Medial Temporal Lobe Atrophy and Depressive Symptoms in Elderly Patients With and Without Alzheimer Disease

Conclusion:
Hippocampal atrophy was more pronounced among patients having SCI with depressive symptoms, while the medial temporal lobe was less atrophic in patients having AD with depressive symptoms than those without depressive symptoms. These findings suggest that different mechanisms underlie depression in older people with and without AD and may explain some of the inconsistent observations in previous studies.

Source: Journal of Geriatric Psychiatry and Neurology - February 5, 2015 Category: Genetics & Stem Cells Authors: Enache, D., Cavallin, L., Lindberg, O., Farahmand, B., Kramberger, M. G., Westman, E., Jelic, V., Eriksdotter, M., Ballard, C., Winblad, B., Wahlund, L.-O., Aarsland, D. Tags: Articles Source Type: research