The NMatrix, a new method of presenting statistics, displays the characteristics of medicines with similar effects used in the treatment of lumbar spinal stenosis concisely and clearly, facilitating the selection of appropriate medications
Conclusions The NMatrix concisely and clearly displays the characteristics of “medicines with similar effects” for the treatment of lumbar spinal stenosis, and can help physicians to choose the optimal medicine based on rational criteria for individual patients, according to their symptoms and progress. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - April 10, 2015 Category: Orthopaedics Source Type: research

Periprosthetic BMD after cemented and uncemented total hip arthroplasty: a 10-year follow-up study
Abstract Background and purposes Insertion of a metallic implant into the femur changes bone loading conditions and results in remodeling of femoral bone. To quantify these changes in bone mineral density (BMD) after total hip arthroplasty, we monitored femoral bone with dual X-ray absorptiometry (DXA). Materials and methods The periprosthetic bone mineral density was measured in seven Gruen zones at scheduled time intervals during a 10-year follow-up. A total of 38 patients went through ...
Source: Journal of Orthopaedic Science - April 9, 2015 Category: Orthopaedics Source Type: research

Modified Mostardi approach with ultra-high-molecular-weight polyethylene tape for total hip arthroplasty provides a good rate of union of osteotomized fragments
Conclusions The modified Mostardi approach using ultra-high molecular weight polyethylene tape can promote successful union of the osteotomized fragment. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - April 3, 2015 Category: Orthopaedics Source Type: research

Gallic acid can play a chondroprotective role against AGE-induced osteoarthritis progression
Conclusion The results of this study confirmed the chondroprotective role of GA and provide a potential drug for the relief of OA. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 31, 2015 Category: Orthopaedics Source Type: research

Application of the polystyrene model made by 3-D printing rapid prototyping technology for operation planning in revision lumbar discectomy
Conclusion Using the 3-D printing technology before revision lumbar discectomy may reduce the operation time and the perioperative blood loss. There does not appear to be a benefit to using the technology with respect to clinical outcomes. Future prospective studies are needed to further elucidate the efficacy of this emerging technology. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 31, 2015 Category: Orthopaedics Source Type: research

hBMP-2 and hTGF-β1 expressed in implanted BMSCs synergistically promote the repairing of segmental bone defects
Conclusion hBMP-2 and hTGF-β1 can synergistically improve the bone repair process. Our results suggest a potential clinical value of combining hBMP-2 and hTGF-β1 in repairing bone defects. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 27, 2015 Category: Orthopaedics Source Type: research

Perioperative alendronate, risedronate, calcitonin and indomethacin treatment alters femoral stem fixation and periprosthetic bone mineral density in ovariectomized rats
Conclusions This study showed that perioperative treatment with bisphosphonates and calcitonin improved the BMD around the stems and implant stability. Although bisphosphonates increased the BMD more than calcitonin, there was no difference in implant stability. Indomethacin markedly decreased the periprosthetic BMD and implant stability. The main clinical significance of our study was the finding about the need to strictly avoid long-term use of high-dose nonsteroidal antiinflammatory drugs for patients who have major joint arthritis and a previous history of arthroplasty. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 25, 2015 Category: Orthopaedics Source Type: research

Simultaneous ankle arthroscopy and hindfoot endoscopy for combined anterior and posterior ankle impingement syndrome in professional athletes
Conclusion Simultaneous ankle arthroscopy and hindfoot endoscopy for combined AAIS and PAIS enables professional athletes to return to athletic activity. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 23, 2015 Category: Orthopaedics Source Type: research

Falls in patients after total hip arthroplasty in Japan
Conclusions Thus, patients have an increased risk for falls and fall-induced injuries after THA. Falls in post-THA patients are associated with medication and shorter postoperative duration. Therefore, it is essential to prevent falls in patients who have undergone THA, particularly during the early postoperative period and among patients administered medications. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 23, 2015 Category: Orthopaedics Source Type: research

D-dimer levels to screen for venous thromboembolism in patients with fractures caused by high-energy injuries
Conclusions D-dimer can be used as a VTE screening tool in patients with fractures caused by high-energy injuries. Our results suggested that D-dimer analysis to predict VTE was useful in patients with a pelvic fracture or multiple fractures. Our results also suggested that it was less useful for predicting VTE in patients with an isolated lower extremity fracture. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 23, 2015 Category: Orthopaedics Source Type: research

Intramedullary nailing versus minimally invasive plate osteosynthesis for distal extra-articular tibial fractures: a prospective randomized clinical trial
Conclusions Results of our study showed that both treatment methods have similar therapeutic efficacy regarding functional outcomes and can be used safely for extra-articular distal tibial shaft fractures, and none of the techniques had a major advantage over the other. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 21, 2015 Category: Orthopaedics Source Type: research

Weight bearing the same day versus non-weight bearing for 4 weeks in Achilles tendon rupture
Conclusion This study showed that a well-conducted early-weight-bearing treatment has good clinical outcomes, with a complication rate no higher than non-weight-bearing treatment. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 14, 2015 Category: Orthopaedics Source Type: research

Anatomic ACL reconstruction: rectangular tunnel/bone–patellar tendon–bone or triple-bundle/semitendinosus tendon grafting
Abstract Anatomic ACL reconstruction is the reasonable approach to restore stability without loss of motion after ACL tear. To mimic the normal ACL like a ribbon, our preferred procedures is the anatomic rectangular tunnel (ART) technique with a bone-patellar tendon-bone (BTB) graft or the anatomic triple bundle (ATB) procedure with a hamstring (HS) tendon graft. It is important to create tunnel apertures inside the attachment areas to lessen the tunnel widening. To identify the crescent-shaped ACL femoral attachment area, the upper cartilage margin, the posterior cartilage margin and the resident’s rid...
Source: Journal of Orthopaedic Science - March 11, 2015 Category: Orthopaedics Source Type: research

The effect of administration of double stranded MicroRNA-210 on acceleration of Achilles tendon healing in a rat model
Conclusion The current study showed that single local injection of synthetic miR-210 promotes Achilles tendon healing in the early phase. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 11, 2015 Category: Orthopaedics Source Type: research

Postoperative evaluation of drill holes for arthroscopic Bankart repair with suture anchors by the use of computed tomography
Conclusions Before inserting an implant in the anterior–inferior area, the angle between the drill guide and the glenoid surface in the oblique coronal plane view should be carefully checked to ensure that the length of the hole inside the glenoid bone is adequate. (Source: Journal of Orthopaedic Science)
Source: Journal of Orthopaedic Science - March 6, 2015 Category: Orthopaedics Source Type: research