Sharif-Human movement instrumentation system (SHARIF-HMIS): Development and validation
Measuring human movement and activity levels has become increasingly important for several disciplines —notably biomedical engineering and healthcare (e.g., in designing a rehabilitation protocol for patients). In general, the current systems for obtaining such data fall under two broad umbrellas: non-wearable and wearable systems. Non-wearable systems are almost exclusively used for indoor applica tions as they often must capture data through wired connections and may require ongoing adjustments. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - September 1, 2018 Category: Biomedical Engineering Authors: Mohammad Iman Mokhlespour Esfahani, Ali Akbari, Omid Zobeiri, Ehsan Rashedi, Mohamad Parnianpour Tags: Technical note Source Type: research

3D Printed composite for simulating thermal and mechanical responses of the cortical bone in orthopaedic surgery
Orthopaedic surgery involves the machining of bones for screw placement and fracture fixation. These procedures are critical to surgical outcomes as they often accompany the risk of inadvertent damage to the adjacent anatomical structures thermally or mechanically. In addition, improper screw and plate placement can result in failure of implants and bone fracture. Development and refinement of surgical skill are, therefore, important and often time-consuming during the training curriculum of novice surgeons. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - September 1, 2018 Category: Biomedical Engineering Authors: Bruce L. Tai, Yi-Tang Kao, Nolan Payne, Yihao Zheng, Lei Chen, Albert J. Shih Source Type: research

Model development and comparison of low hemorrhage-risk endoluminal patch thrombolytic treatment for ischemic stroke
A thrombus blocking flow in a blood vessel deprives the brain cells of oxygen resulting in ischemic stroke and paralysis [1]. Thrombolysis treatment can be used to unblock the vessel [2]. A high dose of thrombolytic agents (urokinase plasminogen activator (uPA) or tissue plasminogen activator (tPA)) is administered to dissolve the blocking thrombus in eligible patients who are within 4.5  h from stroke onset [3,4]. Typically, 10,000–60,000 IU/kg ( (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 31, 2018 Category: Biomedical Engineering Authors: Zhen Qin, Francesco Ciucci, Chi Hang Chon, John C.K. Kwok, David C.C. Lam Source Type: research

Motion analysis of the cervical spine during extension and flexion: Reliability of the vertebral marking procedure
Real-time radiographic motion assessment of osseous structures is replacing the old gold standards and uncovers new knowledge and understanding of the natural flexion and extension spinal motion, previously not accessible from static radiographic images [1 –3]. Analysis techniques involving videofluoroscopy have demonstrated good results in the mid-, and lower cervical spine [1,2,4–8]. However, current understanding of the natural spinal motion is still limited, since very few studies documented a real-time analysis of unrestricted cervical motion [1,9], even though biomechanical assessments of cervical joint motions a...
Source: Medical Engineering and Physics - August 30, 2018 Category: Biomedical Engineering Authors: Maciej Plocharski, Rene Lindstroem, Cassandra Frydendal Lindstroem, Lasse Riis Østergaard Tags: Technical note Source Type: research

An intelligent system for image-based rating of corrosion severity at stem taper of retrieved hip replacement implants
Adverse Local Tissue Reactions (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 23, 2018 Category: Biomedical Engineering Authors: Roohollah Milimonfared, Reza H. Oskouei, Mark Taylor, Lucian B. Solomon Source Type: research

A mixed linear modelling characterisation of gender and speed related changes in spatiotemporal and kinematic characteristics of gait across a wide speed range in healthy adults
It is well known that changes in walking speed change spatiotemporal characteristics and the joint angles used [1 –6]. The exploration of the relationship between characteristics of gait and speed has been accomplished using various methods. For example asking people to walk at ‘slow’, ‘normal’ and ‘fast’ speeds has been used to derive parameters related to a normal speed and a speed lower and hig her than this normal speed [2–4,7–9]. This allows the comparison of the outcomes between these groups, providing evidence that there are changes with speed. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 18, 2018 Category: Biomedical Engineering Authors: Ben Stansfield, Katrina Hawkins, Sarah Adams, Haseel Bhatt Source Type: research

Experimentally derived viscoelastic properties of human skin and muscle in vitro
Human skin consists of several layers that exhibit nonlinear, nonhomogeneous, viscoelastic, and time-dependent behavior [1]. It is very difficult to identify its mechanical properties precisely. Basic mechanical properties such as Young's modulus and the loss factor are generally employed to simulate the mechanical behavior of human skin. They have been investigated for a long time because they are related to several important applications such as surgical simulation, cosmetics, and impact biomechanics. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 18, 2018 Category: Biomedical Engineering Authors: Moon Jeong Kang, Bo-seung Kim, Sejin Hwang, Hong Hee Yoo Source Type: research

Comparative study of actuation systems for portable upper limb exoskeletons
Stroke is the fourth leading cause of death in the UK. At present, there are over 1.2 million stroke survivors in the UK [1]. According to the Stroke Association, the way of recovery of stroke patients depends on the process of rehabilitation which includes all orthopedic lessons at different phases after stroke [2]. Existing manual therapy has several drawbacks such as the cost of therapy, physical issues from physiotherapy and lack of sufficient number of physiotherapists. Long-term involvement of rehabilitation therapists imposes a huge cost burden. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 17, 2018 Category: Biomedical Engineering Authors: Soumya K Manna, Venketesh N. Dubey Source Type: research

The effect of plaque eccentricity on blood hemodynamics and drug release in a stented artery
Atherosclerosis is one of the most serious and common forms of cardiovascular disease which arises due to the accumulation of fatty deposits, cholesterol, and calcified materials in the arterial wall [1]. As a consequence of this accumulation, the lumen is occluded and the problem gets worse with age [2]. Different treatments, from invasive techniques such as coronary artery bypass grafting to safer and less invasive techniques like percutaneous coronary intervention (PCI), have been developed to prevent lumen occlusion [3]. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 12, 2018 Category: Biomedical Engineering Authors: Jos é A. Ferreira, Lino Gonçalves, Jahed Naghipoor, Paula de Oliveira, Timon Rabczuk Source Type: research

An interpolation technique to enable accurate three-dimensional joint kinematic analyses using asynchronous biplane fluoroscopy
The notion of registering 3D bone volumes to fluoroscopic images in order to quantify 3D joint kinematics in vivo has been studied for several decades [1]. Biplane fluoroscopy is a highly accurate way to measure 3D joint kinematics, using two common techniques of bead tracking (fluoroscopic radiostereometric analysis (RSA)) or 2D-3D model-based registration [2 –13]. When imaging a moving object, the accuracy of the estimated 3D bone pose using these techniques is very sensitive to the synchronicity of image acquisition between the two planes. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 8, 2018 Category: Biomedical Engineering Authors: Mohsen Akbari-Shandiz, Joseph D. Mozingo, David R. Holmes III, Kristin D. Zhao Tags: Technical note Source Type: research

A spatial filtering approach to environmental emotion perception based on electroencephalography
Studies have shown that psychological problems have increased significantly among Chinese adolescents in recent years [1,2]. According to conservative estimates, 30 million children and adolescents have different psychological problems [1], and 16.0 –25.4% of undergraduate students have mental disorders such as anxiety, neurotic behaviors, neurasthenia, and depression [3]. Moreover, these psychological problems have a trend to increase in prevalence at present. The World Health Organization predicted that the number of adolescents with neurop sychological problems will increase worldwide by more than 50% by the year 2020...
Source: Medical Engineering and Physics - August 8, 2018 Category: Biomedical Engineering Authors: Yuanyuan Su, Peng Chen, Xueying Liu, Wenchao Li, Zhao Lv Source Type: research

Validity of the Microsoft Kinect ™ in assessing spatiotemporal and lower extremity kinematics during stair ascent and descent in healthy young individuals
Stair negotiation is a more challenging activity than level walking [1-3], since in order to continue forward progress and establish proper foot displacement during each step, the body center of mass (COM) must be lifted during ascent and lowered during descent with each change in single limb support [3]. Additionally, stair negotiation requires individuals to move their body weight against gravity and negotiate each step, while maintaining balance and considering safety in order to reduce fall probability. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 8, 2018 Category: Biomedical Engineering Authors: Jeonghoon Oh, Christopher Kuenze, Marco Jacopetti, Joseph F. Signorile, Moataz Eltoukhy Source Type: research

The influence of bileaflet prosthetic aortic valve orientation on the blood flow patterns in the ascending aorta
The interplay with the blood flow and the heart valves, which provide unidirectional blood flow through the heart, is complicated since it involves flow pulsatility and complex, deformable geometries of both the valve and the aorta [1]. Malfunctions of the heart valves can affect the hemodynamics of the whole circulatory system [2,3] and these abnormalities can either be congenital or arise from abnormalities in hemodynamic behavior. Dysfunctional heart valves can usually be replaced with prosthetic heart valves, which, depending on the design and quality of insertion, offer variable hemodynamic performance and may be asso...
Source: Medical Engineering and Physics - August 8, 2018 Category: Biomedical Engineering Authors: Utku G ülan, Markus Holzner Source Type: research

Estimating regions of interest on the distal femur
femoral anterior condyle (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 7, 2018 Category: Biomedical Engineering Authors: Johan van der Merwe, Dawie J. van den Heever, Pieter J. Erasmus Source Type: research

Enabling portable multiple-line refreshable Braille displays with electroactive elastomers
The world's roughly 314 million blind and visually impaired people are largely excluded from today's digital revolution in information and communication technologies. Indeed, displays of computers, portable devices, touch screens and so forth are conceived to bring text and images via the sense of sight. (Source: Medical Engineering and Physics)
Source: Medical Engineering and Physics - August 6, 2018 Category: Biomedical Engineering Authors: Gabriele Frediani, James Busfield, Federico Carpi Source Type: research