Preferential Cyclooxygenase 2 Inhibitors as a Nonhormonal Method of Emergency Contraception: A Look at the Evidence
Conclusions:
Insufficient evidence exists to fully support the use of preferential COX-2 inhibitors as a form of emergency contraception. Although all trials resulted in a decrease in ovulatory cycles, outcomes varied between dosing strategies and agents used. A lack of homogeneity in these studies makes comparisons difficult. However, success of meloxicam in multiple trials warrants further study. Larger human trials are necessary before the clinical utility of this method of emergency contraception can be fully appreciated. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Weiss, E. A., Gandhi, M. Tags: Review Articles Source Type: research
Alternative Agents in Type 1 Diabetes in Addition to Insulin Therapy: Metformin, Alpha-Glucosidase Inhibitors, Pioglitazone, GLP-1 Agonists, DPP-IV Inhibitors, and SGLT-2 Inhibitors
Insulin is the mainstay of current treatment for patients with type 1 diabetes mellitus (T1DM). Due to increasing insulin resistance, insulin doses are often continually increased, which may result in weight gain for patients. Medications currently approved for the treatment of type 2 diabetes offer varying mechanisms of action that can help to reduce insulin resistance and prevent or deter weight gain. A MEDLINE search was conducted to review literature evaluating the use of metformin, alpha-glucosidase inhibitors, pioglitazone, glucagon-like peptide 1 agonists, dipeptidyl peptidase, and sodium-dependent glucose transport...
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: DeGeeter, M., Williamson, B. Tags: Research Articles Source Type: research
Adherence With Therapeutic Regimens: Behavioral and Pharmacoeconomic Perspectives
This article will discuss the development of a brief model for patient counseling with specific techniques illustrated for pharmacists based on empirical findings that have demonstrated effectiveness in the adherence research literature. In addition, the article will address the measurement of the economic impact of medication nonadherence and propose a framework for assessing the cost-effectiveness of pharmacist counseling to increase adherence. The problem of nonadherence has significant effects upon health care expenditures through increase in physician’s visits, emergency department incidents, rehospitalizations,...
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Giannetti, V. J., Kamal, K. M. Tags: Research Articles Source Type: research
Evaluation of Adverse Drug Events and Medication Discrepancies in Transitions of Care Between Hospital Discharge and Primary Care Follow-Up
Approximately two-thirds of adverse events posthospital discharge are due to medication-related problems. Medication reconciliation is a strategy to reduce medication errors and improve patient safety. Objective: To evaluate adverse drug events (ADEs), potential ADEs (pADEs), and medication discrepancies occurring between hospital discharge and primary care follow-up in an academic family medicine clinic. Adult patients recently discharged from the hospital were seen by a pharmacist for medication reconciliation between September 1, 2011, and November 30, 2012. The pharmacist identified medication discrepancies and pADEs o...
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Armor, B. L., Wight, A. J., Carter, S. M. Tags: Research Articles Source Type: research
Overestimation of Glomerular Filtration Rate Among Critically Ill Adults With Hospital-Acquired Oligoanuric Acute Kidney Injury
Conclusion:
Creatinine-based equations overestimated GFR in ICU patients with hAKI. This study highlights a population at risk of medication misadventures in whom systems optimization should be considered. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Frazee, E. N., Personett, H. A., Wood-Wentz, C. M., Herasevich, V., Lieske, J. C., Kashani, K. B. Tags: Research Articles Source Type: research
Ceftriaxone Potentiates Warfarin Activity Greater Than Other Antibiotics in the Treatment of Urinary Tract Infections
Conclusion:
Ceftriaxone interacts with warfarin to increase a patient’s INR value more than other commonly administered antibiotics for UTI treatment. Other antibiotics should be preferred for UTI treatment in patients on warfarin. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Saum, L. M., Balmat, R. P. Tags: Research Articles Source Type: research
Pharmacists as Members of the Rapid Response Team
Conclusion:
With a minimal time commitment, pharmacists can be valuable members of the RRT. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Groth, C. M., Acquisto, N. M. Tags: Research Articles Source Type: research
Identifying and Communicating Clinically Meaningful Drug-Drug Interactions
Conclusions:
Clinically meaningful DDIs are common in patients with complex medication regimens. A systematic approach for identifying DDIs, determining clinical significance, formulating patient-specific recommendations, and communicating recommendations is important in pharmacy practice. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Nelson, S. D., LaFleur, J., Hunter, E., Archer, M., Steinvoort, C., Maden, C., Oderda, G. M. Tags: Research Articles Source Type: research
Factors Influencing Enrollment in the Medication Therapy Management Clinic at an Academic Ambulatory Care Clinic
Conclusion:
This study demonstrated that distance from MTMC is the most common barrier in patient enrollment; therefore, strategies to improve patient access are necessary. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Shah, M., Tilton, J., Kim, S. Tags: Research Articles Source Type: research
Language Concordance as a Determinant of Patient Outcomes in a Pharmacist-Managed Cardiovascular Risk Reduction Clinic
Conclusions:
These results suggest that similar clinical outcomes between ES and SS patients may be achieved with the ability of pharmacists to speak the same language as their patients. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Gonzalvo, J. D., Sharaya, N. H. Tags: Research Articles Source Type: research
Impact of Pharmacist Involvement in Early Identification and Enrollment in Patient Assistance Programs on CMV Outcomes in Transplantation
Conclusion:
Early identification and enrollment of patients in PAPs reduces the incidence of CMV viremia. Pharmacists play a crucial role in this process. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Byrns, J. S., Pilch, N. W., Taber, D. J. Tags: Research Articles Source Type: research
Comments on: An Update on the Management of Pulmonary Arterial Hypertension and the Pharmacists Role
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 17, 2016 Category: Drugs & Pharmacology Authors: Gibbard, R. S. Tags: Letter to the Editor Source Type: research
Presidential Address: Do the Right Thing... Support Expansion of the Role of Pharmacy Technicians
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - January 11, 2016 Category: Drugs & Pharmacology Authors: Seyse, S. Tags: New York State Council of Health-system Pharmacists Section Source Type: research
Clinical Pearls in Using Antiarrhythmic Drugs in the Outpatient Setting
A role for oral antiarrhythmic drugs (AADs) remains in clinical practice for patients with atrial and ventricular arrhythmias in spite of advances in nonpharmacologic therapy. Pharmacists play a vital role in the appropriate use of AAD dosing, administration, adverse effects, interactions, and monitoring. Pharmacists who are involved in providing care to patients with cardiac arrhythmias must remain updated regarding the efficacy and safety of the most commonly used AADs. This review will address key issues for appropriate initiation and maintenance of commonly selected Vaughan-Williams Class Ic and III agents in the outpa...
Source: Journal of Pharmacy Practice - January 11, 2016 Category: Drugs & Pharmacology Authors: Parker, M. H., Sanoski, C. A. Tags: Cardiology Pharmacotherapy Source Type: research
An Update on the Management of Pulmonary Arterial Hypertension and the Pharmacists Role
Pulmonary arterial hypertension (PAH) is a rare medical condition that significantly shortens life expectancy. The lack of understanding and complexity of treatments frequently lead to delays in diagnosis and treatment of patients. This is worsened by the gap in medical education related to the rarity of disease and the subspecialty nature of management. Advancements in diagnostics and treatment in recent years makes a review of this nature important and timely. Understanding the specialty nature of drug therapy, the complexities of managing prostacyclin analogs, and treatment algorithms are essential for pharmacists carin...
Source: Journal of Pharmacy Practice - January 11, 2016 Category: Drugs & Pharmacology Authors: Macaulay, T. E., Covell, M. B., Pogue, K. T. Tags: Cardiology Pharmacotherapy Source Type: research
