Inhibition of Hepatocellular Carcinoma by Total Alkaloids of Rubus alceifolius Poir Involves Suppression of Hedgehog Signaling

Conclusion. Our study showed that TARAP inhibits HCC migration and invasion likely through suppression of the hedgehog pathway. This may, in part, explain its anticancer properties. These results suggest that total alkaloids in Rubus alceifolius may have potential as a novel antimetastasis drug in the treatment of HCC.

Source: Integrative Cancer Therapies - June 21, 2015 Category: Cancer & Oncology Authors: Zhao, J., Liu, L., Wan, Y., Zhang, Y., Zhuang, Q., Zhong, X., Hong, Z., Peng, J. Tags: Articles Source Type: research