Vascular pythiosis of carotid artery with meningitis and cerebral septic emboli: A case report and literature review
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Maria Nina Chitasombat, Porkaew Petchkum, Suthas Horsirimanont, Pattana Sornmayura, Ariya Chindamporn, Theerapong KrajaejunAbstractVascular Pythiosis caused by Pythium insiodiosum rarely involves carotid artery. A case of concealed ruptured pseudoaneurysm of the carotid artery with neck abscesses, and cerebral septic emboli is described. Patient presented with large pulsatile neck mass that failed to response to surgery, antifungals and immunotherapeutic vaccine. Residual unresectable disease leads to death in the patient. Pythiosis ...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Incidental findings of blastomycosis lung nodules in five asymptomatic patients
In this report we describe five sporadic cases of blastomycosis in asymptomatic patients. All of these cases were initially identified as incidental findings of lung nodules on CXR or CT. To our knowledge, these are the first detailed descriptions of asymptomatic blastomycosis, occurring as sporadic disease, in the literature. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

T2Candida® to guide antifungal and lengh of treatment of candidemia in a pediatric multivisceral transplant recipient
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Iker Falces-Romero, Emilio Cendejas-Bueno, María Laplaza-González, Luis Escosa-García, Cristina Schuffelmann-Gutiérrez, Belén Calderón-Llopis, Javier Pemán, Pedro de la Oliva, Julio García-RodríguezAbstractA case of 1-year- old male multivisceral transplant recipient with candidemia diagnosed by the T2Candida® test is presented. Optimal management of the candidemia complemented the treatment of the global clinical episode. Duration of treatment might be established much more precisely with the T2Candida® test than with blo...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research

Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Daiki Karigane, Masatoshi Sakurai, Emiko Matsuyama, Kentaro Ide, Sakiko Yamamoto-Takeuchi, Toyoko Inazumi, Sumiko KohashiAbstractWe encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis. Although itraconazole was ineffective in protecting against trichosporonosis, treatment was successful with voriconazole following liposomal amphotericin B. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Necrotizing fasciitis caused by Apophysomyces variabilis in an immunocompetent patient
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): José Y. Rodríguez, Soraya E. Morales-López, Gerson J. Rodríguez, Carlos A. Álvarez-Moreno, Walter Ocampo, Martha L. Cepeda, Miguel A. Mora-ValderramaAbstractMucormycosis caused by Apophysomyces variabilis is rarely reported in humans. A case of A. variabilis infection in an immunocompetent men after friction burns in a car accident is described. The infection presented as a rapidly progressive necrotizing infection of the skin and soft tissue, which required extensive surgical debridement and total colonic defunctioning colostomy ass...
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Dermatophyte infection caused by Nannizzia gypsea: A rare case report from Madagascar
We report a rare case of dermatophyte infection of the glabrous skin (Tinea corporis) caused by Nannizzia gypsea (formerly Microsporum gypseum). A 22-year-old Malagasy female who reported close contact reportedly with cats, presented a single round lesion with a peripheral, active, squamous and pruriginous inflammatory bead. Morphologic species identification was confirmed by sequencing the internal transcribed spacer (ITS) region of the genome. Specific treatment with oral loratadine and topical miconazole cream was effective. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Diagnosis and management of a fatal case of sepsis caused by Candida parapsilosis sensu stricto in a neonate with omphalocele
We present a fatal case of persistent neonatal candidemia by Candida parapsilosis following omphalocele, without other anomalies. Despite an encouraging initial prognosis, after surgical correction and closure of the abdominal wall the case became difficult to treat, as in addition to the exposure of the patient to multiple risk factors for candidemia, antifungal therapy apparently was not adequate. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Hemophagocytic lymphohistiocytosis (HLH) secondary to disseminated histoplasmosis in the setting of Acquired Immunodeficiency Syndrome (AIDS)
We present a case of a middle-aged male with AIDS and renal failure, who developed HLH secondary to disseminated histoplasmosis. Etoposide chemotherapy as recommended by the HLH 2004 Guidelines was deferred and treatment focused instead on anti-fungal therapy. Anti-retroviral therapy followed thereafter. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Mould meningitis associated with intravenous drug use
We present a rare case of mould meningitis, ventriculitis and subependymal nodules in an immunocompetent patient, having likely seeded the meninges and ventricular system through intravenous drug use. The causative mould remains undetermined. The case highlights the poor sensitivity of CSF culture and the need to consider surgical biopsy where there is diagnostic difficulty and fungal infection is being considered. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Acute paracoccidioidomycosis with duodenal and cutaneous involvement and obstructive jaundice
We report a case of PCM with duodenal and cutaneous involvement simulating cholangitis that was initially misdiagnosed as a lymphoproliferative disease. Clinicians should consider acute paracoccidioidomycosis in the differential diagnosis of jaundice and/or signs/symptoms of cholangitis developing in young patients from paracoccidioidomycosis endemic regions. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Case of Scedosporium aurantiacum infection detected in a subcutaneous abscess
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Makoto Kondo, Hiroyuki Goto, Keiichi YamanakaAbstractThis is the case report of a Scedosporium aurantiacum infection in a subcutaneous abscess. The patient had underlying diabetes and malignant lymphoma. Scedosporium species occur widely in nature and are increasingly recognized as pathologies under specific conditions, such as in immunocompromised hosts. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease
We report a case of tracheal, laryngeal and pulmonary mucormycosis in a patient receiving immunosuppressive medication for an autoinflammatory fever syndrome. Mucormycosis was confirmed by histopathology from tracheal specimens and molecular evidence of Lichtheimia.A surgical approach was not possible because of the multifocal disease pattern and the extent of tracheal involvement. The patient was successfully treated with liposomal amphotericin B followed by posaconazole maintenance therapy. After 9 months, recurrent pulmonary mucormycosis was suspected but emerged as organizing pneumonia without evidence of active fungal...
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Late presentation of Pneumocystis jirovecii pneumonia after renal transplant: A case report
We report a rare case of Pneumocystis jirovecii pneumonia in a renal transplant recipient only on maintenance immunosuppression eleven years after transplant without concomitant CMV infection or recent episodes of graft rejection. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Differential distribution patterns of Fonsecaea agents of chromoblastomycosis, exemplified by the first case due to F. monophora from Argentina
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Marcelo Label, Luciana C. Karayan, Sybren De Hoog, Javier Afeltra, Togo Bustamante, Roxana G. VitaleAbstractChromoblastomycosis is a mutilating infection of the skin and subcutaneous tissues caused by melanized fungi belonging to the order Chaetothyriales. Proven cases of the main agent, Fonsecaea pedrosoi are mainly limited to (sub)tropical, humid climates of Latin and Central America and the Caribbean. Fonsecaea monophora has a global distribution along the equator. Cases outside the (sub)tropics have thus far mostly been considered to ...
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research

Acute fulminant invasive pulmonary aspergillosis in an immunocompetent host: An autopsy case report
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Yuuki Ohara, Takahiko Ito, Makoto Ito, Kyoko Yamashita, Shinya ToyokuniAbstractA 62-year-old previously healthy male who was a welder/smoker/drinker was admitted to Kani Tono Hospital for severe hypoxemia (Day 0). Initial physical and radiological examinations suggested an acute exacerbation of chronic obstructive pulmonary disease. However, respiratory failure developed rapidly, and he died on Day + 4. Aspergillus fumigatus was identified after his death, and he was diagnosed with invasive pulmonary aspergillosis. The clinical and path...
Source: Medical Mycology Case Reports - July 5, 2018 Category: Biology Source Type: research