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A case of Ramsay Hunt syndrome diagnosed after kidney transplantation
We report the first case of Ramsay Hunt syndrome (RHS) diagnosed after kidney transplantation in Korea. RHS is a disease caused by latent varicella zoster characterized to involve geniculate ganglion of the seventh cranial nerve. Patients who have undergone kidney transplantation can be easily affected by viral infections because of their immune-compromised status. A 35-year-old man with hypertensive end-stage renal disease underwent kidney transplantation. Two months after surgery, the recipient was diagnosed with RHS and treated with antivirals and steroids. However, after using the antiviral agents for the recommended d...
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

The gut–kidney connection in advanced chronic kidney disease
Publication date: Available online 2 October 2015 Source:Kidney Research and Clinical Practice Author(s): Reiko Inagi (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

Overhydration measured by bioimpedance analysis and the survival of patients on maintenance hemodialysis: a single-center study
Conclusion The ratio of OH/ECW volume measured with body composition monitor is related to the overall survival of end-stage renal disorder patients who started maintenance hemodialysis. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

Endovascular interventions for central vein stenosis
Publication date: Available online 12 November 2015 Source:Kidney Research and Clinical Practice Author(s): Anil K. Agarwal Central vein stenosis is common because of the placement of venous access and cardiac intravascular devices and compromises vascular access for dialysis. Endovascular intervention with angioplasty and/or stent placement is the preferred approach, but the results are suboptimal and limited. Primary patency after angioplasty alone is poor, but secondary patency can be maintained with repeated angioplasty. Stent placement is recommended for quick recurrence or elastic recoil of stenosis. Primary p...
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

Effect of blood pressure and glycemic control on the plasma cell-free DNA in hemodialysis patients
Conclusions In patients with HD, cfDNA is elevated in diabetic patients and patients with cardiovascular diseases. Uncontrolled hypertension and poor glycemic control are independent determinants for the elevated cfDNA. Our data suggest that cfDNA might be a marker of vascular injury rather than proinflammatory condition in HD patients. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

Comparison of estimated glomerular filtration rate equations at the time of hemodialysis initiation
Conclusions The eGFR at HD initiation are significantly different according to the used eGFR equations, and the corrected Cockcroft–Gault equation may be the best in defining the eGFR at HD initiation. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

Posterior nutcracker phenomenon with Down syndrome
Publication date: Available online 12 November 2015 Source:Kidney Research and Clinical Practice Author(s): Eun Sil Koh, Min Young Kim, Yoon Sik Chang, Sungjin Chung (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

Physiology and pathophysiology of cyclooxygenase-2 and prostaglandin E2 in the kidney
Publication date: Available online 12 November 2015 Source:Kidney Research and Clinical Practice Author(s): Rikke Nørregaard, Tae-Hwan Kwon, Jørgen Frøkiær The cyclooxygenase (COX) enzyme system is the major pathway catalyzing the conversion of arachidonic acid into prostaglandins. Prostaglandins are lipid mediators implicated in a variety of physiological and pathophysiological processes in the kidney, including renal hemodynamics, body water and sodium balance, and the inflammatory injury characteristic in multiple renal diseases. Since the beginning of 1990s, it has been confirmed that COX exists in 2 isof...
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

Cardiac Arrest Caused by Nafamostat Mesilate
Publication date: Available online 12 November 2015 Source:Kidney Research and Clinical Practice Author(s): Hyo Shik Kim, Kyung Eun Lee, Ji Hyun Oh, Chan Sung Jung, Dughyun Choi, Yunsuek Kim, Jin Seok Jeon, Dong Cheol Han, Hyunjin Noh A 65-year-old man was transferred from the Department of Vascular Surgery to Nephrology because of cardiac arrest during hemodialysis. He underwent incision and drainage for treatment of a buttock abscess. Nafamostat mesilate was used as an anticoagulant for hemodialysis to address bleeding from the incision and drainage site. Sudden cardiac arrest occurred after 15 minu...
Source: Kidney Research and Clinical Practice - December 1, 2015 Category: Urology & Nephrology Source Type: research

RNA sequencing of the nephron transcriptome: A technical note
Publication date: Available online 8 October 2015 Source:Kidney Research and Clinical Practice Author(s): Jae Wook Lee To understand the functions of the kidney, the transcriptome of each part of the nephron needs to be profiled using a highly sensitive and unbiased tool. RNA sequencing (RNA-seq) has revolutionized transcriptomic research, enabling researchers to define transcription activity and functions of genomic elements with unprecedented sensitivity and precision. Recently, RNA-seq for polyadenylated mRNAs (poly(A)’-mRNAs) and classical microdissection were successfully combined to investigate the transcript...
Source: Kidney Research and Clinical Practice - October 9, 2015 Category: Urology & Nephrology Source Type: research

Successfully treated isolated renal artery pseudoaneurysm in a patient with Behçet disease
We report a case of renal artery pseudoaneurysm induced by Behçet disease and treated successfully with coil embolization. A 56-year-old woman with Behçet disease presented with an incidental left renal artery pseudoaneurysm measuring 18mm. We successfully performed endovascular treatment with coil embolization instead of surgical treatment. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - October 3, 2015 Category: Urology & Nephrology Source Type: research

The gut-kidney connection in advanced CKD
Publication date: Available online 2 October 2015 Source:Kidney Research and Clinical Practice Author(s): Reiko Inagi (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - October 3, 2015 Category: Urology & Nephrology Source Type: research

Antineutrophil cytoplasmic antibody–negative pauci-immune glomerulonephritis with massive intestinal bleeding
We report a case of antineutrophil cytoplasmic antibody–negative pauci-immune glomerulonephritis with massive intestinal bleeding and cerebral hemorrhage. (Source: Kidney Research and Clinical Practice)
Source: Kidney Research and Clinical Practice - September 11, 2015 Category: Urology & Nephrology Source Type: research

A case of peritoneal dialysis-associated peritonitis by Rothia mucilaginosa
Publication date: Available online 29 July 2015 Source:Kidney Research and Clinical Practice Author(s): Byeong Gwan Kim, A Young Cho, Sang Sun Kim, Seong Hee Lee, Hong Shik Shin, Hyun Ju Yoon, Jeong Gwan Kim, In O Sun, Kwang Young Lee Rothia muciliaginosa (R. mucilaginosa) is a facultative, Gram-positive coccus that is considered to be part of the normal flora of the mouth and respiratory tract. There are sporadic reports of the organism causing endocarditis in patients with heart valve abnormalities, as well as meningitis, septicemia, and pneumonia associated with intravenous drug abuse. However, it...
Source: Kidney Research and Clinical Practice - September 11, 2015 Category: Urology & Nephrology Source Type: research

Current progress in ABO-incompatible kidney transplantation
Publication date: Available online 20 August 2015 Source:Kidney Research and Clinical Practice Author(s): Tai Yeon Koo, Jaeseok Yang ABO-incompatible kidney transplantation (ABOi KT) was introduced to expand the donor pool and minimize shortage of kidneys for transplantation. Because improved outcomes of ABOi KT were reported in Japan in the early 2000s, the number of ABOi KTs has been increasing worldwide. In addition, a better understanding of immune pathogenesis and subsequent aggressive immunosuppression has helped to make effective desensitization protocols. Current strategies of ABOi KT consist of pretranspla...
Source: Kidney Research and Clinical Practice - September 11, 2015 Category: Urology & Nephrology Source Type: research