Japanese Journal of Clinical Oncology This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Clinical approach to re-irradiation for recurrent diffuse intrinsic pontine glioma
ConclusionsHigher doses of re-irradiation based on a clinical-response-based approach show improvement in survival and steroid dependence rates with acceptable toxicity. Steroid independent status at 1-month post-re-irradiation predicts better outcomes. Prospective studies may validate this with quality of life data. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 30, 2021 Category: Cancer & Oncology Source Type: research

Medical costs of lung cancer care in Japan during the first one or two years after initial diagnosis
ConclusionsIn NSCLC patients, medical costs increased with prolonged survival during the last decade. The costs on a monthly basis did not change. The proportion of outpatient costs increased. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 28, 2021 Category: Cancer & Oncology Source Type: research

Medical costs of Japanese lung cancer patients during end-of-life care
ConclusionsThe medical costs during the end-of-life period for lung cancer were high and surpassed those for initial treatment. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 28, 2021 Category: Cancer & Oncology Source Type: research

Surgical challenges in multimodal treatment of N2-stage IIIA non-small cell lung cancer
AbstractLocally advanced non-small cell lung cancer, especially mediastinal lymph node metastasis-positive stage IIIA-N2 cancer, is a heterogeneous disease state characterized by anatomically locally advanced disease with latent micrometastases. Thus, surgical resection or radiotherapy alone has historically failed to cure this disease. During the last three decades, persistent efforts have been made to develop a suitable treatment modality to overcome these problems using chemotherapy and/or radiotherapy with surgical resection. However, the role of surgical resection remains unclear, and the standard treatment for stage ...
Source: Japanese Journal of Clinical Oncology - January 28, 2021 Category: Cancer & Oncology Source Type: research

Age-specific incidence rates of gallbladder cancer in the world
In order to make a comparison of the age-specific cancer incidence rate of gallbladder and other parts of biliary tract (hereinafter, referred to as gallbladder cancer) between Japan and other countries, we abstracted cancer incidence rate from the Cancer Incidence in Five Continents Vol. XI (CI5) (1). The International Agency for Research on Cancer provides the CI5 databases on the incidence of cancer recorded by cancer registries (regional and national) worldwide. We used cancer incidence rate in five countries in Asia (China, India, Japan, Republic of Korea and Thailand), three countries in America (USA, Canada and Braz...
Source: Japanese Journal of Clinical Oncology - January 28, 2021 Category: Cancer & Oncology Source Type: research

Prognostic impact of geriatric assessment in elderly patients with non-small cell lung cancer: an integrated analysis of two randomized phase III trials (JCOG1115-A)
ConclusionMMSE scores, performance status and sex, but not chronological age, effectively predicted the prognosis of elderly patients. Further studies should confirm that the Mini-Mental State Examination is useful for determining the indication of chemotherapy in elderly patients with advanced non-small cell lung cancer. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 22, 2021 Category: Cancer & Oncology Source Type: research

External validation of the albumin, C-reactive protein and lactate dehydrogenase model in patients with metastatic renal cell carcinoma receiving second-line axitinib therapy in a Japanese multi-center cohort
ConclusionsThe utility of the albumin, C-reactive protein and lactate dehydrogenase model as a simple and objective prognostication tool was successfully validated using data from 421 metastatic renal cell carcinoma patients receiving second-line axitinib. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 22, 2021 Category: Cancer & Oncology Source Type: research

Possibilities for and limits of upfront surgical strategy with lateral pelvic node dissection for low rectal cancer
ConclusionsMetastatic lateral pelvic nodes had no impact on cumulative risks of local recurrence and recurrence-free survival based on an upfront lateral pelvic nodes strategy. Lateral pelvic nodes can improve recurrence and survival outcomes in locally advanced low rectal cancer patients with metastatic lateral pelvic nodes. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 22, 2021 Category: Cancer & Oncology Source Type: research

The impact of body composition on short-term outcomes of neoadjuvant chemotherapy with gemcitabine plus S-1 in patients with resectable pancreatic cancer
ConclusionsIn our experience, NAC GS was similarly tolerable and effective in resectable pancreatic cancer patients regardless of the presence of sarcopenia. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 22, 2021 Category: Cancer & Oncology Source Type: research

Response to the Dr Shikata ’s letter: ‘Secondhand smoke exposure and risk of lung cancer in Japan: a systematic review and meta-analysis of epidemiologic studies’
(Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 18, 2021 Category: Cancer & Oncology Source Type: research

Therapeutic benefit of lymphadenectomy for older patients with urothelial carcinoma of the upper urinary tract: a propensity score matching study
ConclusionsThis study suggests that complete-lymphadenectomy may provide therapeutic benefits for older patients. The decision to perform complete-lymphadenectomy must be based on the patient ’s physical condition, rather than his/her chronological age. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 13, 2021 Category: Cancer & Oncology Source Type: research

Post-marketing surveillance study of trifluridine/tipiracil in patients with metastatic colorectal cancer
ConclusionThis post-marketing surveillance study further confirmed the safety and tolerability profile of trifluridine/tipiracil observed in a clinical study setting. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 13, 2021 Category: Cancer & Oncology Source Type: research

Surgical outcomes of primary lung cancers following esophagectomy for primary esophageal carcinoma
ConclusionsPulmonary resection for primary lung cancers following esophagectomy for esophageal carcinoma is acceptable in selected patients. Such surgery requires caution concerning intrathoracic adhesions and postoperative prolonged air leakage. Patients with restrictive ventilatory impairment had a poorer prognosis, and the indication for surgery in these patients should be carefully considered. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 13, 2021 Category: Cancer & Oncology Source Type: research

Establishing an endoscopic diagnostic process system (M-system) for gastric MALT lymphoma of superficial-spreading type
ConclusionsThe M-system can improve the diagnostic accuracy of mucosa-associated lymphoid tissue lymphoma of the superficial-spreading type on detailed magnifying endoscopy. This would help in the early diagnosis of the disease and treatment, which would translate into improved clinical outcomes. (Source: Japanese Journal of Clinical Oncology)
Source: Japanese Journal of Clinical Oncology - January 13, 2021 Category: Cancer & Oncology Source Type: research

Prospective observational study estimating willingness-to-pay for breast cancer treatments through contingent valuation method in Japanese breast cancer patients (JCOG1709A)
This study investigates how Japanese breast cancer patients who received treatment in Japan consider the financial value (willingness-to-pay; WTP) for their life and health by using the contingent valuation method (CVM) prospectively. First, 168 patients (84 primary breast cancer patients and 84 metastatic breast cancer patients) were pre-examined their WTP with dichotomous-choice method survey form. Next, 1,596 patients (798 primary breast cancer patients and 798 metastatic breast cancer patients) will be surveyed to their WTP for hypothetical scenarios in CVM. Based on our results, we will construct an evaluation axis fr...
Source: Japanese Journal of Clinical Oncology - January 13, 2021 Category: Cancer & Oncology Source Type: research