Candida auris colonization in an immunocompetent patient: A new threat in medical ICU
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Shukla Das, Richa Tigga, Gargi Rai, Praveen Kumar Singh, Shyama Datt, Asha Tyagi, Narendra Pal SinghAbstractCandida auris has become a great challenge in diagnostic, therapeutic and hospital environmental adaptation. With a prevalence of 5.3% in intensive care unit (ICU) acquired candidemia in India, its colonization is very rapid which hastens hospital transmission. Strict surveillance and preventive measures need to be adopted in ICU as it can persist on dry, inanimate object, prompt adaptation and antifungal resistance can pose a ...
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research
Vascular pythiosis of carotid artery with meningitis and cerebral septic emboli: A case report and literature review
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Maria Nina Chitasombat, Porkaew Petchkum, Suthas Horsirimanont, Pattana Sornmayura, Ariya Chindamporn, Theerapong KrajaejunAbstractVascular Pythiosis caused by Pythium insiodiosum rarely involves carotid artery. A case of concealed ruptured pseudoaneurysm of the carotid artery with neck abscesses, and cerebral septic emboli is described. Patient presented with large pulsatile neck mass that failed to response to surgery, antifungals and immunotherapeutic vaccine. Residual unresectable disease leads to death in the patient. Pythiosis ...
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research
Incidental findings of blastomycosis lung nodules in five asymptomatic patients
In this report we describe five sporadic cases of blastomycosis in asymptomatic patients. All of these cases were initially identified as incidental findings of lung nodules on CXR or CT. To our knowledge, these are the first detailed descriptions of asymptomatic blastomycosis, occurring as sporadic disease, in the literature. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research
T2Candida® to guide antifungal and lengh of treatment of candidemia in a pediatric multivisceral transplant recipient
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Iker Falces-Romero, Emilio Cendejas-Bueno, María Laplaza-González, Luis Escosa-García, Cristina Schuffelmann-Gutiérrez, Belén Calderón-Llopis, Javier Pemán, Pedro de la Oliva, Julio García-RodríguezAbstractA case of 1-year- old male multivisceral transplant recipient with candidemia diagnosed by the T2Candida® test is presented. Optimal management of the candidemia complemented the treatment of the global clinical episode. Duration of treatment might be established much more precisely with the T2Candida® test than with blo...
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research
A case of disseminated sporotrichosis caused by Sporothrix brasiliensis
Publication date: Available online 21 March 2018 Source:Medical Mycology Case Reports Author(s): Rachel Basques Caligiorne, Blenda Fernandes, Dayana Monteiro Coutinho, Renata R. Gomes, Amanda Sanchez Machado, Emanoelle Fernandes Rutren La Santrer, Maria Silvia Laborne, Mauricio Buzelin Nunes, Vania A. Vicente, Sybren de Hoog This paper presents a case of disseminated sporotrichosis in a 13-year-old female, originating from a rural area in Minas Gerais state, Brazil. The patient was hospitalized with hyporexia, prostration, fever and disseminated ulcerative lesions, besides anemia, leucopenia and sepsis of proba...
Source: Medical Mycology Case Reports - March 21, 2018 Category: Biology Source Type: research
Near-fatal mucormycosis post-double lung transplant presenting as uncontrolled upper gastrointestinal haemorrhage
We present a case of splenic mucormycosis post-double lung transplant, presenting as uncontrolled near-fatal upper gastrointestinal haemorrhage, to remind clinicians of the need to consider pre-transplant invasive fungal infection risk factors if an unexpected fungal infection arises in the post-transplant period. This case also highlights the valuable contribution of molecular technology for fungal identification but also the need for clinical correlation. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - March 20, 2018 Category: Biology Source Type: research
A case of pulmonary cryptococcoma due to Cryptococcus gattii in the United Kingdom
We report a case of Cryptococcus gattii infection in the UK in a 76-year-old woman on biologic therapy for intra-abdominal non-Hodgkin lymphoma. An incidental nodular lung lesion was found on a chest imaging and histology, culture and molecular mycology studies of the lobectomy specimen revealed the presence of C. gattii. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - March 20, 2018 Category: Biology Source Type: research
Lomentospora prolificans vertebral osteomyelitis with spinal epidural abscess in an immunocompetent woman: Case report and literature review
We report a case of L. prolificans thoracic vertebral osteomyelitis with spinal epidural abscess in a patient without apparent immunodeficiency. Clinical manifestations and radiographic findings could not distinguish from other etiologic agents. Treatment is also challenging because L. prolificans is usually resistant to antifungal agents. The patient underwent surgical debridement and has been receiving a prolonged combination of antifungal therapy to prevent an infection relapse. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - March 20, 2018 Category: Biology Source Type: research
Microbiological and immunological characteristics of a lethal pulmonary Aspergillus niger infection in a non-neutropenic patient
Publication date: Available online 7 March 2018 Source:Medical Mycology Case Reports Author(s): Jessica D. Workum, Suzanne W. de Jong, Mark S. Gresnigt, Katharina L. Becker, Peter Pickkers, Frank L. van de Veerdonk, Yvonne F. Heijdra, Eva Kolwijck Invasive pulmonary aspergillosis is increasingly described in non-neutropenic patients, such as patients with COPD receiving corticosteroids and the critically ill. Here, we present a case of a lethal pulmonary Aspergillus niger infection in a COPD patient. Immunological tests showed an impaired innate and adaptive immune response to Aspergillus. A history of COPD, unre...
Source: Medical Mycology Case Reports - March 8, 2018 Category: Biology Source Type: research
Two Cases of Fungal Keratitis Caused by Metarhizium anisopliae
We present two cases of keratitis due to Metarhizium anisopliae in geographically separated areas of the United States. The isolates were microscopically similar but morphologically different and were identified by ribosomal DNA sequencing. Both isolates had low minimum inhibitory concentration (MIC) values to caspofungin and micafungin, but high MIC values to amphotericin B. The morphologic and antifungal susceptibility differences between the two isolates indicate possible polyphylogeny of the group. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - March 7, 2018 Category: Biology Source Type: research
Subcutaneous abscesses caused by Trichophyton rubrum in the unilateral groin of an immunocompromised patient: A case report
Publication date: Available online 6 March 2018 Source:Medical Mycology Case Reports Author(s): Utako Okata-Karigane, Yasuki Hata, Emiko Watanabe-Okada, Shunichi Miyakawa, Michi Ota, Yutaka Uzawa, Shigekazu Iguchi, Atsushi Yoshida, Ken Kikuchi A 60-year-old Japanese man presented with multiple subcutaneous nodules in his left groin. Histologically, the nodules consisted of suppurative granulomas and abscesses not involving the hair follicles. Trichophyton rubrum TWCC57922 was detected by fungal culture and polymerase chain reaction (PCR) sequencing of the rDNA genes. We diagnosed these nodules as deeper dermal d...
Source: Medical Mycology Case Reports - March 7, 2018 Category: Biology Source Type: research
Invasive pulmonary mucormycosis and aspergillosis in a patient with decompensated hepatic cirrhosis
This report also highlights the first non-diabetic case of invasive pulmonary mucormycosis with decompensated hepatic cirrhosis. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - March 7, 2018 Category: Biology Source Type: research
Severe acute respiratory distress syndrome in a liver transplant patient
Publication date: Available online 6 March 2018 Source:Medical Mycology Case Reports Author(s): Nicholas M. Moore., Laurie A. Proia This case report presents a 46-year old man with a failed liver transplant who presented with malaise and dyspnea. Imaging studies revealed diffuse reticulonodular infiltrates and innumerable miliary nodules and a left upper lobe consolidative mass. Examination of bronchoalveolar lavage fluid demonstrated yeast cells with broad-based budding. He was diagnosed with pulmonary blastomycosis and started therapy with liposomal amphotericin. In spite of therapy, he clinically worsened, developin...
Source: Medical Mycology Case Reports - March 7, 2018 Category: Biology Source Type: research
Blastomycosis in a Renal Transplant Recipient: Case of Immune Reconstitution Inflammatory Syndrome
Publication date: Available online 1 March 2018 Source:Medical Mycology Case Reports Author(s): Alexis Guenette, Shahid Husain, Ana Konvalinka, William Geddie, Coleman Rotstein There are limited data on blastomycosis in solid organ transplant recipients with the subsequent development of the immune reconstitution inflammatory syndrome (IRIS). Herein we describe a case of pulmonary blastomycosis in a renal transplant recipient with the development of concomitant IRIS. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - March 2, 2018 Category: Biology Source Type: research
Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease
We report a case of tracheal, laryngeal and pulmonary mucormycosis in a patient receiving immunosuppressive medication for an autoinflammatory fever syndrome. Mucormycosis was confirmed by histopathology from tracheal specimens and molecular evidence of Lichtheimia. A surgical approach was not possible because of the multifocal disease pattern and the extent of tracheal involvement. The patient was successfully treated with liposomal amphotericin B followed by posaconazole maintenance therapy. After 9 months, recurrent pulmonary mucormycosis was suspected but emerged as organizing pneumonia without evidence of active funga...
Source: Medical Mycology Case Reports - March 2, 2018 Category: Biology Source Type: research
