Symposium: Imaging modalities for drug-related osteonecrosis of the jaw (1), role of imaging in drug-related osteonecrosis of the jaw: An up-to-date review (secondary publication)
Publication date: November 2019Source: Japanese Dental Science Review, Volume 55, Issue 1Author(s): Makoto Tsuchimochi, Tohru KurabayashiSummaryMRONJ/ARONJ is a serious adverse effect of medication, although the incidence of the disease is rare, and there are still controversial issues regarding the pathogenesis of MRONJ/ARONJ. Medications that can lead to MRONJ/ARONJ are commonly used to treat osteoporosis and to prevent bone fractures caused by bone metastasis of malignancies. The long-standing disease state of ONJ deteriorates the quality of life of affected patients. Early detection and prevention of the disease are ke...
Source: Japanese Dental Science Review - January 18, 2019 Category: Dentistry Source Type: research
Effectiveness of current adhesive systems when bonding to CAD/CAM indirect resin materials: A review of 32 publications
Publication date: Available online 23 November 2018Source: Japanese Dental Science ReviewAuthor(s): Atsushi Mine, Tomoshige Kabetani, Asuka Kawaguchi-Uemura, Mami Higashi, Yuko Tajiri, Ryosuke Hagino, Dai Imai, Masahiro Yumitate, Shintaro Ban, Mariko Matsumoto, Hirofumi YataniSummaryThe purpose of this review was to assess the available literature regarding bonding between current adhesive systems and computer-aided design/computer-aided manufacturing (CAD/CAM) indirect resin materials, to provide clinicians with a comparative overview of the relevant bonding procedures. An electronic search was performed through PubMed ba...
Source: Japanese Dental Science Review - November 24, 2018 Category: Dentistry Source Type: research
Crosstalk between Fas and S1P1 signaling via NF-kB in osteoclasts controls bone destruction in the TMJ due to rheumatoid arthritis
We describe that Fas/S1P1 signaling via NF-κB activation in osteoclasts is a key factor in TMJ-RA severity and we discuss a strategy for blocking nuclear translocation of the p50 NF-κB subunit as a potential therapy for attenuating osteoclastogenesis. (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - October 27, 2018 Category: Dentistry Source Type: research
Comparison of immediate and conventional loading protocols with respect to marginal bone loss around implants supporting mandibular overdentures: A systematic review and meta-analysis
ConclusionThe MBLCs of immediately-loaded implants for mandibular IODs seems comparable to those of conventional loading. (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - October 25, 2018 Category: Dentistry Source Type: research
Bone grafting materials in dentoalveolar reconstruction: A comprehensive review
Publication date: Available online 28 September 2018Source: Japanese Dental Science ReviewAuthor(s): S. Titsinides, G. Agrogiannis, T. KaratzasSummaryBone deficits of the jaws are often attributed to accidents, surgical removal of benign lesions or malignant neoplasms, congenital abnormalities, periodontal inflammation, tooth abscess or extraction and finally jaw atrophy due to advanced age or general disease.These bone defects require rehabilitation for a variety of reasons, e.g. maintaining the normal anatomic outline, eliminating empty space, aesthetic restoration and placing dental implants. Today, several techniques h...
Source: Japanese Dental Science Review - October 5, 2018 Category: Dentistry Source Type: research
Current and future options for dental pulp therapy
Publication date: Available online 29 September 2018Source: Japanese Dental Science ReviewAuthor(s): Takahiko Morotomi, Ayako Washio, Chiaki KitamuraSummaryDental pulp is a connective tissue and has functions that include initiative, formative, protective, nutritive, and reparative activities. However, it has relatively low compliance, because it is enclosed in hard tissue. Its low compliance against damage, such as dental caries, results in the frequent removal of dental pulp during endodontic therapy. Loss of dental pulp frequently leads to fragility of the tooth, and eventually, a deterioration in the patient’s qualit...
Source: Japanese Dental Science Review - October 5, 2018 Category: Dentistry Source Type: research
Treatment and evaluation of dysphagia rehabilitation especially on suprahyoid muscles as jaw-opening muscles
In this study, we describe a new dysphagia evaluation method and an exercise that focuses on suprahyoid muscles with application of jaw-opening actions. (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - September 9, 2018 Category: Dentistry Source Type: research
Association of feeding behavior with jaw bone metabolism and tongue pressure
Publication date: Available online 3 September 2018Source: Japanese Dental Science ReviewAuthor(s): Yuko Fujita, Kenshi MakiSummaryIn recent decades, the eating habits of children and adolescents have undergone many changes due to the diversification of lifestyles worldwide. Reduced masticatory function in growing animals results in changes in the mandible, including a decrease in bone mass. However, the influence of different eating behaviors on jaw bone metabolism (e.g., the palatal palate) during the growth period is not fully understood. In addition, recent clinical studies reported that masticatory performance is posi...
Source: Japanese Dental Science Review - September 4, 2018 Category: Dentistry Source Type: research
Mastication as a tool to prevent cognitive dysfunctions
Publication date: Available online 31 August 2018Source: Japanese Dental Science ReviewAuthor(s): Gayathri Krishnamoorthy, Aparna I. Narayana, Dhanasekar BalkrishananSummaryMastication as we all know has always been related to its primary function of digestion, but little do we know that it produces an enhancing effect on general health, especially the cognitive performance related aspects of memory. Recent studies have shown its association with activation of various brain regions, however little is known about its effects on neuronal activity in these specified regions. According to the enormous evidences collected so fa...
Source: Japanese Dental Science Review - September 1, 2018 Category: Dentistry Source Type: research
Evidence-based strategy for dental biofilms: Current evidence of mouthwashes on dental biofilm and gingivitis
Publication date: Available online 31 August 2018Source: Japanese Dental Science ReviewAuthor(s): Shoji Takenaka, Tatsuya Ohsumi, Yuichiro NoiriSummaryTherapeutic mouthwash (MW) is an adjunctive tool along with a regular oral hygiene routine of daily tooth brushing and daily flossing. Previous systematic reviews have demonstrated that it is effective against dental biofilm and gingival inflammation, for prevention of dental caries, and for managing one’s bad breath condition according to the active ingredients. MWs prevent the microorganisms from bacterial adhesion that corresponds to the initial step in biofilm formatio...
Source: Japanese Dental Science Review - September 1, 2018 Category: Dentistry Source Type: research
Effects of blue-light irradiation during dental treatment
Publication date: Available online 31 August 2018Source: Japanese Dental Science ReviewAuthor(s): Fumihiko Yoshino, Ayaka YoshidaSummaryIn dentistry, blue light is widely used for tooth bleaching and restoration procedures involving composite resin. In addition, many dentists use magnification loupes to enable them to provide more accurate dental treatment. Therefore, the use of light is indispensable in dental treatment. However, light can cause various toxicities, and thermal injuries caused by light irradiation are regarded as particularly important. In recent years, the eye damage and non-thermal injuries caused by blu...
Source: Japanese Dental Science Review - September 1, 2018 Category: Dentistry Source Type: research
Structural features, processing mechanism and gene splice variants of dentin sialophosphoprotein
Publication date: Available online 25 August 2018Source: Japanese Dental Science ReviewAuthor(s): Yasuo Yamakoshi, James P. SimmerSummaryDentin sialophosphoprotein (DSPP) plays an important role in the formation of dentin. Understanding its structure and function would provide important insights into the regulation of dentin mineralization. For the past 15 years, we have been studying DSPP-derived proteins isolated from pig dentin. Porcine DSPP is synthesized and secreted by odontoblasts and processed into three proteins, i.e., dentin sialoprotein (DSP), dentin glycoprotein (DGP), and dentin phosphoprotein (DPP), by bone m...
Source: Japanese Dental Science Review - August 26, 2018 Category: Dentistry Source Type: research
Introduction to Kampo medicine for dental treatment — Oral pharmacotherapy that utilizes the advantages of Western and Kampo medicines
Publication date: Available online 25 August 2018Source: Japanese Dental Science ReviewAuthor(s): Pao-Li Wang, Akihiro KanekoSummaryKampo medicine is a medical system that has been systematically organized based on the reactions of the human body. At present, in Western, herbal medicines means the whole herbal product. It is being called Kampo medicine as a medicinal drug in Japan. Since 2012, the “National Health Insurance Drug Price Standards Related to Dental Treatment” published by the Japan Dental Association have included seven Kampo formulations. In 2015, the Japan Dental Association sent a “Kampo Education Pl...
Source: Japanese Dental Science Review - August 26, 2018 Category: Dentistry Source Type: research
Role of Streptococcus mutans surface proteins for biofilm formation
Publication date: February 2018Source: Japanese Dental Science Review, Volume 54, Issue 1Author(s): Michiyo Matsumoto-NakanoSummaryStreptococcus mutans has been implicated as a primary causative agent of dental caries in humans. An important virulence property of the bacterium is its ability to form biofilm known as dental plaque on tooth surfaces. In addition, this organism also produces glucosyltransferases, multiple glucan-binding proteins, protein antigen c, and collagen-binding protein, surface proteins that coordinate to produce dental plaque, thus inducing dental caries. Bacteria utilize quorum-sensing systems to mo...
Source: Japanese Dental Science Review - July 10, 2018 Category: Dentistry Source Type: research
Two novel mechanisms for maintenance of stemness in mesenchymal stem cells: SCRG1/BST1 axis and cell–cell adhesion through N-cadherin
Publication date: February 2018Source: Japanese Dental Science Review, Volume 54, Issue 1Author(s): Naoyuki Chosa, Akira IshisakiSummaryMesenchymal stem cells (MSCs) retain the ability to self-renew and differentiate into mesenchymal cells. Therefore, human MSCs are suitable candidates for use in regenerative medicine and cell therapies. Upon activation by tissue damage, MSCs contribute to tissue repair through a multitude of processes such as self-renewal, migration, and differentiation. However, loss of self-renewal and multi-lineage differentiation potential occurs at a high rate during cell doubling. Effective MSC ther...
Source: Japanese Dental Science Review - July 10, 2018 Category: Dentistry Source Type: research
