Diagnosis of Anaphylactic death in forensics: review and future perspectives
Anaphylaxis is a type I hypersensitivity reaction which clinical symptoms can be mild to severe. It can cause death within few minutes due to cardiovascular collapse (anaphylactic shock), with symptoms like paleness, loss of consciousness, shallow breathing and frequent insensitivity to external stimuli, imperceptible pulse and severe hypotension, as well as angioedema, airway obstruction due to laryngeal oedema. In other occasions, it is presented with more subdued symptoms like nausea, vomiting, giant hives, asthma and wheezing. (Source: Legal Medicine)
Source: Legal Medicine - August 17, 2016 Category: Forensic Medicine Authors: Rossana Cecchi Source Type: research
Next-generation sequencing analysis of off-ladder alleles due to migration shift caused by sequence variation at D12S391 locus
Short tandem repeat (STR) analysis is widely used for population genetics, kinship analysis, and forensic examinations [1]. In STR analysis, length polymorphisms at target loci are usually amplified in a multiplex polymerase chain reaction (PCR) and detected by capillary electrophoresis (CE) under denaturing conditions. It was reported that some STR loci have sequence variation in the repeat region and have alleles of the same length but with different internal sequences (now called isoalleles) [2]. (Source: Legal Medicine)
Source: Legal Medicine - August 11, 2016 Category: Forensic Medicine Authors: Koji Fujii, Haruhiko Watahiki, Yusuke Mita, Yasuki Iwashima, Hajime Miyaguchi, Tetsushi Kitayama, Hiroaki Nakahara, Natsuko Mizuno, Kazumasa Sekiguchi Source Type: research
Variations of midfacial soft-tissue thickness in subjects aged between 6 and 18years for the reconstruction of the profile: A study on an Italian sample
Forensic facial reconstruction is a technique for reproducing facial features from a cranium and aims at providing a visual example of biological data (sex, age, ancestry) obtained from the skeletal remains by anthropological methods. Several techniques actually exist, both manual and computer-aided [1,2], but they are all based on the anatomical and functional relationships between the bone and the skin surface. Facial approximation [3] has shown in the last years an increase in importance in forensic sciences, because it allows the operators to create an image able to “capture” public attention towards the case. (Source: Legal Medicine)
Source: Legal Medicine - August 9, 2016 Category: Forensic Medicine Authors: Daniele Gibelli, Federica Collini, Davide Porta, Matteo Zago, Claudia Dolci, Cristina Cattaneo, Chiarella Sforza Tags: Short Communication Source Type: research
Evaluation of Y chromosomal SNP haplogrouping in the HID-Ion AmpliSeq ™ Identity Panel
Y chromosome exhibits extensive divergence, which serves in various fields such as anthropology and crime scene investigations. In forensic genetics, multiplex systems composed of Y chromosomal short tandem repeats (STR) have been applied for personal identification in sexual assault and other cases. In contrast to STR markers with high mutation rates [1,2], stable single nucleotide polymorphism (SNP) markers are more suitable for phylogenetic analysis. The haplogroup of Y chromosomal SNP combination is a valuable marker for examination of ancestral lineage and ethical divergence. (Source: Legal Medicine)
Source: Legal Medicine - August 9, 2016 Category: Forensic Medicine Authors: Eriko Ochiai, Kiyoshi Minaguchi, Phrabhakaran Nambiar, Yu Kakimoto, Fumiko Satoh, Masato Nakatome, Keiko Miyashita, Motoki Osawa Tags: Short Communication Source Type: research
DNA profile of dog feces as evidence to solve a homicide
Non-human DNA analysis in forensic science has seen growth in recent years. Applications range from investigations of crimes of humans to cruelty and poaching in animal/wildlife species, where DNA evidence from animals, plants, bacteria and viruses has been used in criminal investigations [1]. (Source: Legal Medicine)
Source: Legal Medicine - August 9, 2016 Category: Forensic Medicine Authors: L.S. Barrientos, J.A. Crespi, A. Fameli, D.M. Posik, H. Morales, P. Peral Garc ía, G. Giovambattista Source Type: research
