The burden of depression in systemic sclerosis patients: a nationwide population-based study
Systemic sclerosis (SSc) is an autoimmune connective-tissue disorder characterized by micro-vascular damage, immunologic impairments and tissue fibrosis, due to a massive deposition of collagen and other matrix substances within the skin and internal organs (Elhai et al., 2015). According to a large, population-wide assessment of two claim databases, in the USA, SSc has a prevalence of 0.05% (Robinson et al., 2008). Immune-mediated inflammatory diseases including SSc have a substantial societal burden, owing to the impacts of chronicity, acute exacerbati ons and progressive disability (Enns et al., 2018). (Source: J...
Source: Journal of Affective Disorders - September 21, 2018 Category: Neurology Authors: Nicola L. Bragazzi, Abdulla Watad, Alex Gizunterman, Dennis McGonagle, Hussein Mahagna, Doron Comaneshter, Howard Amital, Arnon D. Cohen, Daniela Amital Tags: Research paper Source Type: research
The association of vision loss and dimensions of depression over 12 years in older adults: findings from the Three City Study
Vision impairment (VI) is common in older adults, with an estimated prevalence of 25% in those aged over 70 (Stevens et al., 2013); and VI substantially contributes to burden of disease in Europe (Mathers& Loncar, 2006). An association between VI and depression in the elderly population is well established (Carriere et al., 2013; Court, McLean, Guthrie, Mercer,& Smith, 2014; Hong et al., 2015), with prevalence of comorbid depression in older adults with VI estimated to be around 30% (Hayman et al., 2007; Hong et al., 2015). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 21, 2018 Category: Neurology Authors: S Cosh, I Carriere, V Nael, C Tzourio, C Delcourt, C Helmer, the Sense-Cog Consortium ¥ Tags: Research paper Source Type: research
nSymptoms of Social Anxiety Disorder and Major Depressive Disorder: A Network Perspective
Social anxiety disorder (SAD) and major depressive disorder (MDD) are among the most prevalent disorders worldwide (Kessler, Berglund, et al., 2005), and investigators have documented their high rate of comorbidity (Beesdo et al., 2007; Brown et al., 2001; Kessler, Chiu et al., 2005; Ohayon& Schatzberg, 2010; Stein et al., 2001)1. Further, these disorders have been found to be associated with greater impairment when they co-occur than when either occurs alone (Norton et al., 2008). Despite these findings, however, we have only a limited understanding of the nature of the comorbidity of these disorders (Langer& Rodebaugh, 2...
Source: Journal of Affective Disorders - September 21, 2018 Category: Neurology Authors: Julia K. Langer, Natasha A. Tonge, Marilyn Piccirillo, Thomas L. Rodebaugh, Renee J. Thompson Source Type: research
GxE effects of FKBP5 and traumatic life events on PTSD: A meta-analysis
Recent findings from the World Mental Health Survey Consortium confirm that traumatic events are common, with over 70% of individuals endorsing at least one lifetime traumatic event and approximately one third endorsing four or more traumatic events (Benjet et al., 2016). Among a national sample of U.S. adults, 89.7% were exposed to at least one traumatic event, with 8.3% of exposed individuals reporting posttraumatic stress disorder (PTSD) during their lifetime (Kilpatrick et al., 2013). PTSD increases risk for a number of significant deleterious psychological (e.g., depression, substance use disorders, anxiety; Sareen et...
Source: Journal of Affective Disorders - September 21, 2018 Category: Neurology Authors: Sage E. Hawn, Christina M. Sheerin, Mackenzie J. Lind, Terrell A. Hicks, Marisa E. Marraccini, Kaitlin Bountress, Silviu-Alin Bacanu, Nicole R. Nugent, Ananda B. Amstadter Source Type: research
Abnormal cerebellum-DMN regions connectivity in unmedicated bipolar II disorder
Bipolar disorder (BD), a severe, chronic psychiatric disease, is a leading cause of disability, morbidity, and mortality from suicide, and is associated with several medical conditions, such as cardiovascular disease, diabetes mellitus, and neurovascular disease (Merikangas et al., 2007; Prieto et al., 2014). It is characterized by episodes of depression, mania (BD I), and hypomania (BD II) that seriously affect the social functioning and quality of life of patients (Dean et al., 2004; Merikangas et al., 2007). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 21, 2018 Category: Neurology Authors: Guanmao Chen, Lianping Zhao, Yanbin Jia, Shuming Zhong, Feng Chen, Xiaomei Luo, Shaojuan Qiu, Shunkai Lai, Zhangzhang Qi, Li Huang, Ying Wang Tags: Research paper Source Type: research
A randomized controlled trial of ‘MUMentum Pregnancy’: Internet-delivered cognitive behavioral therapy program for antenatal anxiety and depression
During pregnancy, approximately one in five women experience clinically significant symptoms of anxiety and depression, and one in six meet diagnostic criteria for an anxiety and/or major depressive disorder (MDD; Becker, Weinberger, Chandy and Schmukler, 2016; Dennis, Falah-Hassani and Shiri, 2017). Antenatal anxiety and depression are robust predictors of postpartum depression (Austin, Tully and Parker, 2007; Milgrom et al., 2008), and if left untreated, are associated with a range of adverse outcomes for both the mother and infant (e.g., reduced antenatal care; increased risk of preterm birth, low birth weight, and late...
Source: Journal of Affective Disorders - September 21, 2018 Category: Neurology Authors: Siobhan A. Loughnan, Amanda Sie, Megan J. Hobbs, Amy E. Joubert, Jessica Smith, Hila Haskelberg, Alison E.J. Mahoney, Natalie Kladnitski, Christopher J. Holt, Jeannette Milgrom, Marie-Paule Austin, Gavin Andrews, Jill M Newby Tags: Research paper Source Type: research
The burden of depression in systemic sclerosis patients: insights from a real-world big data-based analysis
Systemic sclerosis (SSc) is an autoimmune connective-tissue disorder characterized by micro-vascular damage, immunologic impairments and tissue fibrosis, due to a massive deposition of collagen and other matrix substances within the skin and internal organs (Elhai et al., 2015). According to a large, population-wide assessment of two claim databases, in the USA, SSc has a prevalence of 0.05% (Robinson et al., 2008). Immune-mediated inflammatory diseases including SSc have a substantial societal burden, owing to the impacts of chronicity, acute exacerbations and progressive disability (Enns et al., 2018). (Source: Journal o...
Source: Journal of Affective Disorders - September 21, 2018 Category: Neurology Authors: Nicola L. Bragazzi, Abdulla Watad, Alexander Gizunterman, Dennis McGonagle, Hussein Mahagna, Doron Comaneshter, Howard Amital, Arnon D. Cohen, Daniela Amital Tags: Research paper Source Type: research
Editorial Board
(Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 20, 2018 Category: Neurology Source Type: research
Relations between Trait Anxiety and Depression: A Mediated Moderation Model
Trait anxiety reflects an individual's predisposition to worry and anxiety when facing dangerous or uncertain situations. In recent years, studies in cognitive neuroscience have suggested that high trait anxiety is an important vulnerable phenotype for stress-induced depression (Weger and Sandi, 2018). Individuals with high anxiety traits not only are more susceptible to stress but also have specific neurocognitive characteristics (Sandi and Richter-Levin, 2009). In the management of threats or ambiguous situations, people with high trait anxiety have a unique cognitive style. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 20, 2018 Category: Neurology Authors: Tao Wang, Min Li, Song Xu, Botao Liu, Tong Wu, Fang Lu, Junpeng Xie, Li Peng, Jia Wang Tags: Research paper Source Type: research
Seasonality in Bipolar Disorder: Effect of Sex and Age
Mood episodes in bipolar disorder (BD) are found to exhibit a seasonal pattern (SP), with peaks for manic episodes in spring-summer and peaks for depressive episodes in early winter (Geoffroy et al., 2014; Lee et al., 2007; Volpe et al., 2010; Medici et al., 2016; Parker et al., 2017). Mixed episodes are most often described to peak in early spring and summer (Cassidy and Carroll, 2002; Lee et al., 2007; Whitney et al., 1999; Yang et al., 2013). These patterns have been observed in countries of the northern as well as the southern hemisphere, however, rarely in equatorial regions (Medici et al., 2016). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 20, 2018 Category: Neurology Authors: Matth äus Fellinger, Thomas Waldhoer, Daniel König, Barbara Hinterbuchinger, Nathalie Pruckner, Josef Baumgartner, Sandra Vyssoki, Benjamin Vyssoki Tags: Research paper Source Type: research
Quality of life across domains among individuals with treatment-resistant depression
Depression is a common, debilitating illness that often fails to respond to first- and second-line treatments. For example, about one-third of patients did not reach remission after multiple optimized pharmacologic trials during the STAR-D study (Rush et al., 2006). Recent estimates for treatment resistant depression (TRD), often defined by two or more treatment failures, indicate a 12-month prevalence rate of approximately 2% in the US (Nemeroff, 2007). Furthermore, long-term outcomes of TRD are typically very poor. (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 19, 2018 Category: Neurology Authors: Heidemarie Lex, Yarden Ginsburg, Adam F. Sitzmann, Clara Grayhack, Daniel F. Maixner, Brian J. Mickey Tags: Research paper Source Type: research
Associations between broader autism phenotype (BAP) and maternal attachment are moderated by maternal postpartum depression when infants are one month old: A prospective study of the Japan Environment & Children's Study
Recently, broader autism phenotype (BAP) has been the focus of research studies. BAP refers to the expression of behavioral and cognitive dispositions similar to autism spectrum disorders, but at subthreshold levels (Asano et al., 2014; Dawson et al., 2007). Previous studies revealed that individuals with BAP had deficits in social motivation and communication; impairments in facial processing and executive functioning; and lower levels of motor imitation and language (Asano et al., 2014; Dawson et al., 2002; 2005; Piven et al., 1997; Sucksmith, et al., 2011). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 19, 2018 Category: Neurology Authors: Kumi Hirokawa, Takashi Kimura, Satoyo Ikehara, Kaori Honjo, Takuyo Sato, Kimiko Ueda, Hiroyasu Iso, Japan Environment & Children's Study Group Tags: Research paper Source Type: research
The prevalence of depressive symptoms in ‘left-behind children’ in China: a meta-analysis of comparative studies and epidemiological surveys
Due to the unprecedented increase in internal migration of workers in China, a unique and widespread social phenomenon of the so-called ‘left-behind children’ (LBC) has emerged (He et al., 2012). The phenomenon of LBC refers to children who are left at home for at least 6 months while one or both parents move elsewhere to work (Duan& Zhou, 2005). The rapid economic development in China has shifted a massive workforce from rural to urban areas in recent decades (Wen& Lin, 2012). Due to the financial and social welfare constraints in urban settings, it is common for migrant workers to leave their children behind in...
Source: Journal of Affective Disorders - September 18, 2018 Category: Neurology Authors: Yuan-Yuan Wang, Le Xiao, Wen-Wang Rao, Jing-Xin Chai, Shu-Fang Zhang, Chee H. Ng, Gabor S. Ungvari, Huiping Zhu, Yu-Tao Xiang Tags: Research paper Source Type: research
Bipolar Disorder and Psychotropic Medication: Impact on Pregnancy and Neonatal Outcomes
Bipolar disorder (BD) is a serious psychiatric condition that affects 1% to 2% of people in the United States. Inclusion of the more broadly defined bipolar spectrum disorders raises the prevalence to between 3% and 6.5% (Angst, 1998). The median age of onset of BD is during late adolescence (19.4 years in the Stanley Foundation Bipolar Network) (Post et al., 2003); therefore, women are at risk for episodes during their childbearing years. Forty to 70% of women with BD will suffer recurrent episodes post-birth (Reich an d Winokur, 1970, van Gent and Verhoeven, 1992, Wisner et al., 2004). (Source: Journal of Affective Disorders)
Source: Journal of Affective Disorders - September 18, 2018 Category: Neurology Authors: Katherine L. Wisner, Dorothy Sit, Kelly O'Shea, Debra L. Bogen, Crystal T. Clark, Emily Pinheiro, Amy Yang, Jody D. Ciolino Tags: Research paper Source Type: research
Nonlinear dynamics of mood regulation in unaffected first-degree relatives of bipolar disorder patients
Evidence from family, twin and adoption studies indicates a heritable component to bipolar disorder (Craddock and Jones, 1999). Because unaffected relatives share a proportion of the genetic material with the patient, abnormalities found in unaffected relatives may reflect trait-related neurobiological markers of the illness. In this sense, similar structural (Chaddock et al., 2009; McDonald et al., 20 04; van der Schot et al., 2009) and functional (Antila et al., 2007; Drapier et al., 2008; Schulze et al., 2011; Surguladze et al., 2010; Thermenos et al., 2010; Zalla et al., 2004) abnormalities in both unaffect...
Source: Journal of Affective Disorders - September 18, 2018 Category: Neurology Authors: Ortiz A, Bradler K, Garnham J, Slaney C, McLean S, Alda M Tags: Research paper Source Type: research
