Tongue and upper airway function in subjects with and without obstructive sleep apnea
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Takashi Ono Obstructive sleep apnea (OSA) is characterized by repeated occlusion of the oropharyngeal airway during sleep and can have a significant impact on quality of life. In this article, I review the current knowledge of the physiological and pathological functions of the tongue and the genioglossus muscle, one of the upper airway dilatory muscles, in subjects with OSA when they are awake and asleep. Research findings clearly reveal that the genioglossus muscle has important functions in maintenance of upper airway...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
The neuro-osteogenic network: The sympathetic regulation of bone resorption
Publication date: August 2012 Source:Japanese Dental Science Review, Volume 48, Issue 2 Author(s): Akifumi Togari , Michitsugu Arai , Hisataka Kondo , Daisuke Kodama , Yuka Niwa Bone is innervated by sympathetic and sensory neurons, which play important roles in bone remodeling. Direct neuro-osteogenic cross-talk has been demonstrated using an in vitro co-culture model comprising osteoblastic or osteoclastic cells, and neurite-spouting mouse superior cervical ganglia, suggesting that these cells are directly regulated by sympathetic neurons. The increase in sympathetic nervous activity causes bone loss through inc...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Tobacco interventions by dentists and dental hygienists
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Takashi Hanioka , Miki Ojima , Yoko Kawaguchi , Yukio Hirata , Hiroshi Ogawa , Yumiko Mochizuki Tobacco use is a modifiable risk factor for oral disease. Dental professionals are able to reduce the burden of oral and overall health by influencing tobacco use. Results of electronic searches for literature indicated progress in tobacco interventions in dentistry. Patients believed that dentists should routinely offer smoking cessation services, and those interested in quitting felt comfortable receiving advice about...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Research on the mesenchymal stem cells in the maxillo-facial region and bone tissue regeneration
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Makoto Tsuchimochi (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Bone regeneration from mesenchymal stem cells (MSCs) and compact bone-derived MSCs as an animal model
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Eiki Yamachika , Seiji Iida Mesenchymal stem cells (MSCs) have emerged as a promising alternative to traditional surgical techniques. The purpose of this review is to document the current state of research and identify future research directions. At present, no specific markers have been shown to specifically identify MSCs. The most commonly reported positive markers are CD105, CD90, CD44, CD73, CD29, CD13, CD34, CD146, CD106, CD54 and CD166. The most frequently reported negative markers are CD34, CD14, CD45, CD11b, C...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
New tachykinin peptides and nociception
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Toshikazu Nishimori , Rumi Naono-Nakayama , Tetsuya Ikeda Hemokinin-1 (HK-1) and endokinins are peptides predicted from a new mammalian tachykinin gene, TAC4. The amino acid sequences derived from rat/mouse HK-1 and human HK-1 are not identical; however, the effects induced by intracerebroventricular or intrathecal administration of HK-1 are attenuated by treatment with antagonists of neurokinin 1 (NK1) receptor, substance P (SP) receptor, indicating that HK-1 is an agonist of the NK1 receptor. On the other hand, a g...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Review scaffold design and stem cells for tooth regeneration
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Li Zhang , Yosry Morsi , Yanying Wang , Yubao Li , Seeram Ramakrishna Current dental treatments for the missing teeth depend largely on dentures and implants crowned with prosthetic caps to restore some functionality of the teeth. However, these devices cannot mimic the biological teeth, do not remodel and they have poor integration with the host. The concept of tissue engineering is based on that fact that by cultivating postnatal dental stem cells (DSCs) on a well-designed bioengineered three dimensional scaffold...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
The dawn of modern dentistry in Japan: The transfer of knowledge and skills from foreign dentists to Japanese counterparts in the Yokohama Foreign Settlement
Publication date: February 2013 Source:Japanese Dental Science Review, Volume 49, Issue 1 Author(s): Toshihide Ohno , Yuji Hasaka Modern Western dentistry was introduced to Japan by foreign dentists who arrived in Yokohama, after the opening of the country. The arrival in Japan of foreign dentists triggered the introduction of modern dentistry into Japan. We searched through advertisements in the English and Japanese language newspapers published in the Yokohama Settlement to trace the footsteps of these foreign dentists. This paper traces the early history of modern dentistry in Japan from 1865 to 1912 by dividing t...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Cell cycle control factors and skeletal development
Publication date: May 2013 Source:Japanese Dental Science Review, Volume 49, Issue 2 Author(s): Toru Ogasawara In the oral and maxillofacial region, conditions such as delayed bone healing after tooth extraction, bone fracture, trauma-induced bone or cartilage defects, and tumors or birth defects are common, and it is necessary to identify the molecular mechanisms that control skeletogenesis or the differentiation of cells, in order to establish new treatment strategies for these conditions. Multiple studies have been conducted to investigate the involvement of factors that may be crucial for skeletogenesis or the dif...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Medical microbiological approach to Archaea in oral infectious diseases
Publication date: May 2013 Source:Japanese Dental Science Review, Volume 49, Issue 2 Author(s): Hiroshi Maeda , Kimito Hirai , Junji Mineshiba , Tadashi Yamamoto , Susumu Kokeguchi , Shogo Takashiba Recent advances in molecular biological techniques have yielded large amounts of information regarding the oral microflora. The microbiological communities were shown to be more diverse than previously thought and to include a number of previously uncharacterized microorganisms. The range of research targets of microorganisms associated with oral diseases has been expanded to include these unknown or uncharacterized o...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Octacalcium phosphate (OCP)-based bone substitute materials
Publication date: May 2013 Source:Japanese Dental Science Review, Volume 49, Issue 2 Author(s): Osamu Suzuki The present article summarizes the characteristics of a synthetic octacalcium phosphate (OCP) and OCP-based materials. We previously established a method for a relatively large scale synthesis of OCP and showed that OCP enhances bone regeneration more than hydroxyapatite (HA) materials, including HA obtained through hydrolysis of OCP, coupled with material biodegradation if implanted in various bone defects. One of the OCP-based materials consisting of OCP and natural polymers, such as gelatin, induced a bone r...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
The dawn of modern dentistry in Japan
Publication date: May 2013 Source:Japanese Dental Science Review, Volume 49, Issue 2 Author(s): Masashi Sugisaki (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Detection of field alterations using useful tools for oral squamous cell carcinoma
Publication date: August 2013 Source:Japanese Dental Science Review, Volume 49, Issue 3 Author(s): Takeshi Nomura , Takahiko Shibahara It is known that a region of epithelial dysplasia cannot easily be distinguished macroscopically from normal looking area surrounding early oral squamous cell carcinoma (OSCC). In 1953, Slaughter emphasized field cancerization and the importance of examining the fields surrounding OSCC. Since 1997, we have used vital staining with iodine for detecting surgical margin and investigated the usefulness of this method. From a pathological point of view, various types of dysplasia in iodine...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Income and expenditure in private dental clinics in Japan
Publication date: August 2013 Source:Japanese Dental Science Review, Volume 49, Issue 3 Author(s): Midori Tsuneishi , Tatsuo Yamamoto , Takuo Ishii Although national dental care expenditure has not changed, the number of dental clinics has increased. Mass media has been reporting on the financial difficulties of dental clinics. To address this issue, we reviewed articles that showed the distribution and changes in net income, that is, total expenses subtracted from total income, of private dental clinics in Japan using data from a survey conducted by the Japan Dental Association. We also reviewed articles analyzing ...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Guideline of primary treatment of temporomandibular disorders using GRADE approach
Publication date: August 2013 Source:Japanese Dental Science Review, Volume 49, Issue 3 Author(s): Masashi Sugisaki (Source: Japanese Dental Science Review)
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
