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Zaria Ali, MBChB Source Type: research

Comparison of Pneumatic Retinopexy and Scleral Buckle for Primary Rhegmatogenous Retinal Detachment Repair
The scleral buckle procedure (SBP) was pioneered by Charles Schepens in 1957 and revolutionized the treatment of patients with retinal detachment.1 In comparison to the 30% to 40% success rates initially reported by Gonin,2 scleral buckling has been reported to result in anatomic reattachment in up to 94% of uncomplicated retinal detachment cases.3 The surgery also offers significant longevity, with anatomic success lasting 20 years or more in the large majority of cases.4Pneumatic retinopexy (PR) was introduced by Hilton and Grizzard in 1986. PR allows surgeons to potentially avoid some of (Source: Ophthalmic Surgery, Las...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Yannis M. Paulus, MD Source Type: research

Single-Spot Yellow Laser Versus Conventional Green Laser on Panretinal Photocoagulation: Patient Pain Scores and Preferences
Proliferative diabetic retinopathy remains a leading cause of visual impairment in economically active populations in developing, as well as developed, countries. It results in 12,000 to 24,000 new cases of blindness each year in the United States.1,2 Diabetic visual impairment might be prevented by two main strategies: early diabetic retinopathy diagnosis and panretinal photocoagulation (PRP) therapy.1 Many multinational trials have shown the benefits of PRP in high-risk proliferative diabetic retinopathy (PDR), where a reduction of severe visual loss in up to 60% of cases has been (Source: Ophthalmic Surgery, Lasers and ...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Gerardo Gonz ález-Saldivar, MD Source Type: research

Irvine-Gass Macular Edema Responding to the Combination of Oral Mineralocorticoid-Receptor Antagonist With Dexamethasone Drops
Postoperative macular edema (ME), also termed pseudophakic ME or “Irvine-Gass syndrome,”1,2 is a vision-limiting complication occurring after intraocular surgery. Its frequency is estimated at 1.2% after routine cataract extraction3 and is probably higher following complex anterior or posterior segment procedures. Diabetes, lens capsule rupture, history of ep iretinal membrane, uveitis, retinal vein occlusion, or retinal detachment are known risk factors.3 On average, affected eyes harbor worse postoperative visual acuity (VA).3,4 Several treatments have been used, including oral (Source: Ophthalmic Surgery, Lasers and...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Alexandre Matet, MD Source Type: research

Quantitative Choriocapillaris Perfusion Before and After Vitrectomy in Idiopathic Epiretinal Membrane by Optical Coherence Tomography Angiography
An epiretinal membrane (ERM), also known as macular pucker or cellophane maculopathy, first described in 1865, is an avascular, fibrocellular membrane that proliferates on the inner surface of the retina.1,2 The most common presenting symptoms include decreased visual acuity and metamorphopsia,1 which seriously impair quality of life. Without clear pathogenesis of the disease, idiopathic epiretinal membrane (iERM) mainly occurs in patients older than 50 years of age.2,3 The prevalence of iERM varies from 1.02% to 7.3% based on studies conducted in different parts of China.4 –7 Previous studies (Source: Ophthalmic Surgery...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: Yanping Yu, MD Source Type: research

Optical Coherence Tomography Findings in Endogenous Fungal Chorioretinitis, Retinitis, and Endophthalmitis
Patients with a history of diabetes, indwelling lines/catheters, hyperalimentation, or immunocompromise are at increased risk for fungal bloodstream infections.1 –3 Fungemic patients are subject to a variety of pathologic manifestations related to fungal dissemination and end organ damage, including chorioretinitis and endophthalmitis via hematogenous seeding of small retinal and choroidal capillaries. As has been demonstrated pathologically, localized ocu lar fungal proliferation can progress to focal or multifocal inflammatory lesions involving the retina and/or choroid along with subsequent (Source: Ophthalmic Surgery...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - November 13, 2017 Category: Opthalmology Authors: John D. Stephens, MD Source Type: research