Applications of X-ray fluorescence analysis (XRF) to dental and medical specimens
Publication date: Available online 29 August 2014 Source:Japanese Dental Science Review Author(s): Motohiro Uo , Takahiro Wada , Tomoko Sugiyama Human tissues contain many kinds of minerals and trace essential elements that act as catalytic or structural components of large biochemical molecules. In addition, various metallic and inorganic materials are used in dental and medical materials and devices. In the dental and medical fields, specimens that are wet and/or have low heat resistance are often requested for elemental analysis. Therefore, a rapid and non-destructive method of elemental analysis is required. X-r...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Bone morphogenetic protein-induced heterotopic bone formation: What have we learned from the history of a half century?
Publication date: Available online 27 September 2014 Source:Japanese Dental Science Review Author(s): Takenobu Katagiri , Kenji Osawa , Sho Tsukamoto , Mai Fujimoto , Arei Miyamoto , Takato Mizuta Bone morphogenetic protein (BMP) was originally discovered by Marshall Urist a half century ago following the observation of a unique activity that induced heterotopic bone formation in skeletal muscle tissue. The molecular mechanisms underlying the induction of heterotopic bone formation in skeletal muscle by BMPs were elucidated through the purification and molecular cloning of BMPs and identification of their functio...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Molecular aspects in inflammatory events of temporomandibular joint: Microarray-based identification of mediators
Publication date: Available online 11 October 2014 Source:Japanese Dental Science Review Author(s): Naomi Ogura , Toshirou Kondoh Synovial inflammation (synovitis) frequently accompanies intracapsular pathologic conditions of the temporomandibular joint (TMJ) such as internal derangement (ID) and/or osteoarthritis (OA), and is suggested to be associated with symptom severity. To identify the putative factors associated with synovitis, we investigated interleukin (IL)-1β- and/or tumor necrosis factor (TNF)-α-responsive genes of fibroblast-like synoviocytes (FLS) from patients with ID and/or OA of TMJ using microarra...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Molecular biological change in oral cancer, summary of our researches
Publication date: Available online 13 October 2014 Source:Japanese Dental Science Review Author(s): Nobuharu Yamamoto , Takeshi Onda , Keisuke Sugahara , Takeshi Nomura , Takahiko Shibahara Molecular biological search and identification of cancer have a variety of clinical significance. Microarray, proteomics and metabolome analyses are powerful analytical methods for rapid screening of tumor markers. From the results, it was revealed that a number of genes are specifically expressed in oral cancers. From the results of CAN and LOH analyses of the entire genome, three candidate gene loci (D1S1189, D1S2151, D1S2595...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Morphological variation of the maxillary lateral incisor
Publication date: November 2014 Source:Japanese Dental Science Review, Volume 50, Issue 4 Author(s): Shintaro Kondo , Grant Townsend , Masanobu Matsuno The maxillary lateral incisor is a variable tooth morphologically. This tooth frequently shows reduction in size, and also various alterations in shape, for example, peg-shaped, cone-shaped, barrel-shaped and canine-shaped. The lateral incisor variant can be analyzed by family studies and using twin models, and these approaches have shown that genetic, epigenetic and environmental factors can all contribute to variation in the trait. Discordance of the phenotype in m...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Cancer/testis antigens: A prospective reagent as diagnostic and immunotherapeutic targets for squamous cell carcinoma of the head and neck
Publication date: November 2014 Source:Japanese Dental Science Review, Volume 50, Issue 4 Author(s): Shohei Domae , Toshiro Ono , Akira Sasaki Numerous tumor antigens have so far been identified from various tumors using the serological identification of antigens by recombinant expression cloning (SEREX) method. Among them, cancer/testis (CT) antigens are considered promising target molecules for immunotherapy for patients with various cancers. We performed several SEREX analyses of various cancers to identify CT antigens, including gastric adenocarcinoma, lung adenocarcinoma, and colon cancer, and consequently iden...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Multidetector computed tomography of maxillofacial fractures
Publication date: November 2014 Source:Japanese Dental Science Review, Volume 50, Issue 4 Author(s): Ichiro Ogura , Yusuke Sasaki , Takashi Kaneda Fracture morphology of maxillofacial trauma is often complex, so the clinicians should be familiar with the imaging findings. Various radiographic methods have been used for diagnosing maxillofacial trauma. In recent years, multidetector computed tomography (MDCT) with multiplanar reformation (MPR) and three-dimensional (3D) images has become a standard part of the assessment of maxillofacial injury because of the exquisite sensitivity of this imaging technique for fractu...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
Risks and complications of miniscrew anchorage in clinical orthodontics
Publication date: November 2014 Source:Japanese Dental Science Review, Volume 50, Issue 4 Author(s): Shingo Kuroda , Eiji Tanaka Miniscrew anchorage has greatly expanded the limit of clinical orthodontics. Even without patient compliance, miniscrews can provide stationary anchorages for various tooth movements and even make it possible to move the tooth in directions which have been impossible with traditional orthodontic mechanics. On the other hand, the clinical use of miniscrew anchorage includes some risks. Screw fracture might be one of the most undesirable side effects in clinical use of miniscrew anchorage, wh...
Source: Japanese Dental Science Review - November 3, 2014 Category: Dentistry Source Type: research
