Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

New Paradigms in Polypoidal Choroidal Vasculopathy Management: The Impact of Recent Multicenter, Randomized Clinical Trials
Seenu M. Hariprasad Practical Retina Co-EditorJust as recently as 2 years ago, in this column, we asked Colin S. Tan, MBBS, MMed (Ophth), FRCSEd (Ophth), and Louis W. Lim, MBBS, to summarize the optimal management of polypoidal choroidal vasculopathy (PCV). Since that time, there have been several randomized clinical trials that have given us further insight on the management of this interesting condition. PCV was once considered to be a variant of wet age-related macular degeneration (AMD). However, it is clear that the unique clinical features and high prevalence in pigmented individuals (Source: Ophthalmic Surgery, Lase...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Colin S. Tan, MBBS, MMed (Ophth), FRCSEd (Ophth) Source Type: research

PRN Ranibizumab in the Treatment of Choroidal Neovascularization Secondary to Ocular Histoplasmosis
Ocular histoplasmosis syndrome (OHS) is a systemic disease thought to be caused by the inhalation and systemic spread of the dimorphic fungal organism Histoplasma capsulatum. A mild systemic infection occurs after the initial infection and results in granulomatous inflammation and resultant encapsulation primarily in the lungs and the choroid. The classic ocular findings for OHS include peripheral chorioretinal scarring ( “histo spots”), peripapillary atrophy and hyperplasia, and maculopathy (or choroidal neovascularization [CNV]). The development of CNV is the primary ocular complication (Source: Ophthalmic Surgery, L...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Edward H. Wood, MD Source Type: research

Segmental Analysis of Macular Layers in Patients With Rhegmatogenous Retinal Detachment Treated With Perfluoropropane or Silicon Oil
Optical coherence tomography (OCT) imaging is commonly used in diagnosing and monitoring retinal diseases. New developments in OCT have improved the quality of the acquired images1 and allow automatic measurements of intraretinal layers. A new update for the Spectralis (Heidelberg Engineering, Heidelberg, Germany), the Heidelberg Eye Explorer mapping software (version 6.0c) allows quantitative measurements of individual retinal layers such as the nerve fiber layer (NFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer (Source: Ophthalmic Surgery, Lasers ...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Yasin Sakir Goker, MD Source Type: research

Double Optic Disc Pit With Glial Plugs Imaged by Wide-Field Optical Coherence Tomography
Optic disc pits (ODPs) are rare congenital anatomic defects in the optic disc present in one in 11,000 individuals. ODPs belong to a broader spectrum of congenital optic disc abnormalities, including optic disc coloboma, morning glory disc anomaly, and extrapapillary excavation.1 Cases of more than one ODP in the same eye are extremely rare, with only four reported cases in the literature.2 –5 Double ODPs tend to be on the same side of the optic disc (temporally or inferotemporally), raising the possibility that they originate from the same underlying laminar defect. To our knowledge, only two (Source: Ophthalmic Surgery...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Ismini Koulouri, MD Source Type: research

The Prevalence of Adverse Ocular Hemorrhagic Events in Patients Utilizing Oral Anticoagulant and Antiplatelet Therapy in Routine Clinical Practice
Currently, more than 6 million patients receive long-term antithrombotic therapy in the United States.1 Newer oral anticoagulants such as dabigatran (Pradaxa; Boehringer Ingelheim, Ingelheim am Rhein, Germany), rivaroxaban (Xarelto; Janssen Pharmaceuticals, Beerse, Belgium), and apixaban act by directly inhibiting factor Xa or thrombin.2 Second- and third-generation oral antiplatelet medications include clopidogrel (Plavix; Bristol-Myers Squibb, New York City, NY), prasugrel (Effient; Lilly Medical, Indianapolis, Indiana), and ticagrelor (Brilinta; AstraZeneca, Cambridge, UK), which function (Source: Ophthalmic Surgery, La...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Dattanand M. Sudarshana, BS Source Type: research

Blau-Jabs Syndrome in a Tertiary Ophthalmologic Center
Blau-Jabs syndrome (BJS), first described simultaneously by Blau and Jabs in 1985, is an autosomal dominant chronic inflammatory syndrome defined by early onset of noncaseating granulomatous dermatitis, arthritis, and uveitis.1,2 The disease is rare, with fewer than 200 cases reported by 2015, most of them with onset in white patients younger than 4 years of age.3 –5 The main differential diagnosis is sarcoidosis.4,5 BJS is distinguished from sarcoidosis by the absence of pulmonary involvement and adenopathies, the arthritis pattern, and familial inheritance6 related to the CARD15 (caspase (Source: Ophthalmic Surgery, La...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Heloisa Nascimento, MD Source Type: research

Propranolol for Proliferative Diabetic Retinopathy
Proliferative diabetic retinopathy (PDR) is a complication of long-standing and poorly controlled diabetes mellitus (DM). PDR is the most advanced stage of diabetic retinopathy (DR) and is heralded by the presence of ocular neovascularization. Alongside optimization of glycemic control and other systemic factors, standard treatment of high risk PDR involves application of laser burns to the peripheral retina with panretinal photocoagulation (PRP).1 PRP reduces the risk of vision loss and represents the current gold standard therapy for this condition. Unfortunately, neovascular activity (Source: Ophthalmic Surgery, Lasers ...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Andrew M. Hendrick, MD Source Type: research

An Evaluation of the Relationship Between Clinically Unilateral Pseudoexfoliation Syndrome and Age-Related Macular Degeneration
Pseudoexfoliation (PEX) syndrome (XFS) is characterized by the production and progressive accumulation of fibrillar extracellular material in many ocular tissues, including the lens capsule, zonules, iris, and anterior chamber angle.1 –8 Recent studies have demonstrated that age-related macular degeneration (AMD) is associated with the presence of XFS and have emphasized that PEX and AMD share common predisposing factors with similarities in epidemiological features and pathogenesis.1,2 Similarly, in our clinical practice, we h ave observed that the rate of wet AMD in eyes with clinically (Source: Ophthalmic Surgery, Las...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Mehmet Ozgur Zengin, MD Source Type: research

Small-Gauge Endoscopy-Guided Pneumatic Anterior Hyaloid Detachment: A New Surgical Technique for Combined Pars Plana Vitrectomy and Pars Plana Glaucoma Drainage Implant
Glaucoma drainage implants (GDIs) are usually indicated for the treatment of eyes with glaucoma uncontrolled by topical and oral medications. Pars plana GDIs are considered in specific cases where there is a risk of complications associated with the insertion of GDIs in the anterior chamber (AC). These indications may include eyes with very narrow AC, failure of GDI placed in the AC, pre-existing corneal disease, or angle neovascularization.1,2 This approach decreases the rate of perioperative and postoperative complications related to GDI insertion (including hyphema). Complete removal of (Source: Ophthalmic Surgery, Lase...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Ali Dirani, MD Source Type: research

Multimodal Imaging Including Optical Coherence Tomography Angiography of a Patient With Argus II Retinal Prosthesis One Year After Implantation
The Argus II Retinal Prosthesis System (Second Sight Medical Products, Sylmar, CA) is a surgically implantable device designed to provide artificial vision to patients with outer retinal degenerative diseases, especially retinitis pigmentosa (RP). The system was first assessed in 30 blind subjects, 28 of whom had end-stage RP, in an international clinical trial.1 The patients were evaluated by color fundus photography, fluorescein angiography (FA), and optical coherence tomography (OCT) during the follow-up, and the long-term safety results were found acceptable. After U.S. Food and Drug (Source: Ophthalmic Surgery, Lasers...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Dilek G üven, MD Source Type: research

Hemorrhagic Ischemic Retinal Vasculitis and Alopecia Areata as a Manifestation of HLA-B27
We describe a patient who presented with alopecia areata and retinal (Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye)
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - January 10, 2018 Category: Opthalmology Authors: Ravi Sharma, BS Source Type: research

A Frag Bag for Efficient Removal of Dislocated Nuclear Material
Posterior dislocation of the entire crystalline lens or nuclear fragments into the vitreous cavity may occur as a complication of cataract surgery, closed globe injury, connective tissue disorders, or other systemic conditions. Pars plana vitrectomy with phacofragmentation is a commonly utilized technique for removal of lens material from the vitreous cavity.1 However, the enlargement of one or more sclerotomies to accommodate the 20-gauge phacofragmatome in the era of smaller-gauge vitreous surgery may increase the risk of postoperative hypotony, vitreous incarceration, retinal detachment, (Source: Ophthalmic Surgery, Las...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Duncan E. Berry, MD Source Type: research

Characteristics of the Choriocapillaris Layer in Optical Coherence Tomography Angiography of Acute Central Serous Chorioretinopathy
Central serous chorioretinopathy (CSC) is a chorioretinal disease. Diffuse or focal dysfunction of the retinal pigment epithelium (RPE) is led by increased permeability from the choriocapillaris, which in turn causes a detachment of the neurosensory retina.1 –6 Albrecht first discovered this disease in 1866, known as central recurrent retinitis. Subsequently, the name underwent a series of changes, before finally being denoted as “central serous chorioretinopathy” by Gass et al. in 1967.1Nowadays, a large number of people, especially the middle-aged, suffer from this vision threat. Since the (Source: Ophthalmic Surge...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Yi Qu, MD Source Type: research

Outer Retinal Changes on Spectral-Domain Optical Coherence Tomography Pre- and Post-Silicone Oil Removal
Vision loss associated with intraocular silicone oil (SiO) tamponade may be the result of various factors, such as optic neuropathy and retinal toxicity, although the exact pathophysiology remains unclear.1 –5 Histopathologic studies have correlated the presence of SiO droplets within ocular tissues, including the iris, retina, trabecular meshwork, ciliary body, and epiretinal membranes (ERMs), with associated localized inflammation.6,7 Additionally, anterior segment pathology such as glaucoma, catar act, and keratopathy are known complications of prolonged SiO tamponade.8–10The risk for (Source: Ophthalmic Surgery, La...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Alia K. Durrani, MD Source Type: research

Positive Visual Phenomena Following Implantation of the Argus II Retinal Prosthesis
The Argus II Retinal Prosthesis System (Second Sight Medical Products, Sylmar, CA) is the only U.S. Food and Drug Administration-approved implantable to date to restore vision in blind patients with retinitis pigmentosa (RP).1,2 The device consists of a spectacle-mounted camera that records the environment images and transfers light stimuli to a video processing unit that converts the light to pulsatile electronic signals forming a brightness map. The electronic signals are transferred to an array of 60 electrodes fixated to the surface of the retina in the macula. The surviving inner retinal (Source: Ophthalmic Surgery, L...
Source: Ophthalmic Surgery, Lasers and Imaging : the Official Journal of the International Society for Imaging in the Eye - December 19, 2017 Category: Opthalmology Authors: Ama Sadaka, MD Source Type: research