College of Psychiatric and Neurologic Pharmacists 2014 Poster Abstracts
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Tags: CPNP 2014 Poster Abstracts Source Type: research
Introduction to the CPNP 2014 Poster Abstracts
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Authors: Chavez, B. Tags: CPNP 2014 Poster Abstracts Source Type: research
NYSCHP Annual Assembly 2014 Poster Abstracts
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Tags: New York State Council of Health-system Pharmacists Section Source Type: research
Presidential Address: We Can Move Mountains, One Step at a Time
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Authors: Shlom, E. A. Tags: New York State Council of Health-system Pharmacists Section Source Type: research
Thrombophilia Screening
Although controversial, screening for thrombophilia has become common. Testing for antiphospholipid antibodies is indicated in order to guide treatment decisions if there is clinical suspicion for antiphospholipid syndrome. The utility of identifying other thrombophilias in symptomatic venous thromboembolism (VTE) is questionable, as the risk of recurrence does not appear to be increased by an appreciable degree with the most common disorders (heterozygosity for factor V Leiden or prothrombin mutation). Although recurrence appears to be increased in those with homozygous or multiple abnormalities and potentially deficienci...
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Authors: Hornsby, L. B., Armstrong, E. M., Bellone, J. M., Treadway, S., Phillippe, H. M. Tags: Thrombophilia Source Type: research
Pregnancy-Related Venous Thromboembolism
Pregnancy is associated with an increased risk of venous thromboembolism (VTE), with a reported incidence ranging from 0.49 to 2 events per 1000 deliveries. Risk factors include advanced maternal age, obesity, smoking, and cesarian section. Women with a history of previous VTE are at a 4-fold higher risk of recurrent thromboembolic events during subsequent pregnancies. Additionally, the presence of concomitant thrombophilia, particularly factor V Leiden (homozygosity), prothrombin gene mutation (homozygosity), or antiphospholipid syndrome (APS), increases the risk of pregnancy-related VTE. Low-molecular-weight heparin (LMW...
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Authors: Armstrong, E. M., Bellone, J. M., Hornsby, L. B., Treadway, S., Phillippe, H. M. Tags: Thrombophilia Source Type: research
Acquired Thrombophilia
Acquired thrombophilia is associated with an increased risk of venous thromboembolism (VTE). Antiphospholipid syndrome (APS) is the most prevalent acquired thrombophilia and is associated with both venous and arterial thromboses. Human immunodeficiency virus (HIV) is another form of acquired thrombophilia. Risk factors associated with VTE in this population include those related to the disease itself, host factors, and the pharmacotherapy for HIV. A significant proportion of VTE events occur in patients with malignancies. There is an increase in mortality associated with patients having cancer who experience VTE when compa...
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Authors: Armstrong, E. M., Bellone, J. M., Hornsby, L. B., Treadway, S., Phillippe, H. M. Tags: Thrombophilia Source Type: research
Inherited Thrombophilia
Thrombophilia alters normal hemostasis, shifting the balance in favor of thrombus formation. Inherited conditions include factor V Leiden (FVL), prothrombin G20210A mutation, deficiencies in natural anticoagulants (antithrombin [AT], protein C, and protein S), hyperhomocysteinemia, and elevations in clotting factors (factors VIII and XI). Although FVL and prothrombin mutation are common disorders, deficiencies in the natural anticoagulants are rare. The risk of initial thrombosis conferred by inherited thrombophilia varies with the highest risk in those homozygous for either FVL or prothrombin mutation, or with AT deficien...
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Authors: Phillippe, H. M., Hornsby, L. B., Treadway, S., Armstrong, E. M., Bellone, J. M. Tags: Thrombophilia Source Type: research
Thrombophilia Issue
(Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - May 22, 2014 Category: Drugs & Pharmacology Authors: Mahan, C. E., Hornsby, L. B., Burnett, A., Marcy, T. R., Conway, S. E. Tags: Thrombophilia Source Type: research
Drug Interaction Between Phenytoin and Valproic Acid in a Child With Refractory Epilepsy: A Case Report
Discussion:
Despite the appropriate phenytoin concentration in the capsules, the patient presented with phenytoin toxicity. This toxicity likely resulted from the drug interaction between phenytoin and valproic acid that leads to phenytoin displacement from plasmatic proteins and inhibits phenytoin metabolism, thereby increasing the concentration of free drug in the serum. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 19, 2014 Category: Drugs & Pharmacology Authors: Carvalho, I. V., Carnevale, R. C., Visacri, M. B., Mazzola, P. G., de Fatima Lopes Ambrosio, R., Reis, M. C. d., de Queiroz, R. A., Moriel, P. Tags: Adverse Drug Events Source Type: research
Adverse Drug Events in Critically Ill Patients With Cancer: Incidence, Characteristics, and Outcomes
Conclusion:
Critically ill patients with cancer are at high risk of developing ADEs. Strategies that reduce the incidence and severity of ADEs are essential to improve the outcomes of this patient population. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 19, 2014 Category: Drugs & Pharmacology Authors: Nazer, L. H., Hawari, F., Al-Najjar, T. Tags: Adverse Drug Events Source Type: research
Intensive Care Unit Delirium: A Review of the Literature
Conclusion:
Clinicians should become familiar with tools to identify delirium in order to initiate treatment and remove mitigating factors early in hospitalization to prevent delirium. Pharmacists are in a unique position to reduce delirium through minimization of medication-related risk factors and development of protocols. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 19, 2014 Category: Drugs & Pharmacology Authors: Kalabalik, J., Brunetti, L., El-Srougy, R. Tags: Reviews Source Type: research
Improving Medication Adherence Among Patients With Type 2 Diabetes
This article will examine the causes of nonadherence in T2DM and the integral role that pharmacists can play in improving medication adherence and persistence. Strategies for improving adherence, such as patient education, motivational interviewing, medication therapy management programs, and collaborative management, will also be considered. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 19, 2014 Category: Drugs & Pharmacology Authors: Meece, J. Tags: Reviews Source Type: research
Economic Implications of Inadequate Treatment of Venous Thromboembolism and Potential Solutions
Venous thromboembolism (VTE) is a common and serious medical complication among medical and surgical patients, both in the hospital and postdischarge. Patients with venous stasis or vascular damage or those with underlying hypercoagulable disorders, including cancer, are at risk of developing VTE. The clinical consequences of inadequate treatment of VTE can result in significant patient morbidity and mortality. The direct health care costs and indirect societal costs related to VTE and its complications are high. Traditional anticoagulants can reduce recurrent VTE but they present costly management challenges. Oral anticoa...
Source: Journal of Pharmacy Practice - March 19, 2014 Category: Drugs & Pharmacology Authors: Dobesh, P. P. Tags: Reviews Source Type: research
Emergency Contraception, Institutional Conscience, and Pharmacy Practice
"Emergency contraception" case law from the state of Washington is reviewed and analyzed. Important legal, social policy, and professional ethical questions are considered with focus on professional and institutional conscientious objection to participating in this therapy. (Source: Journal of Pharmacy Practice)
Source: Journal of Pharmacy Practice - March 19, 2014 Category: Drugs & Pharmacology Authors: Card, R. F., Williams, K. G. Tags: Pharmacy Law Source Type: research
