High-Dose Asian Ginseng (Panax Ginseng) for Cancer-Related Fatigue: A Preliminary Report
Conclusion. PG is safe and improves CRF fatigue as well as overall quality of life, appetite, and sleep at night. Randomized controlled trials of PG for CRF are justified. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 14, 2015 Category: Cancer & Oncology Authors: Yennurajalingam, S., Reddy, A., Tannir, N. M., Chisholm, G. B., Lee, R. T., Lopez, G., Escalante, C. P., Manzullo, E. F., Frisbee Hume, S., Williams, J. L., Cohen, L., Bruera, E. Tags: Articles Source Type: research

Effects of a 15-Month Supervised Exercise Program on Physical and Psychological Outcomes in Prostate Cancer Patients Following Prostatectomy: The ProRehab Study
Conclusions. The presented data hint at the potential of rehabilitative sports groups for prostate cancer patients. However, according to the current state of the art, exercise intensity and volume may need to be increased to enhance the effects. A number of shorter studies (8-24 weeks) have proven significant between-group differences in quality of life, incontinence, and fitness outcomes when patients exercised 2 to 3 times per week. This is the first exercise intervention study with prostate cancer patients that was conducted over 15 months. Further studies are necessary to investigate whether prostate cancer patients r...
Source: Integrative Cancer Therapies - August 14, 2015 Category: Cancer & Oncology Authors: Zopf, E. M., Bloch, W., Machtens, S., Zumbe, J., Rubben, H., Marschner, S., Kleinhorst, C., Schulte-Frei, B., Herich, L., Felsch, M., Predel, H.-G., Braun, M., Baumann, F. T. Tags: Articles Source Type: research

In This Issue
(Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - August 14, 2015 Category: Cancer & Oncology Authors: Block, K. I. Tags: Editorial Source Type: research

Inhibition of Hepatocellular Carcinoma by Total Alkaloids of Rubus alceifolius Poir Involves Suppression of Hedgehog Signaling
Conclusion. Our study showed that TARAP inhibits HCC migration and invasion likely through suppression of the hedgehog pathway. This may, in part, explain its anticancer properties. These results suggest that total alkaloids in Rubus alceifolius may have potential as a novel antimetastasis drug in the treatment of HCC. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Zhao, J., Liu, L., Wan, Y., Zhang, Y., Zhuang, Q., Zhong, X., Hong, Z., Peng, J. Tags: Articles Source Type: research

Transient Receptor Potential Channel and Interleukin-17A Involvement in LTTL Gel Inhibition of Bone Cancer Pain in a Rat Model
Cancer pain management is a challenge for which Chinese herbal medicine might be useful. To study the spinal mechanisms of the Chinese medicated gel Long-Teng-Tong-Luo (LTTL), a 7-herb compound, on bone cancer pain, a bone cancer pain model was made by inoculating the tibias of female rats with Walker 256 cells. LTTL gel or inert gel, 0.5 g/cm2/d, was applied to the skin of tumor-bearing tibias for 21 days beginning a day after the inoculation. Mechanical threshold and paw withdrawal latency to thermal stimulation was measured. Transient receptor potential (TRP) cation channels in lumbar dorsal root ganglia (DRG) were immu...
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Wang, J., Zhang, R., Dong, C., Jiao, L., Xu, L., Liu, J., Wang, Z., Lao, L. Tags: Articles Source Type: research

An Exploratory Study of the Effects of Mind-Body Interventions Targeting Sleep on Salivary Oxytocin Levels in Cancer Survivors
Cancer survivors experience high levels of distress, associated with a host of negative psychological states, including anxiety, depression, and fear of recurrence, which often lead to sleep problems and reduction in quality of life (QOL) and well-being. As a neuropeptide hormone associated with affiliation, calmness, and well-being, oxytocin may be a useful biological measure of changes in health outcomes in cancer survivors. In this exploratory study, which comprised a subset of participants from a larger study, we evaluated (a) the feasibility and reliability of salivary oxytocin (sOT) levels in cancer survivors and (b)...
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Lipschitz, D. L., Kuhn, R., Kinney, A. Y., Grewen, K., Donaldson, G. W., Nakamura, Y. Tags: Articles Source Type: research

Use of Traditional Indigenous Medicine and Complementary Medicine Among Indigenous Cancer Patients in Queensland, Australia
Conclusion. A substantial percentage of Indigenous Australians reported using TM/CAM for their cancer care, and there is a need to expand examination of this area of health care using large-scale studies focusing on in-depth specific cancer(s). (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Adams, J., Valery, P. C., Sibbritt, D., Bernardes, C. M., Broom, A., Garvey, G. Tags: Articles Source Type: research

Complementary and Alternative Medicine Use in Cancer Patients in Rural Australia
Conclusion. This study supports previous research that CAM use is as common in regional and remote areas as metropolitan areas. Nondisclosure of CAM use to health professionals was common. Future research needs to focus on strategies to improve communication between patients and health professionals about the use of CAM. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Sullivan, A., Gilbar, P., Curtain, C. Tags: Articles Source Type: research

The Impact of a Multidimensional Exercise Intervention on Physical and Functional Capacity, Anxiety, and Depression in Patients With Advanced-Stage Lung Cancer Undergoing Chemotherapy
Conclusion. The results of the present study show that during a 6-week hospital-based supervised, structured, and group-based exercise program, patients with advanced-stage lung cancer (NSCLC IIIb-IV, ED-SCLC) improve their physical capacity (VO2peak, 1RM), functional capacity, anxiety level, and emotional well-being, but not their overall HRQoL. A randomized controlled trial testing the intervention including 216 patients is currently being carried out. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Quist, M., Adamsen, L., Rorth, M., Laursen, J. H., Christensen, K. B., Langer, S. W. Tags: Articles Source Type: research

A Systematic Review of the Safety and Effect of Neurofeedback on Fatigue and Cognition
Conclusions. Despite issues with methodological quality, the overall positive findings and few reported side effects suggest neurofeedback could be helpful in alleviating fatigue and cognitive impairment. Currently, there is insufficient evidence that neurofeedback is an effective therapy for management of these symptoms in cancer survivors, however, these promising results support the need for further research with this patient population. More information about which neurofeedback technologies, approaches, and protocols could be successfully used with cancer survivors and with minimal side effects is needed. This researc...
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Luctkar-Flude, M., Groll, D. Tags: Articles Source Type: research

Survey of Policies and Guidelines on Antioxidant Use for Cancer Prevention, Treatment, and Survivorship in North American Cancer Centers: What Do Institutions Perceive as Evidence?
Conclusions. Policies and guidelines on antioxidants from diet were largely consistent with the research evidence. Policies and guidelines on antioxidant supplements during treatment were generally more restrictive than the research evidence might suggest, perhaps due to the specificity of results and the inability to generalize findings across antioxidants, adding to the complexity of their optimal and safe use. Improved communication of comprehensive research evidence to cancer institutions may aid in the development of more evidence-based policies and guidelines. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Hong, G., White, J., Zhong, L., Carlson, L. E. Tags: Articles Source Type: research

Meta-Analysis of Massage Therapy on Cancer Pain
Cancer pain is the most common complaint among patients with cancer. Conventional treatment does not always relieve cancer pain satisfactorily. Therefore, many patients with cancer have turned to complementary therapies to help them with their physical, emotional, and spiritual well-being. Massage therapy is increasingly used for symptom relief in patients with cancer. The current study aimed to investigate by meta-analysis the effects of massage therapy for cancer patients experiencing pain. Nine electronic databases were systematically searched for studies published through August 2013 in English, Chinese, and Korean. Me...
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Lee, S.-H., Kim, J.-Y., Yeo, S., Kim, S.-H., Lim, S. Tags: Articles Source Type: research

In This Issue
(Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Block, K. I. Tags: Editorial Source Type: research

Analgesic Effect of Chinese Herbal Formula Hua-Jian-Ba-Du Ointment on Visceral Pain in Mice Induced by Acetic Acid
Conclusion. Our results exhibited the analgesic effect of HJBDO on visceral pain in mice, and this effect might be mediated by the regulation of inflammation and neurotransmitters. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - April 13, 2015 Category: Cancer & Oncology Authors: Ma, S., Zhang, Y., Li, X., Zhang, H., Jia, Y. Tags: Articles Source Type: research

Antimetastatic Effects of Celastrus orbiculatus on Human Gastric Adenocarcinoma by Inhibiting Epithelial-Mesenchymal Transition and NF-{kappa}B/Snail Signaling Pathway
Conclusion. Our findings provided new evidence that COE is an effective inhibitor of metastatic potential of SGC-7901 cells through suppression of EMT and NF-B/Snail signal pathway. Based on these findings, COE may be considered a novel anticancer agent for the treatment of metastasis in gastric cancer. (Source: Integrative Cancer Therapies)
Source: Integrative Cancer Therapies - April 13, 2015 Category: Cancer & Oncology Authors: Zhu, Y., Liu, Y., Qian, Y., Dai, X., Yang, L., Chen, J., Guo, S., Hisamitsu, T. Tags: Articles Source Type: research