Numerical optimization of cell colonization modelling inside scaffold for perfusion bioreactor: A multiscale model
Michaelis-Menten constant () (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - May 10, 2018 Category: Biomedical Engineering Authors: T-K. Nguyen, O. Carpentier, F. Monchau, F. Chai, J.C. Hornez, P. Hivart Source Type: research

Validated computational framework for efficient systematic evaluation of osteoporotic fracture fixation in the proximal humerus
Proximal humerus fractures represent the third most frequent osteoporosis-related injury in the elderly with expected increasing incidence due to the ageing population and prevalence of osteoporosis [1 –4]. Management of unstable fractures requires surgical treatment to achieve and maintain anatomical reduction, enable early functional recovery and ensure rapid healing. Joint-preserving treatment options include intramedullary nailing and plating. The introduction of locking plates revolutionize d fracture treatment at this anatomical site [5,6]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - May 1, 2018 Category: Biomedical Engineering Authors: Peter Varga, Jason A. Inzana, Boyko Gueorguiev, Norbert P. S üdkamp, Markus Windolf Source Type: research

Air conditioning analysis among human nasal passages with anterior anatomical variations
Nasal breathing is vital for most species, and one of the major functions of the nasal cavity is the conditioning (regulating the temperature and humidity) of the inspired environmental air to near alveolar conditions for the lungs. The nasal passages narrow at the nasal valve and widen as they reach the middle region, which is composed of wing-like structures (nasal turbinate) that emerge from the lateral walls. These slit-like structures of the nasal cavity provide exchange of heat and moisture as it assures close contact between the inhaled air and mucous membrane, and the arteriovenous anastomoses facilitates the heat ...
Source: Medical Engineering and Physics - April 27, 2018 Category: Biomedical Engineering Authors: Jiawei Ma, Jingliang Dong, Yidan Shang, Kiao Inthavong, Jiyuan Tu, Dennis O. Frank-Ito Source Type: research

Evaluation of matrix factorisation approaches for muscle synergy extraction
“How does the central nervous system (CNS) control body movements and posture?” This question has been discussed for over a century with no conclusive answer. The coordination of muscles and joints that accompanies movement requires multiple degree of freedoms (DoFs). This results a high level o f complexity and dimensionality [1]. A possible explanation to this problem considers the notion that the CNS constructs a movement as a combination of small groups of muscles (synergies) that act in harmony with each other, thus reducing the dimensionality of the problem. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 24, 2018 Category: Biomedical Engineering Authors: Ahmed Ebied, Eli Kinney-Lang, Loukianos Spyrou, Javier Escudero Source Type: research

Electrohysterographic characterization of the uterine myoelectrical response to labor induction drugs
Labor induction is now a daily obstetric routine and is performed in an ever-increasing number of cases. It is indicated when the risk to mother and fetus of continuing the pregnancy outweighs that of terminating it. The goal is to achieve vaginal delivery by stimulating uterine contractions before the spontaneous onset of labor by promoting uterine contractions. Its use has increased significantly in recent years, from 9.0% of all births in 1989 to 23% in 2012 in the United States [1]. Labor induction can last for many hours (approximately 17 –20 [2]), sometimes more than 36 h, and in most cases does not ensure vaginal...
Source: Medical Engineering and Physics - April 23, 2018 Category: Biomedical Engineering Authors: Carlos Benalcazar-Parra, Yiyao Ye-Lin, Javier Garcia-Casado, Rogelio Monfort-Orti, Jose Alberola-Rubio, Alfredo Perales, Gema Prats-Boluda Source Type: research

Separation of electrocardiographic from electromyographic signals using dynamic filtration
Electromyographic (EMG) signals of surface placed muscles are often used for: estimation of the force developed by a muscle [1]; conclusions about the role of different types of muscle motor units in different motor tasks [2,3]; analysis of changes in muscle functioning caused by different neuro-muscular diseases [4,5]; control of different technical devices as ortheses [6,7], exoskeletons, prosthesis, etc. It is clearly visible that electrocardiographic (ECG) signals superimpose the EMG signal when some of the investigated muscles are trunk muscles and especially for those ones placed on the left. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 23, 2018 Category: Biomedical Engineering Authors: Ivaylo Christov, Rositsa Raikova, Silvija Angelova Source Type: research

Electrohysterographic characterization of the uterine myoelectrical response to labor induction drugs
Labor induction is now a daily obstetric routine and is performed in an ever-increasing number of cases. It is indicated when the risk to mother and fetus of continuing the pregnancy outweighs that of terminating it. The goal is to achieve vaginal delivery by stimulating uterine contractions before the spontaneous onset of labor by promoting uterine contractions. Its use has increased significantly in recent years, from 9.0% of all births in 1989 to 23% in 2012 in the United States [1]. Labor induction can last for many hours (approximately 17 –20 [2]), sometimes more than 36 h, and in most cases does not ensure vaginal...
Source: Medical Engineering and Physics - April 23, 2018 Category: Biomedical Engineering Authors: Carlos Benalcazar-Parra, Yiyao Ye-Lin, Javier Garcia-Casado, Rogelio Monfort-Orti, Jose Alberola-Rubio, Alfredo Perales, Gema Prats-Boluda Source Type: research

Separation of electrocardiographic from electromyographic signals using dynamic filtration
Electromyographic (EMG) signals of surface placed muscles are often used for: estimation of the force developed by a muscle [1]; conclusions about the role of different types of muscle motor units in different motor tasks [2,3]; analysis of changes in muscle functioning caused by different neuro-muscular diseases [4,5]; control of different technical devices as ortheses [6,7], exoskeletons, prosthesis, etc. It is clearly visible that electrocardiographic (ECG) signals superimpose the EMG signal when some of the investigated muscles are trunk muscles and especially for those ones placed on the left. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 23, 2018 Category: Biomedical Engineering Authors: Ivaylo Christov, Rositsa Raikova, Silvija Angelova Source Type: research

Detection of daily postures and walking modalities using a single chest-mounted tri-axial accelerometer
Quantitative assessment of physical activities during daily life plays a significant role in evaluating the functional ability and the level of activity in healthy individuals and patients suffering from obesity, recurrent falling, Parkinson's disease, and back pain [1 –5]. In recent years, wearable inertial sensors with lightweight, long battery life, and large memory have become increasingly popular for ambulatory human motion analysis [6,7]. Najafi et al. [4,8] adopted the trunk inclination angle, obtained from the integration of the angular velocity and disc rete wavelet transform (DWT), to detect postural transition...
Source: Medical Engineering and Physics - April 21, 2018 Category: Biomedical Engineering Authors: Milad Nazarahari, Hossein Rouhani Tags: Technical note Source Type: research

Establishing the relationship between loading parameters and bone adaptation
Bone loss is a serious health issue which occurs due to metabolic bone disorders such as osteoporosis, and bone or muscle disuse. In vivo studies observed bone loss in postmenopausal women, bedridden patients, physically challenged individuals, and in astronauts under microgravity environment [1]. In fact, astronauts experience trabecular bone loss of 0.4% to 23.4% during 6 months spaceflight [2]. Bone loss reduces weight bearing strength of long bones which also increases the possibility of frequent bone fractures [3]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 20, 2018 Category: Biomedical Engineering Authors: Abhishek Kumar Tiwari, Navin Kumar Source Type: research

Importance of a moderate plate-to-bone distance for the functioning of the far cortical locking system
The main objective of any bone fixation device is to achieve fracture union. Conventional methods that use dynamic compression plates rely on a very rigid construct to allow direct bone healing. In recent decades, the internal fixation of long bone fractures has developed, and now involves biological, rather than mechanical methods; thus, more flexible constructs are favored to induce secondary bone healing by callus formation [1 –3]. With the introduction of locking compression plates as a fixed-angle screw locked mechanism, this technique avoids the need for precise reduction and plate compression against the underlyin...
Source: Medical Engineering and Physics - April 20, 2018 Category: Biomedical Engineering Authors: Jesse Chieh-Szu Yang, Kang-Ping Lin, Hung-Wen Wei, Wen-Chuan Chen, Chao-Ching Chiang, Ming-Chau Chang, Cheng-Lun Tsai, Kun-Jhih Lin Tags: Technical note Source Type: research

Three-dimensional printing as a technology supporting the treatment of lower limb deformity and shortening with the Ilizarov method
Orthopedists should consider differences between the expected and actual lengthening and axial correction in planning treatment with the Ilizarov method. Three-dimensional printing is a useful technology that can be used to support treatment with the Ilizarov method. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 20, 2018 Category: Biomedical Engineering Authors: Piotr Morasiewicz, Karolina Burzy ńska, Wiktor Orzechowski, Szymon Łukasz Dragan, Szymon Feliks Dragan, Jarosław Filipiak Tags: Technical note Source Type: research

Establishing the relationship between loading parameters and bone adaptation
Bone loss is a serious health issue which occurs due to metabolic bone disorders such as osteoporosis, and bone or muscle disuse. In vivo studies observed bone loss in postmenopausal women, bedridden patients, physically challenged individuals, and in astronauts under microgravity environment [1]. In fact, astronauts experience trabecular bone loss of 0.4% to 23.4% during 6 months spaceflight [2]. Bone loss reduces weight bearing strength of long bones which also increases the possibility of frequent bone fractures [3]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - April 20, 2018 Category: Biomedical Engineering Authors: Abhishek Kumar Tiwari, Navin Kumar Source Type: research