The Risk of Glaucoma and Serotonergic Antidepressants: a Systematic Review and Meta-analysis
The glaucoma comprise a heterogeneous group of optic neuropathies characterized by progressive degeneration of retinal ganglion cells that may result in a progressive loss of visual sensitivity, and in some patients, blindness. The hallmark of this group of diseases is optic disc excavation (often referred to as cupping), a characteristic deformation and remodeling of the optic nerve head in response to intraocular pressure (IOP)-related biomechanical stress that can occur at any level of IOP. Primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) are the most frequently types of glaucomatous disease....
Source: Journal of Affective Disorders - August 1, 2018 Category: Neurology Authors: Hung-Yu Wang, Ping-Tao Tseng, Brendon Stubbs, Andre F. Carvalho, Dian-Jeng Li, Tien-Yu Chen, Pao-Yen Lin, Yu-Te Hsueh, Yu-Zhen Chen, Yen-Wen Chen, Che-Sheng Chu Source Type: research
Prevalence of major depressive disorder in children and adolescents in China: a systematic review and meta-analysis
Depression, a leading cause of global disease burden, often begins in adolescence (Avenevoli et al., 2015; Hankin, et al., 1998). Over half of individuals who experienced depression in adolescence have at least one recurrence in adulthood (Hankin et al., 1998; Rutter et al., 2006). Adolescent depression has negative outcomes, such as poor educational achievement, social impairment, insomnia, smoking and substance abuse (Buysse et al., 2008; Fergusson& Woodward, 2002; Lewinsohn et al., 1998). Moreover, depression is a major risk factor for suicide, contributing to the second most common cause of death in adolescents (World ...
Source: Journal of Affective Disorders - August 1, 2018 Category: Neurology Authors: Dan Xu, Wen-Wang Rao, Xiao-Lan Cao, Si-Ying Wen, Weng-Ian Che, Chee H. Ng, Gabor S. Ungvari, Yasong Du, Ling Zhang, Yu-Tao Xiang Tags: Research paper Source Type: research
Latent Trajectory Classes of Postpartum Depressive Symptoms: A Regional Population-Based Longitudinal Study
Postpartum depression (PPD) affects 10 –15% of women (Gavin et al., 2005; O'Hara and Swain, 1996). Symptoms of PPD usually peak at 4 to 6 weeks and, thereafter, gradually decline from 3 months and towards the end of the first year postpartum (Haga et al., 2012; Vliegen et al., 2014). In most studies, it is assumed that participants com e from one single, homogenous population that follow the same trajectories in symptomatology over time (see e.g., Horwitz et al., 2009; Seto et al., 2005; Wang et al., 2011; Woolhouse et al., 2015). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - August 1, 2018 Category: Neurology Authors: Filip Drozd, Silje Marie Haga, Lisbeth Valla, Kari Slinning Tags: Original Research Paper Source Type: research
Lifetime affective problems and later-life cognitive state: over 50 years of follow-up in a British Birth Cohort Study
Many studies have demonstrated an association between depression and anxiety – affective symptoms - and subsequent cognitive impairment and dementia (Cherbuin et al., 2015; da Silva et al., 2013; Gulpers et al., 2016; John et al., 2018; Jorm, 2001; Ownby et al., 2006; Stella et al., 2014). The severity, frequency and onset of symptoms are thought to be important features i n establishing the nature of these associations (Bennett and Thomas, 2014; Byers and Yaffe, 2011; da Silva et al., 2013; Kaup et al., 2016; Köhler et al., 2010; Richards et al., 2014; Singh-Manoux et al., 2017), and feasibly affect cognitive function ...
Source: Journal of Affective Disorders - July 30, 2018 Category: Neurology Authors: Sarah-Naomi James, Daniel Davis, Celia O'Hare, Nikhil Sharma, Amber John, Darya Gaysina, Rebecca Hardy, Diana Kuh, Marcus Richards Tags: Research paper Source Type: research
Characterizing the Course of Suicidal Ideation Response to Ketamine
Suicide poses a serious threat to public health. Worldwide, suicide accounts for approximately 1 million deaths, and 10 million suicide attempts are reported annually (World Health Organization, 2014). In the United States, the national suicide rate has increased by approximately 28% over the last 15 years (Curtin et al., 2016). At the same time, relatively few interventions for suicide risk exist. While treatments such as clozapine and lithium have demonstrated effects on suicidal behavior over weeks to months, these effects may be limited to specific diagnoses (Cipriani et al., 2005; Griffiths et al., 2014). (Source: Jou...
Source: Journal of Affective Disorders - July 30, 2018 Category: Neurology Authors: Elizabeth D. Ballard, Julia S. Yarrington, Cristan A. Farmer, Erica Richards, Rodrigo Machado-Vieira, Bashkim Kadriu, Mark J. Niciu, Peixiong Yuan, Lawrence Park, Carlos A. Zarate Tags: Research paper Source Type: research
Cognitive function of patients with treatment-resistant depression after a single low dose of ketamine infusion
The sequenced treatment alternatives to relieve depression (STAR*D) study reported that up to 40% of patients with major depressive disorder did not achieve symptomatic remission after two trials of traditional antidepressants, which is defined as treatment-resistant depression (TRD). Approximately one-third of patients continued to experience depression after four trials of different antidepressant treatments, including combination therapy and augmentation therapy (Howland, 2008). TRD was commonly coupled with functional impairment, poor quality of life, suicide ideation and attempts, self-injurious behavior, and a high r...
Source: Journal of Affective Disorders - July 27, 2018 Category: Neurology Authors: Mu-Hong Chen, Cheng-Ta Li, Wei-Chen Lin, Chen-Jee Hong, Pei-Chi Tu, Ya-Mei Bai, Chih-Ming Cheng, Tung-Ping Su Tags: Research paper Source Type: research
Omega-3 Polyunsaturated Fatty Acids and Reduction of Depressive Symptoms in Older Adults: A Systematic Review and Meta-Analysis
Depression is a common psychiatric disorder significantly affecting more than 350 million people of all ages worldwide (Marcus et al., 2012). Depressive symptoms include feelings of sadness or hopelessness, loss of interest in most normal activities, change in appetite, sleep disturbances, tiredness and lack of energy, feelings of worthlessness or guilt, trouble concentrating, and suicidal ideation (Marcus et al., 2012). According to the Global Burden of Disease Study 2010 (Ferrari et al., 2014), mental and substance use disorders cause two thirds of all disability-adjusted life years allocated to suicide. (Source: Journal...
Source: Journal of Affective Disorders - July 27, 2018 Category: Neurology Authors: Zheng-Gang Bai, Ai Bo, Si-Jie Wu, Qiong-Yan Gai, Iris Chi Tags: Review article Source Type: research
Examining components of emotion regulation in relation to sleep problems and suicide risk
(Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 27, 2018 Category: Neurology Authors: Erin F. Ward-Ciesielski, E. Samuel Winer, Christopher W. Drapeau, Michael R. Nadorff Tags: Research paper Source Type: research
Ketamine Augmentation for Major Depressive Disorder and Suicidal Ideation: Preliminary Experience in an Inpatient Psychiatry Setting
There is a growing body of evidence demonstrating that intravenous ketamine infusions can provide rapid relief of depressive symptoms in people suffering from treatment-resistant major depressive disorder (MDD) as well as bipolar depression with various studies showing rapid response to a single infusion which persists for at least 72 hours (Aan Het Rot et al. 2012; DiazGranados et al. 2010; George et al. 2017; Ibrahim et al. 2011; Mathew et al. 2012; Murrough et al. 2013a; Singh et al. 2016; Su et al. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 27, 2018 Category: Neurology Authors: Mark Sinyor, Marissa Williams, Sue Belo, Beverley Orser, Margaret Vincent, Linda Mah, Carlos Zarate, Saulo Castel, Anthony J. Levitt, Ayal Schaffer Tags: Research paper Source Type: research
The association between motives, perceived problems and current thoughts of self-harm following an episode of self-harm. A network analysis
Suicidal behaviour is an important global health problem, with an estimated 800.000 suicides per year (World Health Organisation, 2014). The majority of individuals who die by suicide have a history of self-harm (Cooper et al., 2005; Owens et al., 2002 Hawton and van Heeringen, 2009; O'Connor and Nock, 2014). Patients who are referred to emergency departments following self-harm are therefore at a high risk of repeat suicidal behaviour, and require psychiatric evaluation and follow up interventions. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 27, 2018 Category: Neurology Authors: Derek de Beurs, Nikita Vancayseele, Claudia van Borkulo, Gwendolyn Portzky, Kees van Heeringen Tags: Research paper Source Type: research
From ideation to action: differentiating between those who think about suicide and those who attempt suicide in a national study of young adults
Suicide is a global health problem, and although suicide affects people across the lifespan, it is the second leading cause of death of 16-29 year olds worldwide (World Health Organisation, 2014), as well as being the leading cause of death among people under 50 in the UK (Samaritans, 2017). Recent research has identified a wide range of social, psychological and biological factors that act to increase suicide risk (O'Connor and Nock, 2014), although these fac tors often do not distinguish between those who will think about suicide and those who will go on to act on suicidal thoughts (Klonsky and May, 2014). (Source...
Source: Journal of Affective Disorders - July 27, 2018 Category: Neurology Authors: Karen Wetherall, Seonaid Cleare, Sarah Eschle, Eamonn Ferguson, Daryl B. O'Connor, Ronan E. O'Carroll, Rory C. O'Connor Tags: Research paper Source Type: research
Prevalence of major depressive disorder in older adults in China: a systematic review and meta-analysis
Aging population is growing fast worldwide, especially in developing countries (Petersen and Yamamoto, 2005), such as in China. The proportion of the global population aged 60 years and above was projected to increase from 10.0% in 2000 to 21.8% in 2050 and to 32.2% in 2100 (Lutz et al., 2008). Due to the increased life expectancy and the previous one-child family policy, China's l arge population is rapidly aging with the proportion of older adults predicted to increase to 336 million in 2030 (Flaherty et al., 2007). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 26, 2018 Category: Neurology Authors: Fei Wang, Qing-E Zhang, Ling Zhang, Chee H. Ng, Gabor S. Ungvari, Zhen Yuan, June Zhang, Ling Zhang, Yu-Tao Xiang Tags: Research Paper Source Type: research
Cortical thickness reductions in the middle frontal cortex in patients with panic disorder
Panic disorder (PD) is an anxiety disorder which is characterized by the recurrence of cued and uncued panic attacks. Its typical course is chronic. Previous epidemiological studies have revealed that PD can lead to social dysfunction and lower quality of life, both of which have been shown to track with symptom severity (Kim et al., 2017; Ormel et al., 1994). PD has also been found to be associated with increased mortality and higher rate of suicide. It is, thus, important to elucidate neurobiological basis of social dysfunction in patients with PD. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - July 26, 2018 Category: Neurology Authors: Takeshi Asami, Masao Takaishi, Ryota Nakamura, Haruhisa Yoshida, Asuka Yoshimi, Thomas J. Whitford, Tomio Inoue, Yoshio Hirayasu Source Type: research
Loss experiences in old age and their impact on the social network and depression – Results of the Leipzig Longitudinal Study of the Aged (LEILA 75+)
Between 1990 and 2014, the number of people aged 65 years and older in Germany increased from 5.2 to 17.1 million (43%) (Haustein et al., 2016). The demographic trend and increasing longevity poses a considerable challenge to the healthcare system (Robert Koch-Institut, 2015). Depressive disorders belong to the most common mental disorders in old age after dementia (Schwarzbach et al., 2013; Riedel-Heller and Luppa, 2014) . Depression in old age can have major personal and public health consequences, so it is important to identify the factors that predict onset (Noteboom et al., 2016; Khow and Yu, 2017; Maske et al....
Source: Journal of Affective Disorders - July 26, 2018 Category: Neurology Authors: Franziska F örster, Janine Stein, Margrit Löbner, Alexander Pabst, Matthias C. Angermeyer, Hans-Helmut König, Steffi G. Riedel-Heller Tags: Research paper Source Type: research
Early weight gain predicts later weight gain in depressed patients treated with antidepressants: findings from the METADAP cohort
Major Depressive Disorder (MDD) is among the diseases that has the greatest impact worldwide on public health (Vigo et al., 2016). It confers a 50% increased mortality of somatic causes (Vos et al., 2012). Antidepressant drugs are the main treatment for Major Depressive Episodes (MDE) in patients with MDD even though antidepressants (AD) use – even newer generations - can induce weight gain (Carvalho et al., 2016). A recent cross- sectional survey without control group on 362 psychiatric patients taking AD for a period ranging from 6 to 36 months found that citalopram, escitalopram, sertraline, paroxetine, venlafaxine, d...
Source: Journal of Affective Disorders - July 25, 2018 Category: Neurology Authors: Khalil El Asmar, Bruno F ève, Romain Colle, Florence Gressier, Albane Vievard, Séverine Trabado, Céline Verstuyft, Emmanuel Haffen, Mircea Polosan, Florian Ferreri, Bruno Falissard, Philippe Chanson, Laurent Becquemont, Emmanuelle Corruble Source Type: research
