Journal of Geriatric Psychiatry and Neurology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Dependence Scale for Alzheimer's Disease: Relationship With Other Clinical Indicators and Psychometric Properties
The objective of this cross-sectional and multicenter study was to evaluate the psychometric properties of the Spanish version of the Dependence Scale (DS) and to assess the relationship between dependence and clinical measures according to disease severity. Medical comorbidities, cognitive status and functional status, behavior, dependence, caregiver burden, and medical and social resources were assessed using standardized instruments. The sample consisted of 343 patients (32.1% mild, 36.7% moderate, and 31.2% severe), the mean age was 78.9 years (standard deviation = 7.4), and 67.0% were women. Criterion and construct va...
Source: Journal of Geriatric Psychiatry and Neurology - April 28, 2015 Category: Genetics & Stem Cells Authors: Garre-Olmo, J., Vilalta-Franch, J., Calvo-Perxas, L., Monserrat-Vila, S., Lopez-Pousa, S., the CoDep-AD Study Group Tags: Articles Source Type: research

Semantic Memory Impairment for Biological and Man-Made Objects in Individuals With Amnestic Mild Cognitive Impairment or Late-Life Depression
Conclusion: This study is the first to show that aMCI/D+ is associated with object-based semantic memory impairment. These results support the view that semantic deficits in aMCI are associated with concomitant depressive symptoms. However, depressive symptoms alone do not account exclusively for semantic impairment, since patients with LLD showed no semantic memory deficit. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - April 28, 2015 Category: Genetics & Stem Cells Authors: Callahan, B. L., Joubert, S., Tremblay, M.-P., Macoir, J., Belleville, S., Rousseau, F., Bouchard, R. W., Verret, L., Hudon, C. Tags: Articles Source Type: research

Clinicopathological Study of Patients With C9ORF72-Associated Frontotemporal Dementia Presenting With Delusions
Conclusion: C9ORF72 carriers with well-defined delusions likely associated with additional pathologies and parietal atrophy in neuroimaging. Patients presenting with middle-aged onset of delusions should be screened for C9ORF72 mutations, especially if family history and parkinsonism are present. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - April 28, 2015 Category: Genetics & Stem Cells Authors: Shinagawa, S., Naasan, G., Karydas, A. M., Coppola, G., Pribadi, M., Seeley, W. W., Trojanowski, J. Q., Miller, B. L., Grinberg, L. T. Tags: Articles Source Type: research

Association Between Polymorphisms of the Insulin-Degrading Enzyme Gene and Late-Onset Alzheimer Disease
The insulin-degrading enzyme (IDE) gene is a strong positional and biological candidate for late-onset Alzheimer disease (LOAD) susceptibility, with recent studies independently demonstrating an association between IDE gene variants and LOAD. However, previous data have been controversial. To investigate the relationship between IDE gene polymorphisms and LOAD risk, a case–control association study of 406 Han Chinese participants in Xinjiang, China, was undertaken. The LOAD and control groups consisted of 202 and 204 participants, respectively. The single-nucleotide polymorphisms rs1887922 and rs1999764 of the IDE ge...
Source: Journal of Geriatric Psychiatry and Neurology - April 28, 2015 Category: Genetics & Stem Cells Authors: Wang, S., He, F., Wang, Y. Tags: Articles Source Type: research

Common Polymorphisms in the GSK3{beta} Gene May Contribute to the Pathogenesis of Alzheimer Disease: A Meta-Analysis
Conclusion: Our findings suggest that there exists a significant association between GSK3β rs334558 T>C polymorphism and increased susceptibility of AD. Moreover, future updated studies with stratified case–control population are warranted for validation studies. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - April 28, 2015 Category: Genetics & Stem Cells Authors: Lin, Q., Cao, Y.-P., Gao, J. Tags: Articles Source Type: research

Incidence of Tardive Dyskinesia in Older Adult Patients Treated With Olanzapine or Conventional Antipsychotics
Conclusion: The cumulative incidence of persistent TD was low and the risk of persistent TD did not differ significantly among predominantly older adult patients having dementia with acute psychosis or agitation treated with OLZ or CNV. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Kinon, B. J., Kollack-Walker, S., Jeste, D., Gupta, S., Chen, L., Case, M., Chen, J., Stauffer, V. Tags: Articles Source Type: research

The Synergistic Effects of Anxiety and Cerebral Hypoperfusion on Cognitive Dysfunction in Older Adults With Cardiovascular Disease
Conclusions: Higher anxiety may exacerbate the effects of cerebral hypoperfusion on cognitive impairment. Longitudinal studies are needed to confirm our findings and determine whether anxiety treatment improves neurocognitive outcomes in CVD. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Alosco, M. L., Gunstad, J., Beard, C., Xu, X., Clark, U. S., Labbe, D. R., Jerskey, B. A., Ladino, M., Cote, D. M., Walsh, E. G., Poppas, A., Cohen, R. A., Sweet, L. H. Tags: Articles Source Type: research

Correlation Between Impulsivity and Executive Function in Patients With Parkinson Disease Experiencing Depression and Anxiety Symptoms
Conclusions: The present results suggest that depression and anxiety were highly correlated to impulsivity but not to executive functions changes in these PD patients. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Fonoff, F. C., Fonoff, E. T., Barbosa, E. R., Quaranta, T., Machado, R. B., de Andrade, D. C., Teixeira, M. J., Fuentes, D. Tags: Articles Source Type: research

Medial Temporal Lobe Atrophy and Depressive Symptoms in Elderly Patients With and Without Alzheimer Disease
Conclusion: Hippocampal atrophy was more pronounced among patients having SCI with depressive symptoms, while the medial temporal lobe was less atrophic in patients having AD with depressive symptoms than those without depressive symptoms. These findings suggest that different mechanisms underlie depression in older people with and without AD and may explain some of the inconsistent observations in previous studies. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Enache, D., Cavallin, L., Lindberg, O., Farahmand, B., Kramberger, M. G., Westman, E., Jelic, V., Eriksdotter, M., Ballard, C., Winblad, B., Wahlund, L.-O., Aarsland, D. Tags: Articles Source Type: research

Relationships Between Testosterone Levels and Cognition in Patients With Alzheimer Disease and Nondemented Elderly Men
Conclusion: Findings suggest that testosterone is not associated with most neuropsychological test performances in patients with AD. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Seidl, J. N. T., Massman, P. J. Tags: Articles Source Type: research

Direct and Indirect Assessments of Activities of Daily Living in Behavioral Variant Frontotemporal Dementia and Alzheimer Disease
Conclusion: Functional changes in bvFTD seem to be better documented by indirect measures. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Lima-Silva, T. B., Bahia, V. S., Carvalho, V. A., Guimaraes, H. C., Caramelli, P., Balthazar, M. L. F., Damasceno, B., Bottino, C. M. d. C., Brucki, S. M. D., Nitrini, R., Yassuda, M. S. Tags: Articles Source Type: research

Patterns and Predictors of Mental Health Service Utilization in People With Parkinson's Disease
Conclusion: This study highlights the integral role of the PD neurologist in facilitating awareness and treatment of mental health problems for individuals with PD. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Troeung, L., Gasson, N., Egan, S. J. Tags: Articles Source Type: research

Neuropsychological and Behavioral Disturbance Correlates of Unawareness of Memory Impairment in Dementia: A Population-Based Study
Conclusion: Different ways of measuring unawareness are differentially associated with influencing factors. Informant-based unawareness measures may be more subjective and less sensitive than variables taking into account actual performance on cognitive tests. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Mograbi, D. C., Ferri, C. P., Stewart, R., Sosa, A. L., Brown, R. G., Laks, J., Morris, R. G. Tags: Articles Source Type: research

Validation of the 10/66 Dementia Research Group Diagnostic Assessment for Dementia in Arabic: A Study in Lebanon
Conclusion: The 10/66 DRG diagnostic assessment for dementia is well suited for case ascertainment in epidemiological studies among Arabic-speaking older population with high prevalence of illiteracy. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - October 30, 2014 Category: Genetics & Stem Cells Authors: Phung, K. T. T., Chaaya, M., Waldemar, G., Atweh, S., Asmar, K., Ghusn, H., Karam, G., Sawaya, R., Khoury, R. M., Zeinaty, I., Salman, S., Hammoud, S., Radwan, W., Bassil, N., Prince, M. Tags: Articles Source Type: research

Do Subjective Memory Complaints Herald the Onset of Mild Cognitive Impairment in Parkinson Disease?
Discussion: This is the first prospective study to explore the relationship between subjective and objective cognitive deficits in newly diagnosed, untreated patients. Our results provide preliminary evidence that subjective memory complaints might predict future development of MCI. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - October 30, 2014 Category: Genetics & Stem Cells Authors: Erro, R., Santangelo, G., Barone, P., Picillo, M., Amboni, M., Longo, K., Giordano, F., Moccia, M., Allocca, R., Pellecchia, M. T., Vitale, C. Tags: Articles Source Type: research