Journal of Geriatric Psychiatry and Neurology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Symptom Assessment for a Palliative Care Approach in People With Dementia Admitted to Acute Hospitals: Results From a National Audit
Conclusion: This study suggests a picture of poor symptom assessment and possible inappropriate prescription of antipsychotic medication, including at EOL, hindering the planning and delivery of effective dementia palliative care in acute hospitals. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - October 26, 2015 Category: Genetics & Stem Cells Authors: O'Shea, E., Timmons, S., Kennelly, S., Siun, A. d., Gallagher, P., O'Neill, D. Tags: Articles Source Type: research

The Relationship Between Medial Temporal Lobe Atrophy and Cognitive Impairment in Patients With Dementia With Lewy Bodies
Conclusions: These results suggest that MTA is related to cognitive impairment in patients with DLB, particularly the regions of orientation, immediate and delayed recall, and word fluency. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - October 26, 2015 Category: Genetics & Stem Cells Authors: Tagawa, R., Hashimoto, H., Nakanishi, A., Kawarada, Y., Muramatsu, T., Matsuda, Y., Kataoka, K., Shimada, A., Uchida, K., Yoshida, A., Higashiyama, S., Kawabe, J., Kai, T., Shiomi, S., Mori, H., Inoue, K. Tags: Articles Source Type: research

Executive Abilities as Reflected by Clock Hand Placement: Frontotemporal Dementia Versus Early-Onset Alzheimer Disease
The clock-drawing test (CDT) is widely used in clinical practice to diagnose and distinguish patients with dementia. It remains unclear, however, whether the CDT can distinguish among the early-onset dementias. Accordingly, we examined the ability of both quantitative and qualitative CDT analyses to distinguish behavioral variant frontotemporal dementia (bvFTD) and early-onset Alzheimer disease (eAD), the 2 most common neurodegenerative dementias with onset <65 years of age. We hypothesized that executive aspects of the CDT would discriminate between these 2 disorders. The study compared 15 patients with bvFTD and 16 pa...
Source: Journal of Geriatric Psychiatry and Neurology - October 26, 2015 Category: Genetics & Stem Cells Authors: Barrows, R. J., Barsuglia, J., Paholpak, P., Eknoyan, D., Sabodash, V., Lee, G. J., Mendez, M. F. Tags: Articles Source Type: research

Comparison of Clock Test Deficits Between Elderly Patients With Early and Late Onset Depression
To compare clock test deficits in elderly patients with early onset depression (EOD) and late onset depression (LOD), we assessed 32 elderly healthy controls (HCs), 26 patients with EOD, and 27 patients with LOD with the clock drawing test (CDT), clock setting test, clock reading test, and the Tübingen Clock Questionnaire testing semantic memory about clock times. There was no significant difference in depression severity between patients with EOD and LOD. Patients with LOD had significantly lower scores on the CDT than patients with EOD and HCs. Semantic memory impairment concerning minute hand functionality was h...
Source: Journal of Geriatric Psychiatry and Neurology - October 26, 2015 Category: Genetics & Stem Cells Authors: Klein, L., Saur, R., Müller, S., Leyhe, T. Tags: Articles Source Type: research

The Role of Coping Strategies in Psychological Outcomes for Frontotemporal Dementia Caregivers
This study identifies variables amenable to clinical interventions that can improve caregivers’ well-being: specifically, caregiver strain and coping strategies. For a disease without cure yet increasing prevalence and cost, ameliorating the caregiver experience through targeted interventions is essential. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - August 20, 2015 Category: Genetics & Stem Cells Authors: Roche, DClinPsy, L., Croot, K., MacCann, C., Cramer, B., Diehl-Schmid, J. Tags: Articles Source Type: research

A Pilot Study of a Cognitive-Behavioral Treatment for Anxiety and Depression in Patients With Parkinson Disease
Anxiety and depression often remain unrecognized or inadequately treated in patients with Parkinson disease (PD). Cognitive–behavioral therapy (CBT) is effective, but limited evidence supports its use for anxiety and depression in patients with PD. Sixteen patients with PD having significant anxiety and/or depressive symptoms were assigned to CBT or enhanced usual care. Assessments occurred at baseline, posttreatment, and 1-month follow-up. The CBT intervention included tools for anxiety, depression, and healthy living with PD symptoms. Individual sessions were delivered by telephone or in person, based on patient pr...
Source: Journal of Geriatric Psychiatry and Neurology - August 20, 2015 Category: Genetics & Stem Cells Authors: Calleo, J. S., Amspoker, A. B., Sarwar, A. I., Kunik, M. E., Jankovic, J., Marsh, L., York, M., Stanley, M. A. Tags: Articles Source Type: research

Patient Mood and Instrumental Activities of Daily Living in Alzheimer Disease: Relationship Between Patient and Caregiver Reports
This retrospective study investigated the relationship between self-reports and caregiver perceptions of patients’ depressive symptoms and the respective ability of these reports to predict instrumental activities of daily living (IADLs) beyond what is accounted for by cognitive abilities in 71 patients with mild Alzheimer disease. Patients completed the Geriatric Depression Scale-Short Form, and caregivers completed the Behavior Rating Scale for Dementia assessing their perception of patients’ depressive symptoms. Caregivers also completed IADL items from the Alzheimer’s Disease Cooperative Study Activit...
Source: Journal of Geriatric Psychiatry and Neurology - August 20, 2015 Category: Genetics & Stem Cells Authors: Votruba, K. L., Persad, C., Giordani, B. Tags: Articles Source Type: research

AD8 Informant Questionnaire for Cognitive Impairment: Pragmatic Diagnostic Test Accuracy Study
In conclusion, AD8 is very sensitive for cognitive impairment in a memory clinic but specificity may be inadequate. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - August 20, 2015 Category: Genetics & Stem Cells Authors: Larner, A. J. Tags: Articles Source Type: research

The Modified Telephone Interview for Cognitive Status is More Predictive of Memory Abilities Than the Mini-Mental State Examination
Although not as popular as the Mini-Mental State Examination (MMSE), the modified Telephone Interview for Cognitive Status (mTICS) has some distinct advantages when screening cognitive functioning in older adults. The current study compared these 2 cognitive screening measures in their ability to predict performance on a memory composite (ie, delayed recall of verbal and visual information) in a cohort of 121 community-dwelling older adults, both at baseline and after 1 year. Both the MMSE and the mTICS significantly correlated with the memory composite at baseline (r’s of .41 and .62, respectively) and at 1 year (r&...
Source: Journal of Geriatric Psychiatry and Neurology - August 20, 2015 Category: Genetics & Stem Cells Authors: Duff, K., Tometich, D., Dennett, K. Tags: Articles Source Type: research

Functional Neuroanatomical Correlates of The Frontal Assessment Battery Performance in Alzheimer Disease: A FDG-PET Study
Conclusions: Although FAB scores are influenced by temporoparietal dysfunction due to the overall progression of AD, it likely reflects prefrontal dysfunction specifically regardless of global cognitive state or disease severity in patients with AD. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - August 20, 2015 Category: Genetics & Stem Cells Authors: Lee, J. H., Byun, M. S., Sohn, B. K., Choe, Y. M., Yi, D., Han, J. Y., Choi, H. J., Baek, H., Woo, J. I., Lee, D. Y. Tags: Articles Source Type: research

Mild Cognitive Impairment Subtypes in Older People With Depressive Symptoms: Relationship With Clinical Variables and Hippocampal Change
Conclusions: MCI occurs in older adults with a history of depression and is not simply due to symptom severity. Memory change is linked to underlying hippocampal atrophy in this patient group. (Source: Journal of Geriatric Psychiatry and Neurology)
Source: Journal of Geriatric Psychiatry and Neurology - August 20, 2015 Category: Genetics & Stem Cells Authors: Jayaweera, H. K., Hickie, I. B., Duffy, S. L., Hermens, D. F., Mowszowski, L., Diamond, K., Terpening, Z., Paradise, M., Lewis, S. J. G., Lagopoulos, J., Naismith, S. L. Tags: Articles Source Type: research

Apathy in Neurodegenerative Diseases: Recommendations on the Design of Clinical Trials
Apathy is a common feature of neurodegenerative disorders but is difficult to study in a clinical trial setting due to practical and conceptual barriers. Principal challenges include a paucity of data regarding apathy in these disorders, an absence of established diagnostic criteria, the presence of confounding factors (eg, coexisting depression), use of concomitant medications, and an absence of a gold-standard apathy assessment scale. Based on a literature search and ongoing collaboration among the authors, we present recommendations for the design of future clinical trials of apathy, suggesting Alzheimer disease and Par...
Source: Journal of Geriatric Psychiatry and Neurology - August 20, 2015 Category: Genetics & Stem Cells Authors: Cummings, J., Friedman, J. H., Garibaldi, G., Jones, M., Macfadden, W., Marsh, L., Robert, P. H. Tags: Articles Source Type: research

The Times They Are a-Changin': Clock Drawing and Prediction of Dementia
Identification of individuals who will eventually develop dementia is critical for early intervention, treatment, and care planning. The clock drawing test (CDT) is a widely used cognitive screening tool that has been well accepted among clinicians and patients for its ease of use and short administration time. This review explores the value of the CDT for predicting the later development of dementia in cognitively intact older adults and patients with mild cognitive impairment (MCI). Additionally, we reviewed studies that examined the ability of the CDT to monitor declines in cognitive functioning over time. A PubMed lite...
Source: Journal of Geriatric Psychiatry and Neurology - April 28, 2015 Category: Genetics & Stem Cells Authors: Amodeo, S., Mainland, B. J., Herrmann, N., Shulman, K. I. Tags: Articles Source Type: research

The Neuropsychiatric Profile of Posterior Cortical Atrophy
We analyzed scores obtained at the Neuropsychiatric Inventory (NPI) by 20 patients with posterior cortical atrophy (PCA) and contrasted it with 20 patients having Alzheimer disease (AD). Patients with hallucinations and delusions were not included due to the high probability of a diagnosis of Lewy body disease. Prevalence of behavioral and psychological symptoms (BPSD) was 95% in the PCA group, the most frequent being apathy and anxiety. Cluster analysis on NPI subscales highlighted a behavioral subsyndrome characterized by agitated temper and irritability. Depression, anxiety, and apathy did not cluster with any other BPS...
Source: Journal of Geriatric Psychiatry and Neurology - April 28, 2015 Category: Genetics & Stem Cells Authors: Isella, V., Villa, G., Mapelli, C., Ferri, F., Appollonio, I. M., Ferrarese, C. Tags: Articles Source Type: research

Risk of Dementia in Older Adults With Low Versus High Occupation-Based Motivational Processes: Differential Impact of Frequency and Proximity of Social Network
This study investigates the impact of occupation-based motivational processes and social network variables on the incidence of dementia over 8 years. Method: Data were derived from the Leipzig Longitudinal Study of the Aged (LEILA75+), a population-based longitudinal study of individuals aged 75 years and older (n = 1692 at baseline). Motivational processes were estimated based on the main occupation using the Occupational Information Network database. Results: In a Cox proportional hazard model, motivational processes were not associated with the risk of dementia (hazard ratio [HR]: 0.93, 95% confidence interval [CI]: 0...
Source: Journal of Geriatric Psychiatry and Neurology - April 28, 2015 Category: Genetics & Stem Cells Authors: Fankhauser, S., Forstmeier, S., Maercker, A., Luppa, M., Luck, T., Riedel-Heller, S. G. Tags: Articles Source Type: research