Triadelphia pulvinata: A rare invasive fungal infection in a diabetic patient
We report a case of Triadelphia pulvinata, a rare dematiaceous fungi causing invasive fungal infection in a 68 year old diabetic Iraqi female. The diagnosis was made by combining the phenotypic findings and genome sequencing. There are only 4 case reports in literature and this is probably the first from India which was treated by Liposomal Amphotericin B. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Long term survival of a dog with disseminated Aspergillus deflectus infection without definitive treatment
Publication date: Available online 10 July 2018Source: Medical Mycology Case ReportsAuthor(s): Peter F. Bennett, Jessica J. Talbot, Patricia Martin, Sarah E Kidd, Mariano Makara, Vanessa R. BarrsAbstractCanine disseminated fungal infection by Aspergillus species carries a guarded to grave prognosis as they often rapidly progress and are refractory to treatment with many euthanased soon after diagnosis. This case report describes a 2.5 year old female spayed German Shepherd Dog diagnosed with disseminated Aspergillus deflectus infection for which definitive treatment was declined by the owners. With only palliative manageme...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Successful treatment of breakthrough disseminated Trichosporon asahii fungemia in a patient with acute myeloid leukemia receiving itraconazole prophylaxis
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Daiki Karigane, Masatoshi Sakurai, Emiko Matsuyama, Kentaro Ide, Sakiko Yamamoto-Takeuchi, Toyoko Inazumi, Sumiko KohashiAbstractWe encountered a case of a 73-year-old man with acute myeloid leukemia who developed Trichosporon asahii systemic infection while on itraconazole prophylaxis during severe neutropenia. Cryptococcal antigen was useful for diagnosis. Although itraconazole was ineffective in protecting against trichosporonosis, treatment was successful with voriconazole following liposomal amphotericin B. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Necrotizing fasciitis caused by Apophysomyces variabilis in an immunocompetent patient
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): José Y. Rodríguez, Soraya E. Morales-López, Gerson J. Rodríguez, Carlos A. Álvarez-Moreno, Walter Ocampo, Martha L. Cepeda, Miguel A. Mora-ValderramaAbstractMucormycosis caused by Apophysomyces variabilis is rarely reported in humans. A case of A. variabilis infection in an immunocompetent men after friction burns in a car accident is described. The infection presented as a rapidly progressive necrotizing infection of the skin and soft tissue, which required extensive surgical debridement and total colonic defunctioning colostomy ass...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Dermatophyte infection caused by Nannizzia gypsea: A rare case report from Madagascar
We report a rare case of dermatophyte infection of the glabrous skin (Tinea corporis) caused by Nannizzia gypsea (formerly Microsporum gypseum). A 22-year-old Malagasy female who reported close contact reportedly with cats, presented a single round lesion with a peripheral, active, squamous and pruriginous inflammatory bead. Morphologic species identification was confirmed by sequencing the internal transcribed spacer (ITS) region of the genome. Specific treatment with oral loratadine and topical miconazole cream was effective. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Diagnosis and management of a fatal case of sepsis caused by Candida parapsilosis sensu stricto in a neonate with omphalocele
We present a fatal case of persistent neonatal candidemia by Candida parapsilosis following omphalocele, without other anomalies. Despite an encouraging initial prognosis, after surgical correction and closure of the abdominal wall the case became difficult to treat, as in addition to the exposure of the patient to multiple risk factors for candidemia, antifungal therapy apparently was not adequate. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Hemophagocytic lymphohistiocytosis (HLH) secondary to disseminated histoplasmosis in the setting of Acquired Immunodeficiency Syndrome (AIDS)
We present a case of a middle-aged male with AIDS and renal failure, who developed HLH secondary to disseminated histoplasmosis. Etoposide chemotherapy as recommended by the HLH 2004 Guidelines was deferred and treatment focused instead on anti-fungal therapy. Anti-retroviral therapy followed thereafter. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Mould meningitis associated with intravenous drug use
We present a rare case of mould meningitis, ventriculitis and subependymal nodules in an immunocompetent patient, having likely seeded the meninges and ventricular system through intravenous drug use. The causative mould remains undetermined. The case highlights the poor sensitivity of CSF culture and the need to consider surgical biopsy where there is diagnostic difficulty and fungal infection is being considered. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Acute paracoccidioidomycosis with duodenal and cutaneous involvement and obstructive jaundice
We report a case of PCM with duodenal and cutaneous involvement simulating cholangitis that was initially misdiagnosed as a lymphoproliferative disease. Clinicians should consider acute paracoccidioidomycosis in the differential diagnosis of jaundice and/or signs/symptoms of cholangitis developing in young patients from paracoccidioidomycosis endemic regions. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Case of Scedosporium aurantiacum infection detected in a subcutaneous abscess
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Makoto Kondo, Hiroyuki Goto, Keiichi YamanakaAbstractThis is the case report of a Scedosporium aurantiacum infection in a subcutaneous abscess. The patient had underlying diabetes and malignant lymphoma. Scedosporium species occur widely in nature and are increasingly recognized as pathologies under specific conditions, such as in immunocompromised hosts. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Tracheal, laryngeal and pulmonary mucormycosis followed by organizing pneumonia in a patient with Adult Onset Still's Disease
We report a case of tracheal, laryngeal and pulmonary mucormycosis in a patient receiving immunosuppressive medication for an autoinflammatory fever syndrome. Mucormycosis was confirmed by histopathology from tracheal specimens and molecular evidence of Lichtheimia.A surgical approach was not possible because of the multifocal disease pattern and the extent of tracheal involvement. The patient was successfully treated with liposomal amphotericin B followed by posaconazole maintenance therapy. After 9 months, recurrent pulmonary mucormycosis was suspected but emerged as organizing pneumonia without evidence of active fungal...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Late presentation of Pneumocystis jirovecii pneumonia after renal transplant: A case report
We report a rare case of Pneumocystis jirovecii pneumonia in a renal transplant recipient only on maintenance immunosuppression eleven years after transplant without concomitant CMV infection or recent episodes of graft rejection. (Source: Medical Mycology Case Reports)
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Differential distribution patterns of Fonsecaea agents of chromoblastomycosis, exemplified by the first case due to F. monophora from Argentina
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Marcelo Label, Luciana C. Karayan, Sybren De Hoog, Javier Afeltra, Togo Bustamante, Roxana G. VitaleAbstractChromoblastomycosis is a mutilating infection of the skin and subcutaneous tissues caused by melanized fungi belonging to the order Chaetothyriales. Proven cases of the main agent, Fonsecaea pedrosoi are mainly limited to (sub)tropical, humid climates of Latin and Central America and the Caribbean. Fonsecaea monophora has a global distribution along the equator. Cases outside the (sub)tropics have thus far mostly been considered to ...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Acute fulminant invasive pulmonary aspergillosis in an immunocompetent host: An autopsy case report
Publication date: June 2018Source: Medical Mycology Case Reports, Volume 20Author(s): Yuuki Ohara, Takahiko Ito, Makoto Ito, Kyoko Yamashita, Shinya ToyokuniAbstractA 62-year-old previously healthy male who was a welder/smoker/drinker was admitted to Kani Tono Hospital for severe hypoxemia (Day 0). Initial physical and radiological examinations suggested an acute exacerbation of chronic obstructive pulmonary disease. However, respiratory failure developed rapidly, and he died on Day + 4. Aspergillus fumigatus was identified after his death, and he was diagnosed with invasive pulmonary aspergillosis. The clinical and path...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
Severe acute respiratory distress syndrome in a liver transplant patient
Publication date: September 2018Source: Medical Mycology Case Reports, Volume 21Author(s): Nicholas M. Moore., Laurie A. ProiaAbstractThis case report presents a 46-year old man with a failed liver transplant who presented with malaise and dyspnea. Imaging studies revealed diffuse reticulonodular infiltrates and innumerable miliary nodules and a left upper lobe consolidative mass. Examination of bronchoalveolar lavage fluid demonstrated yeast cells with broad-based budding. He was diagnosed with pulmonary blastomycosis and started therapy with liposomal amphotericin. In spite of therapy, he clinically worsened, developing ...
Source: Medical Mycology Case Reports - July 11, 2018 Category: Biology Source Type: research
