Association between an indel polymorphism in the 3 ′UTR of COL1A2 and the risk of sudden cardiac death in Chinese populations
Sudden cardiac death (SCD) describes the unexpected natural death from a cardiac cause within a short time period, generally (Source: Legal Medicine)
Source: Legal Medicine - July 18, 2017 Category: Forensic Medicine Authors: Zhixia Yin, Yadong Guo, Jianhua Zhang, Qing Zhang, Lijuan Li, Shouyu Wang, Chaoqun Wang, Yan He, Shaohua Zhu, Chengtao Li, Suhua Zhang, Lagabaiyila Zha, Jifeng Cai, Bin Luo, Yuzhen Gao Source Type: research
Association between an indel polymorphism in the 3'UTR of COL1A2 and the risk of sudden cardiac death in Chinese populations
Sudden cardiac death (SCD) describes the unexpected natural death from a cardiac cause within a short time period, generally (Source: Legal Medicine)
Source: Legal Medicine - July 18, 2017 Category: Forensic Medicine Authors: Zhixia Yin, Yadong Guo, Jianhua Zhang, Qing Zhang, Lijuan Li, Shouyu Wang, Chaoqun Wang, Yan He, Shaohua Zhu, Chengtao Li, Suhua Zhang, Lagabaiyila Zha, Jifeng Cai, Bin Luo, Yuzhen Gao Source Type: research
Early time-related course of image findings in postmortem MRI: Typical Findings and observer agreement in a porcine model
Postmortem cross-sectional imaging such as computed tomography (CT) and magnetic resonance imaging (MRI) have emerged as potential diagnostic alternatives to conventional autopsy [1] or serve as adjunct to give the opportunity to make a reinforcement of conventional examinations. Postmortem MRI reveals better soft-tissue contrast than postmortem CT and offers excellent anatomical detail to visualize pathologies at the expense of higher costs and longer examination times compared to postmortem CT [2]. (Source: Legal Medicine)
Source: Legal Medicine - July 15, 2017 Category: Forensic Medicine Authors: Frank Oliver Henes, Marc Regier, Peter Bannas, Marlen Henker, Axel Heinemann, Jan Sperhake, Philipp G.C. Begemann, Gerhard Adam, Michael Groth Source Type: research
Postmortem diagnosis of sepsis: A preliminary immunohistochemical study with an anti-procalcitonin antibody
Post mortem diagnosis of sepsis, especially in the forensic field, is a problem that presents several difficulties. Those difficulties are often linked to the lack of complete and adequate health records that could suggest or demonstrate the falling of the patient into a septic state. Moreover, in sepsis, pathological findings in sepsis are often nonspecific, and they are often compatible with other different clinical pictures [1]. (Source: Legal Medicine)
Source: Legal Medicine - July 12, 2017 Category: Forensic Medicine Authors: Aniello Maiese, Franca Del Nonno, Marco Dell'Aquila, Mario Moauro, Andrea Baiocchini, Antonio Mastracchio, Giorgio Bolino Source Type: research
Sudden perinatal death due to rupture of congenital cardiac diverticulum. pathological findings and medico-legal investigations in malpractice charge
Congenital diverticoli of the left ventricle, defined as protrusions of the free wall [1], are cardiac abnormalities with a fibrous or muscular [2] structure, very rare [3 –9], often undetected during instrumental investigations and therefore lately identified [3]. Their sudden rupture is associated to high rates of morbidity and mortality [10], leading affected patients to unexpected death [5,10]. Most of the times these malformations are located to the left ventri cle [11], even though they can be found in every cardiac district (diverticulosis) [12]. (Source: Legal Medicine)
Source: Legal Medicine - July 11, 2017 Category: Forensic Medicine Authors: Matteo Marchesi, Michele Boracchi, Guendalina Gentile, Francesca Maghin, Riccardo Zoja Tags: Case Report Source Type: research
Corrigendum to “Age estimation by an analysis of spheno-occipital synchondrosis using cone-beam computed tomography” [Legal Med. (Tokyo) 18 (2016) 13–19]
The correct representations of the authors ’ forenames and surnames is mentioned above. (Source: Legal Medicine)
Source: Legal Medicine - July 7, 2017 Category: Forensic Medicine Authors: A. Sinanoglu, H. Demirturk Kocasarac, M. Noujeim Source Type: research
Changes in illicit, licit and stimulant designer drug use patterns in South-East Hungary between 2008 and 2015
The appearance of designer drugs on the European illicit market started with fentanyl analogues [1 –3] or pyrovalerone-like synthetic cathinones [4], but mass spreading of stimulant designer drugs (SDDs) began with mephedrone in 2009 [4–7]. As soon as mephedrone was classified as an illicit drug in 2010-11, increasing number of new stimulant substances (methylone, methylendioxy-pirovalerone ( MDPV), 4-methylcathinone (4-MEC), 4-fluoro-methcathinone (4-FMC), etc.) appeared [8] as its still legal alternatives. (Source: Legal Medicine)
Source: Legal Medicine - July 6, 2017 Category: Forensic Medicine Authors: Zs ófia Árok, Tamás Csesztregi, Éva Sija, Tibor Varga, Éva M. Kereszty, Réka Anita Tóth, László Institóris Source Type: research
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(Source: Legal Medicine)
Source: Legal Medicine - July 1, 2017 Category: Forensic Medicine Source Type: research
A finding in genetic polymorphism analysis study: A case of non-mosaic 47, xxx without manifestations
A large number of short tandem repeat (STR) markers spanning the entire human X chromosome have been described and established for use in forensic genetic testing, kinship analyses and identification of complicated relationships [1,2]. The X-STRs are used as markers in identification of the genetic information of populations [3-6].The use of autosomal markers is a typical strategy to disclose population patterns, as these markers account for both paternal and maternal inheritance. Nevertheless, X-Chromosome is gaining significant importance in population and forensic genetic studies due to the special transmission property...
Source: Legal Medicine - June 30, 2017 Category: Forensic Medicine Authors: Xingyi Yang, Zilan Ye, Xiaofang Zhang, Huijun Wang, Chao Liu Source Type: research
A new challenge in forensic toxicology exemplified by a case of murder under the influence of a synthetic cannabinoid - AM-2201
Synthetic cannabinoids, commonly known as smokable herbal “spice” and “K2”, are the most popular designer drugs [1–3]. Although their labels formally read “not for human consumption”, in practice such substances are used in order to achieve a psychological effect that imitates that of Δ9-THC [4]. There are no structural similarities in the s ynthetic cannabinoids with Δ9-THC; however, they are strong agonists of the cannabinoid receptors CB1 and CB2, as well as the N-methyl-D-aspartate receptor [5]. (Source: Legal Medicine)
Source: Legal Medicine - June 26, 2017 Category: Forensic Medicine Authors: Sebastian Rojek, Ma łgorzata Kłys, Martyna Maciów-Głąb, Karol Kula Source Type: research
Influence of hypo- and hyperthermia on death time estimation – a simulation study
Death time estimation is one of the forensic key competencies in homicide investigations. Different methods can be applied ([1 –3]), but due to the homoeothermality of humans temperature based methods should provide the most reliable death time estimates for short post-mortem intervals. (Source: Legal Medicine)
Source: Legal Medicine - June 26, 2017 Category: Forensic Medicine Authors: H. Muggenthaler, M. MHubig, S. Schenkl, G. Mall Source Type: research
Sex determination based on a thoracic vertebra and ribs evaluation using clinical chest radiography
Shape and size of the skull, pelvis, and humerus have often been used for sex determination in forensic medicine [1 –8]. However, skeletal bones are not always complete in forensic cases due to conditions within the burial environment, and only parts of bones are found occasionally [9]. In such cases, it is desirable to discriminate personal information, such as age, height, and sex, from the bones available. S ome reports have shown that features of vertebrae and ribs, including the 1st and 2nd cervical vertebrae, 12th thoracic vertebra, all lumbar vertebrae, and the 1st and 4th ribs, could be useful for sex determinati...
Source: Legal Medicine - June 22, 2017 Category: Forensic Medicine Authors: Shun Tsubaki, Junji Morishita, Yosuke Usumoto, Kyoko Sakaguchi, Yusuke Matsunobu, Yusuke Kawazoe, Miki Okumura, Noriaki Ikeda Source Type: research
Comparison of three-dimensional facial morphology between upright and supine positions employing three-dimensional scanner from live subjects
Forensic facial reconstructions such as the anthropometric (American) method [1], the combined (Manchester) method [2] and the automated methods [3] all require the use of average tissue thickness data taken from a related population. Studies have collected tissue thickness data from Magnetic Resonance Imaging (MRI) [4 –6], Computed Tomography (CT) [7–11], Cone-Beam Computed Tomography (CBCT) [12,13], ultrasound [14–17], lateral radiographs [18–21] or from cadavers [22–24]. (Source: Legal Medicine)
Source: Legal Medicine - June 22, 2017 Category: Forensic Medicine Authors: Ozgur Bulut, Ching-Yiu Jessica Liu, Fatih Koca, Caroline Wilkinson Source Type: research
Four intracranial injury cases with peripapillary scleral hemorrhage —Reconsidering the mechanism of hemorrhage
Ocular findings are present in approximately 70% of deaths due to child abuse [1]. Peripapillary scleral hemorrhage was first mentioned in 1990 as a scleral hemorrhage surrounding the optic nerves in abusive head trauma cases [1]. Peripapillary scleral hemorrhage is believed to be an important finding suggesting shaken baby syndrome [2 –4]. However, it was recently reported that peripapillary scleral hemorrhage was found in accidental head trauma cases [5,6]. Herein, we report four intracranial injury cases in which peripapillary scleral hemorrhage was found, and discuss the potential mechanisms involved. (Source: Legal Medicine)
Source: Legal Medicine - June 6, 2017 Category: Forensic Medicine Authors: Toru Oshima, Hiroshi Yoshikawa, Yoshiro Koda, Maki Ohtani, Shoko Tsukamoto, Sohtaro Mimasaka Tags: Case Report Source Type: research
Four intracranial injury cases with peripapillary scleral hemorrhage — reconsidering the mechanism of hemorrhage
Ocular findings are present in approximately 70% of deaths due to child abuse [1]. Peripapillary scleral hemorrhage was first mentioned in 1990 as a scleral hemorrhage surrounding the optic nerves in abusive head trauma cases [1]. Peripapillary scleral hemorrhage is believed to be an important finding suggesting shaken baby syndrome [2 –4]. However, it was recently reported that peripapillary scleral hemorrhage was found in accidental head trauma cases [5,6]. Herein, we report four intracranial injury cases in which peripapillary scleral hemorrhage was found, and discuss the potential mechanisms involved. (Source: Legal Medicine)
Source: Legal Medicine - June 6, 2017 Category: Forensic Medicine Authors: Toru Oshima, Hiroshi Yoshikawa, Yoshiro Koda, Maki Ohtani, Shoko Tsukamoto, Sohtaro Mimasaka Tags: Case Report Source Type: research
