Isolation of Cryptococcus gattii VGIII from feline nasal injury
Publication date: Available online 12 September 2018Source: Medical Mycology Case ReportsAuthor(s): Peggy Vieille, Rodrigo Cruz, Paula León, Nicolás Cáceres, Gustavo GiusianoAbstractHereby we communicate the first autochthon isolation of Cryptococcus gattii VGIII in Chile, which was obtained from a nasal injury in a domestic cat in the Valparaíso region in Chile. The strain was identified using morphophysiological tests, MALDI-TOF, and URA5 gene PCR-RFLP analysis. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 13, 2018 Category: Biology Source Type: research
Intracatheter Antifungal Lock Leading to Detrimental Complications
We report two cases where antifungal lock were performed in PD patients presented with PD-related fungal infection that not only had no effect on abating the infection but also causing paradoxical outcomes. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 13, 2018 Category: Biology Source Type: research
Post-traumatic fatal disseminated Apophysomyces elegans infection
We describe a case of disseminated post-traumatic Apophysomyces elegans in an immunocompetent patient status-post soil inoculation. Fungi introduced at a deep arm laceration leads to neurovascular invasion and dissemination prior to amputation and systemic treatment. We specify strict post-traumatic wound surveillance protocol and roles of novel tissue tests to improve time to diagnosis and prognosis of frequently fatal post-traumatic Mucorales infections (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - September 7, 2018 Category: Biology Source Type: research
Fatal fulminant cryptococcemia complicating sarcoidosis: is it to be expected?
We describe a case of cryptococcemia that rapidly progressed toward fatality without apparent other sites of infection. We discuss on the importance of serum cryptococcal polysaccharide antigen testing for identifying at-risk patients who might benefit from timely diagnosis and treatment of cryptococcosis (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 17, 2018 Category: Biology Source Type: research
Successful treatment of C. auris shunt infection with intraventricular caspofungin
We describe here an adult with nosocomial CSF shunt infection due to multi drug resistant C. auris. Systemic therapy with echinocandin and flucytosine failed. Fortunately, administration of daily intraventricular caspofungin 10 mg for 10 days in conjunction with systemic voriconazole resulted in both clinical and microbiological cure. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 12, 2018 Category: Biology Source Type: research
Canine rhinitis caused by an uncommonly-diagnosed fungus, Scedosporium apiospermum
Publication date: Available online 8 August 2018Source: Medical Mycology Case ReportsAuthor(s): Christopher Smith, Lucy Woolford, Jessica Talbot, Ken C Lee, Paul CrockerAbstractA Golden Retriever cross was presented with a four week history of violent sneezing and licking at the nasal planum. Nasal mycosis was diagnosed and Aspergillus sp. presumed the causative agent, until culture, PCR and DNA sequencing showed that Scedosporium apiospermum, an uncommonly diagnosed, yet emerging, fungal pathogen, was the agent responsible. Debridement of the fungal plaques and systemic itraconazole therapy resulted in complete resolution...
Source: Medical Mycology Case Reports - August 8, 2018 Category: Biology Source Type: research
Aspergillus flavus endocarditis in an immunocompetent child. case report
We present an immunocompetent 7- year-old female with a history of multiple cardiac surgeries who developed fungal endocarditis due to Aspergillus flavus. The histology study showed liquefactive necrosis and septate hyphae of Aspergillus sp type. The clinical outcome was favorable and the ambulatory follow-up after 12 months showed no new complications. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 8, 2018 Category: Biology Source Type: research
Disseminated angioinvasive basidiobolomycosis with a favourable outcome
We report this case to remind physicians and surgeons to consider this diagnosis in patients from endemic area presenting with such conditions. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - August 8, 2018 Category: Biology Source Type: research
Kodamaea ohmeri fungemia in severe burn: case study and literature review
Publication date: Available online 20 July 2018Source: Medical Mycology Case ReportsAuthor(s): Ayaka Tashiro, Takahito Nei, Ryoji Sugimoto, Akiko Watanabe, Jun Hagiwara, Toru Takiguchi, Hiroyuki Yokota, Katsuhiko KameiAbstractKodamaea ohmeri is a relatively rare yeast isolated form clinical specimens, and it is known to be a causative fungus of severe invasive infectious diseases in immunocompromised hosts. Herein, we describe fungemia due to K. ohmeri in a patient with a severe extended burn. The isolate was obtained from not only blood specimens but also skin lesions. We should be aware of risk for fungemia including K. ...
Source: Medical Mycology Case Reports - July 20, 2018 Category: Biology Source Type: research
Cutaneotrichosporon (Cryptococcus) cyanovorans, a basidiomycetous yeast, isolated from the airways of cystic fibrosis patients
Publication date: Available online 18 July 2018Source: Medical Mycology Case ReportsAuthor(s): Tjomme van der Bruggen, Anna Kolecka, Bart Theelen, Johanna M. Kwakkel-van Erp, Bert Arets, Teun BoekhoutAbstractCystic fibrosis (CF) patients are colonized with a multitude of bacteria and fungi. From respiratory samples of two CF patients in our institute, a difficult to identify yeast was isolated repeatedly. This yeast was eventually identified as Cutaneotrichosporon (Cryptococcus) cyanovorans by internal transcribed spacer (ITS) and ribosomal large subunit (LSU) sequencing. C. cyanovorans is a basidiomycetous yeast originall...
Source: Medical Mycology Case Reports - July 19, 2018 Category: Biology Source Type: research
Late-onset isavuconazole-induced liver injury
We report a case of late-onset DILI occurring after 11 months of isavuconazole therapy in a 55-year old man of Angolan descent on long-term antifungal therapy for the management of chronic pulmonary aspergillosis complicating previously treated pulmonary tuberculosis. The DILI could be described as idiosyncratic as it was not associated with high isavuconazole serum levels and his liver function tests returned to normal following treatment discontinuation. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 19, 2018 Category: Biology Source Type: research
Aspergillus Hepatic Artery Thrombosis in Liver Transplantation
We present the first cirrhotic patient who underwent liver transplantation (LT) and presented a hepatic artery thrombosis of the graft due to Aspergillus fumigatus, within the first month of LT. This culminated in graft loss, re-transplant with multiple biliary and infectious complications. To our knowledge, this is a case report of an early hepatic artery thrombosis due to Aspergillus fumigatus in an infection-free patient. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 19, 2018 Category: Biology Source Type: research
Donor-derived invasive aspergillosis after kidney transplant
We report 2 cases of kidney transplant recipients who acquired aspergillosis from a single donor. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 18, 2018 Category: Biology Source Type: research
Bilateral Candida keratitis in an HIV patient with asymptomatic genitourinary Candidiasis in Uganda
Publication date: Available online 17 July 2018Source: Medical Mycology Case ReportsAuthor(s): Simon Arunga, Teddy Kwaga, Astrid Leck, Victor H Hu, Matthew J BurtonAbstractA 35-year-old male presented with Candida keratitis in the left eye. He was HIV positive with a CD4 of 352 cells/µL. The eye quickly deteriorated, despite intensive antifungal treatment and was eviscerated. Five months later, he re-presented with Candida keratitis in his right eye. A focal source of Candida infection was suspected and a urine culture identified Candida spp, despite being asymptomatic for genitourinary candidiasis. He was subsequently tr...
Source: Medical Mycology Case Reports - July 17, 2018 Category: Biology Source Type: research
Disseminated Cryptococcosis in a HIV-Negative Patient: Case Report of a Newly Diagnosed Hypertensive Adult Presenting with Hemiparesis
We report a case of disseminated cryptococcosis in a 42-year old immunocompetent female. Prior to admission at Bugando Medical Centre, the patient was attended at three hospitals for hypertension and clinically diagnosed malaria. Following diagnosis of disseminated Cryptococcus at our center, she was successfully treated with fluconazole but remained with visual loss. Blood cultures should be considered in the management of any adult presenting with fever to enable early detection of the least expected differentials like in this case. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 13, 2018 Category: Biology Source Type: research
